STRINGSTRING
bdhT bdhT dut dut groS groS A4SRZ5_AERS4 A4SRZ5_AERS4 cpdB cpdB A4SS77_AERS4 A4SS77_AERS4 pyrE pyrE A4SHE3_AERS4 A4SHE3_AERS4 upp upp nrdB nrdB nrdA nrdA pyrD pyrD rlmL rlmL A4SR73_AERS4 A4SR73_AERS4 A4SR72_AERS4 A4SR72_AERS4 A4SQV1_AERS4 A4SQV1_AERS4 A4SQR5_AERS4 A4SQR5_AERS4 A4SQK2_AERS4 A4SQK2_AERS4 pyrH pyrH A4ST56_AERS4 A4ST56_AERS4 dho dho A4SHV2_AERS4 A4SHV2_AERS4 tdk tdk setA setA cmk cmk pyrF pyrF A4SK59_AERS4 A4SK59_AERS4 GCA_000820065_02786 GCA_000820065_02786 GCA_000820065_02785 GCA_000820065_02785 A4SM39_AERS4 A4SM39_AERS4 GCA_000820065_02718 GCA_000820065_02718 A4SJZ3_AERS4 A4SJZ3_AERS4 deoA deoA deoD-2 deoD-2 A4SRP5_AERS4 A4SRP5_AERS4 A4SN29_AERS4 A4SN29_AERS4 psuG psuG A4SJD5_AERS4 A4SJD5_AERS4 pyrC pyrC udp2 udp2 A4SIR1_AERS4 A4SIR1_AERS4 thyA thyA A4SNE6_AERS4 A4SNE6_AERS4 cdd cdd pyrB pyrB pyrI pyrI nrdR nrdR deoD deoD surE surE pyrG pyrG mazG mazG nrdD nrdD A4SK90_AERS4 A4SK90_AERS4 A4SK83_AERS4 A4SK83_AERS4 udp udp rlmI rlmI udk udk dcd dcd tmk tmk nucH nucH ppnP ppnP carB carB carA carA A4SNZ7_AERS4 A4SNZ7_AERS4 ndk ndk tgt tgt
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bdhTUnannotated protein. (379 aa)
dutUnannotated protein; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa)
groSUnannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (97 aa)
A4SRZ5_AERS4Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
cpdBUnannotated protein; Belongs to the 5'-nucleotidase family. (659 aa)
A4SS77_AERS4Unannotated protein. (222 aa)
pyrEUnannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (217 aa)
A4SHE3_AERS4Unannotated protein. (165 aa)
uppUnannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa)
nrdBUnannotated protein. (377 aa)
nrdAUnannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (755 aa)
pyrDUnannotated protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa)
rlmLUnannotated protein; Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. Belongs to the methyltransferase superfamily. RlmKL family. (731 aa)
A4SR73_AERS4Unannotated protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (715 aa)
A4SR72_AERS4Unannotated protein. (227 aa)
A4SQV1_AERS4Unannotated protein; Belongs to the 5'-nucleotidase family. (612 aa)
A4SQR5_AERS4Unannotated protein. (277 aa)
A4SQK2_AERS4Unannotated protein. (472 aa)
pyrHUnannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (244 aa)
A4ST56_AERS4Unannotated protein. (362 aa)
dhoUnannotated protein. (379 aa)
A4SHV2_AERS4Unannotated protein. (126 aa)
tdkUnannotated protein. (193 aa)
setAUnannotated protein. (390 aa)
cmkUnannotated protein. (230 aa)
pyrFUnannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (233 aa)
A4SK59_AERS4Unannotated protein; Belongs to the 5'-nucleotidase family. (662 aa)
GCA_000820065_02786Unannotated protein. (127 aa)
GCA_000820065_02785Unannotated protein. (303 aa)
A4SM39_AERS4Unannotated protein; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (196 aa)
GCA_000820065_02718Unannotated protein. (228 aa)
A4SJZ3_AERS4Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (289 aa)
deoAUnannotated protein; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (443 aa)
deoD-2Unannotated protein. (238 aa)
A4SRP5_AERS4Unannotated protein. (302 aa)
A4SN29_AERS4Unannotated protein. (226 aa)
psuGUnannotated protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (302 aa)
A4SJD5_AERS4Unannotated protein. (714 aa)
pyrCUnannotated protein. (447 aa)
udp2Unannotated protein. (241 aa)
A4SIR1_AERS4Unannotated protein. (508 aa)
thyAUnannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
A4SNE6_AERS4Unannotated protein; Belongs to the 5'-nucleotidase family. (553 aa)
cddUnannotated protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (293 aa)
pyrBUnannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (306 aa)
pyrIUnannotated protein; Involved in allosteric regulation of aspartate carbamoyltransferase. (154 aa)
nrdRUnannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (149 aa)
deoDUnannotated protein. (233 aa)
surEUnannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (248 aa)
pyrGUnannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa)
mazGUnannotated protein. (265 aa)
nrdDUnannotated protein. (705 aa)
A4SK90_AERS4Unannotated protein. (421 aa)
A4SK83_AERS4Unannotated protein; Belongs to the UPF0301 (AlgH) family. (184 aa)
udpUnannotated protein; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (251 aa)
rlmIUnannotated protein; Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA. (396 aa)
udkUnannotated protein. (214 aa)
dcdUnannotated protein; Catalyzes the deamination of dCTP to dUTP. (193 aa)
tmkUnannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa)
nucHUnannotated protein. (1072 aa)
ppnPUnannotated protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa)
carBUnannotated protein; Belongs to the CarB family. (1074 aa)
carAUnannotated protein; Belongs to the CarA family. (383 aa)
A4SNZ7_AERS4Unannotated protein. (77 aa)
ndkUnannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (142 aa)
tgtUnannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. A [...] (378 aa)
Your Current Organism:
Aeromonas salmonicida
NCBI taxonomy Id: 29491
Other names: A. salmonicida subsp. salmonicida, Aeromonas salmonicida salmonicida, Aeromonas salmonicida subsp. salmonicida
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.