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| | BF0179 | Conserved hypothetical protein; Similar to gp:AE016940_18 [Bacteroides thetaiotaomicron VPI-5482], percent identity 83 in 206 aa, BLASTP E(): e-105. (214 aa) |
| | BF0214 | Snf2 family helicase; Similar to gp:AE016940_54 [Bacteroides thetaiotaomicron VPI-5482], percent identity 61 in 1033 aa, BLASTP E(): 0.0. (1016 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (290 aa) |
| | acpP | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (78 aa) |
| | rimP | Conserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (155 aa) |
| | nusA | Putative nitrogen utilization substance protein; Participates in both transcription termination and antitermination. (420 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (1015 aa) |
| | rpsT | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. (84 aa) |
| | BF0374 | Peptide chain release factor RF-2; Similar to gp:AE016941_39 [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 319 aa, BLASTP E(): e-171. (319 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). (188 aa) |
| | rpmH | 50S ribosomal protein L34; Similar to gp:AE016941_196 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 52 aa, BLASTP E(): 8e-22; Belongs to the bacterial ribosomal protein bL34 family. (53 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (117 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (186 aa) |
| | rsfS | Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (119 aa) |
| | BF1007 | seryl-tRNA synthetase; Similar to gp:AE016944_168 [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 424 aa, BLASTP E(): 0.0. (424 aa) |
| | rpmA | 50S ribosomal protein L27; Similar to gp:AE016944_169 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 89 aa, BLASTP E(): 4e-44; Belongs to the bacterial ribosomal protein bL27 family. (89 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (105 aa) |
| | BF1031 | Conserved hypothetical protein; Similar to gp:AE016944_188 [Bacteroides thetaiotaomicron VPI-5482], percent identity 81 in 209 aa, BLASTP E(): 2e-95. (216 aa) |
| | BF1043 | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. (597 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (876 aa) |
| | secA | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1109 aa) |
| | BF1084 | Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (126 aa) |
| | nnrD | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] (503 aa) |
| | BF1092 | Putative transcriptional regulator UpxY homolog; Similar to gp:AF048749_3 [Bacteroides fragilis NCTC9343], percent identity 100 in 113 aa, BLASTP E(): 6e-59. (113 aa) |
| | obg | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (386 aa) |
| | rplY | Putative 50S ribosomal protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (196 aa) |
| | BF1200 | Conserved hypothetical protein; Similar to gp:AE016945_236 [Bacteroides thetaiotaomicron VPI-5482], percent identity 90 in 105 aa, BLASTP E(): 1e-45. (108 aa) |
| | BF1432 | Putative acyl carrier protein; Similar to sp:ACP_THETN [Thermoanaerobacter tengcongensis], percent identity 37 in 49 aa, BLASTP E():0.003. (73 aa) |
| | BF1552 | Similar to gp:AE016932_32 [Bacteroides thetaiotaomicron VPI-5482], percent identity 94 in 524 aa, BLASTP E(): 0.0. (524 aa) |
| | BF1660 | ATP-dependent RNA helicase DeaD; Similar to gp:AE012866_13 [Chlorobium tepidum TLS], percent identity 60 in 414 aa, BLASTP E(): e-141; Belongs to the DEAD box helicase family. (427 aa) |
| | BF1683 | Putative endonuclease; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. (138 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (184 aa) |
| | BF1686 | Conserved hypothetical protein; Similar to gp:AE016927_154 [Bacteroides thetaiotaomicron VPI-5482], percent identity 76 in 690 aa, BLASTP E(): 0.0. (682 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (646 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (203 aa) |
| | rpmI | 50S ribosomal protein L35; Similar to gp:AE016927_157 [Bacteroides thetaiotaomicron VPI-5482], percent identity 98 in 65 aa, BLASTP E(): 3e-30; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (116 aa) |
| | atpD | ATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (505 aa) |
| | BF2172 | ATP synthase epsilon chain; Similar to gp:AE016928_225 [Bacteroides thetaiotaomicron VPI-5482], percent identity 79 in 81 aa, BLASTP E(): 1e-29. (81 aa) |
| | BF2173 | Conserved hypothetical protein; Similar to gp:AE016928_226 [Bacteroides thetaiotaomicron VPI-5482], percent identity 62 in 143 aa, BLASTP E(): 8e-48. (142 aa) |
| | atpB | ATP synthase A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (383 aa) |
| | atpE | ATP synthase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (85 aa) |
| | atpF | ATP synthase B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (165 aa) |
| | atpH | ATP synthase delta chain; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (186 aa) |
| | atpA | ATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (527 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (290 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1141 aa) |
| | BF2280 | Putative tRNA/rRNA methyltransferase; Similar to gp:AE016929_81 [Bacteroides thetaiotaomicron VPI-5482], percent identity 77 in 250 aa, BLASTP E(): e-112; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (253 aa) |
| | BF2299 | ATP-dependent RNA helicase; Similar to gp:AE016929_101 [Bacteroides thetaiotaomicron VPI-5482], percent identity 89 in 410 aa, BLASTP E(): 0.0; Belongs to the DEAD box helicase family. (418 aa) |
| | BF2301 | Conserved hypothetical protein; Similar to gp:AE016929_103 [Bacteroides thetaiotaomicron VPI-5482], percent identity 81 in 165 aa, BLASTP E(): 3e-70. (169 aa) |
| | ftsY | Recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (319 aa) |
| | rpmG | 50S ribosomal protein L33; Similar to gp:AE016929_185 [Bacteroides thetaiotaomicron VPI-5482], percent identity 98 in 62 aa, BLASTP E(): 9e-29; Belongs to the bacterial ribosomal protein bL33 family. (62 aa) |
| | rpmB | 50S ribosomal protein L28; Similar to gp:AE016929_186 [Bacteroides thetaiotaomicron VPI-5482], percent identity 95 in 86 aa, BLASTP E(): 3e-43; Belongs to the bacterial ribosomal protein bL28 family. (86 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (497 aa) |
| | BF2539 | RNA methyltransferase; Similar to gp:AE016928_156 [Bacteroides thetaiotaomicron VPI-5482], percent identity 91 in 454 aa, BLASTP E(): 0.0; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (472 aa) |
| | BF2540 | RNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (307 aa) |
| | lepA | GTP-binding protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (593 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Similar to gp:AE016928_139 [Bacteroides thetaiotaomicron VPI-5482], percent identity 91 in 820 aa, BLASTP E(): 0.0; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (820 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (533 aa) |
| | yidC | Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (618 aa) |
| | BF2616 | Conserved hypothetical protein; Similar to gp:AE016928_87 [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 111 aa, BLASTP E(): 3e-55. (111 aa) |
| | BF2702 | Putative acetyltransferase; Similar to gp:AE016931_49 [Bacteroides thetaiotaomicron VPI-5482], percent identity 67 in 146 aa, BLASTP E(): 2e-53. (148 aa) |
| | rpsP | 30S ribosomal protein S16; Similar to sp:RS16_BACTN [Bacteroides thetaiotaomicron VPI-5482], percent identity 91 in 184 aa, BLASTP E(): 2e-86; Belongs to the bacterial ribosomal protein bS16 family. (181 aa) |
| | BF2742 | RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (286 aa) |
| | BF2758 | glutaminyl-tRNA synthetase; Similar to gp:AE016931_116 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 579 aa, BLASTP E(): 0.0. (582 aa) |
| | BF2814 | Hypothetical protein. (245 aa) |
| | BF2943 | Probable helicase; Similar to pir:G85652, percent identity 39 in 799 aa, BLASTP E(): e-162. (970 aa) |
| | rho | Transcription termination factor rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (687 aa) |
| | ffh | Putative signal recognition protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (439 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Similar to gp:AE016932_201 [Bacteroides thetaiotaomicron VPI-5482], percent identity 91 in 339 aa, BLASTP E(): 0.0; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa) |
| | rpmE2 | 50S ribosomal protein L31 type B; Similar to sp:R31B_BACTN [Bacteroides thetaiotaomicron VPI-5482], percent identity 98 in 83 aa, BLASTP E(): 1e-41. (83 aa) |
| | hisS | histidyl-tRNA synthetase; Similar to sp:SYH_BACTN [Bacteroides thetaiotaomicron VPI-5482], percent identity 92 in 452 aa, BLASTP E(): 0.0. (454 aa) |
| | BF3660 | Conserved hypothetical protein; Similar to gpu:BX571875_36 [Photorhabdus luminescens subsp. laumondii TTO1], percent identity 44 in 381 aa, BLASTP E(): 1e-80. (400 aa) |
| | rimM | Probable 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (180 aa) |
| | BF3726 | tRNA and rRNA cytosine-C5-methylase; Similar to gp:AE016934_123 [Bacteroides thetaiotaomicron VPI-5482], percent identity 68 in 492 aa, BLASTP E(): 0.0. (472 aa) |
| | lysS | lysyl-tRNA synthetase; Similar to gp:AE016934_203 [Bacteroides thetaiotaomicron VPI-5482], percent identity 82 in 576 aa, BLASTP E(): 0.0; Belongs to the class-II aminoacyl-tRNA synthetase family. (575 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (147 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (90 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (114 aa) |
| | BF3867 | Elongation factor G; Similar to gp:AE016935_14 [Bacteroides thetaiotaomicron VPI-5482], percent identity 88 in 718 aa, BLASTP E(): 0.0. (718 aa) |
| | BF3960 | Nucleoside diphosphate kinase; Similar to gp:AE016942_198 [Bacteroides thetaiotaomicron VPI-5482], percent identity 92 in 154 aa, BLASTP E(): 1e-78; Belongs to the NDK family. (154 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (330 aa) |
| | rpsB | 30S ribosomal protein S2 (BS1); Similar to gp:AE016942_150 [Bacteroides thetaiotaomicron VPI-5482], percent identity 97 in 278 aa, BLASTP E(): e-150; Belongs to the universal ribosomal protein uS2 family. (278 aa) |
| | rpsI | 30S ribosomal protein S9; Similar to gp:AE016942_149 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 128 aa, BLASTP E(): 2e-64; Belongs to the universal ribosomal protein uS9 family. (128 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (153 aa) |
| | asnS | asparaginyl-tRNA synthetase; Similar to gp:AE016942_146 [Bacteroides thetaiotaomicron VPI-5482], percent identity 94 in 467 aa, BLASTP E(): 0.0. (467 aa) |
| | BF4036 | tryptophanyl-tRNA synthetase; Similar to gp:AE016942_137 [Bacteroides thetaiotaomicron VPI-5482], percent identity 90 in 361 aa, BLASTP E(): 0.0; Belongs to the class-I aminoacyl-tRNA synthetase family. (363 aa) |
| | BF4079 | FKBP-type peptidyl-prolyl cis-transisomerase; Similar to gp:AE016942_114 [Bacteroides thetaiotaomicron VPI-5482], percent identity 81 in 451 aa, BLASTP E(): 0.0. (451 aa) |
| | rpmF | 50S ribosomal protein L32 (Ribosomal protein I); Similar to gp:AE016942_106 [Bacteroides thetaiotaomicron VPI-5482], percent identity 100 in 61 aa, BLASTP E(): 2e-31; Belongs to the bacterial ribosomal protein bL32 family. (61 aa) |
| | BF4091 | Conserved hypothetical protein; Similar to gp:AE016942_105 [Bacteroides thetaiotaomicron VPI-5482], percent identity 84 in 179 aa, BLASTP E(): 4e-86. (178 aa) |
| | rplQ | 50S ribosomal protein L17; Similar to gp:AE016937_40 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 163 aa, BLASTP E(): 5e-81. (161 aa) |
| | rpoA | DNA-directed RNA polymerase alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (330 aa) |
| | rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (201 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (126 aa) |
| | rpmJ | 50S ribosomal protein L36; Similar to gpu:AE017178_168 [Porphyromonas gingivalis W83], percent identity 94 in 38 aa, BLASTP E(): 5e-14; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | map-2 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (265 aa) |
| | secY | Preprotein translocase SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (448 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (148 aa) |
| | rpmD | 50S ribosomal protein L30; Similar to gp:AE016937_49 [Bacteroides thetaiotaomicron VPI-5482], percent identity 98 in 58 aa, BLASTP E(): 9e-24. (58 aa) |
| | rpsE | 30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (172 aa) |
| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (114 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (189 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (131 aa) |
| | rpsN | Chloroplast 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (99 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa) |
| | rplX | 50S ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (106 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (121 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (89 aa) |
| | rpmC | 50S ribosomal protein L29; Similar to sp:RL29_BACTN [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 65 aa, BLASTP E(): 2e-27; Belongs to the universal ribosomal protein uL29 family. (65 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (244 aa) |
| | rplV | 50S ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity). (136 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (89 aa) |
| | rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (274 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (96 aa) |
| | rplD | 50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (208 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (205 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (101 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (705 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (158 aa) |
| | rpsL | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. (133 aa) |
| | rpoC | DNA-directed RNA polymerase beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1427 aa) |
| | rpoB | DNA-directed RNA polymerase beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1270 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (124 aa) |
| | BF4194 | 50S ribosomal protein L10; Similar to gp:AE016937_76 [Bacteroides thetaiotaomicron VPI-5482], percent identity 92 in 170 aa, BLASTP E(): 8e-83. (170 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (232 aa) |
| | rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (147 aa) |
| | nusG | Transcription anti-termination protein; Participates in transcription elongation, termination and antitermination. (180 aa) |
| | secE | Preprotein translocase SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (63 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | BF4200 | Sigma-54 modulation protein; Similar to gp:AE016937_81 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 99 aa, BLASTP E(): 1e-43. (99 aa) |
| | rpsU | 30S ribosomal protein S21; Similar to gpu:AE017173_102 [Porphyromonas gingivalis W83], percent identity 71 in 63 aa, BLASTP E(): 2e-19; Belongs to the bacterial ribosomal protein bS21 family. (63 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (505 aa) |
| | BF4292 | Putative Nudix/MutT family protein; Similar to gp:AE016933_120 [Bacteroides thetaiotaomicron VPI-5482], percent identity 85 in 182 aa, BLASTP E(): 1e-91. (185 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (708 aa) |
| | argS | arginyl-tRNA synthetase; Similar to gp:AE016937_169 [Bacteroides thetaiotaomicron VPI-5482], percent identity 92 in 597 aa, BLASTP E(): 0.0. (597 aa) |
| | secF | Protein-export membrane protein SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (1007 aa) |
| | rpsO | 30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (654 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (714 aa) |
| | leuS | leucyl-tRNA synthetase; Similar to gp:AE016939_36 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 944 aa, BLASTP E(): 0.0; Belongs to the class-I aminoacyl-tRNA synthetase family. (943 aa) |
