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BF0012 BF0012 BF0211 BF0211 BF0229 BF0229 hppA hppA BF0340 BF0340 BF0394 BF0394 BF0407 BF0407 kdpA kdpA kdpB kdpB kdpC kdpC BF0587 BF0587 BF0668 BF0668 nuoN nuoN BF0861 BF0861 BF0862 BF0862 BF0864 BF0864 nuoC nuoC nuoB nuoB nuoA nuoA secA secA BF1084 BF1084 BF1296 BF1296 BF1482 BF1482 BF1559 BF1559 BF1569 BF1569 BF1644 BF1644 BF1739 BF1739 BF1740 BF1740 BF1752 BF1752 BF1924 BF1924 BF2032 BF2032 BF2111 BF2111 BF2112 BF2112 BF2138 BF2138 atpD atpD atpA atpA cobD cobD cobQ cobQ BF2722 BF2722 potA potA BF2729 BF2729 BF2730 BF2730 atpA-2 atpA-2 BF2733 BF2733 BF2734 BF2734 pstB pstB BF2938 BF2938 BF2962 BF2962 BF3029 BF3029 BF3144 BF3144 BF3145 BF3145 BF3184 BF3184 BF3235 BF3235 BF3307 BF3307 BF3785 BF3785 BF3939 BF3939 BF3971 BF3971 BF4039 BF4039 BF4104 BF4104 BF4122 BF4122 BF4297 BF4297 BF4348 BF4348 secF secF BF4556 BF4556
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BF0012ABC transporter ATP-binding protein; Similar to gp:AE016944_144 [Bacteroides thetaiotaomicron VPI-5482], percent identity 62 in 728 aa, BLASTP E(): 0.0. (727 aa)
BF0211Mg2+ transport ATPase protein B; Similar to gp:AE016930_7 [Bacteroides thetaiotaomicron VPI-5482], percent identity 78 in 884 aa, BLASTP E(): 0.0. (883 aa)
BF0229ABC transporter ATP-binding protein; Similar to gp:AE016940_87 [Bacteroides thetaiotaomicron VPI-5482], percent identity 85 in 613 aa, BLASTP E(): 0.0. (611 aa)
hppAPyrophosphate-energized vacuolar membrane proton pump; Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily. (734 aa)
BF0340Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016942_127 [Bacteroides thetaiotaomicron VPI-5482], percent identity 35 in 1034 aa, BLASTP E(): e-168. (1067 aa)
BF0394Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016941_56 [Bacteroides thetaiotaomicron VPI-5482], percent identity 82 in 1022 aa, BLASTP E(): 0.0. (1022 aa)
BF0407Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016935_211 [Bacteroides thetaiotaomicron VPI-5482], percent identity 73 in 1014 aa, BLASTP E(): 0.0. (1019 aa)
kdpAK+-transporting ATPase A chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (568 aa)
kdpBK+-transporting ATPase B chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCK+-transporting ATPase C chain; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (191 aa)
BF0587Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AF329100_8 [Bacteroides fragilis NCTC9343], percent identity 100 in 495 aa, BLASTP E(): 0.0. (495 aa)
BF0668Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016935_211 [Bacteroides thetaiotaomicron VPI-5482], percent identity 46 in 954 aa, BLASTP E(): 0.0. (932 aa)
nuoNNADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (483 aa)
BF0861NADH dehydrogenase I chain M; Similar to gp:AE016943_104 [Bacteroides thetaiotaomicron VPI-5482], percent identity 94 in 494 aa, BLASTP E(): 0.0. (494 aa)
BF0862NADH dehydrogenase I chain L; Similar to gp:AE016943_105 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 643 aa, BLASTP E(): 0.0. (636 aa)
BF0864NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (170 aa)
nuoCNADH dehydrogenase I chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity); In the N-terminal section; belongs to the complex I 30 kDa subunit family. (530 aa)
nuoBNADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (196 aa)
nuoANADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (116 aa)
secAPreprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (1109 aa)
BF1084Putative protein-export membrane protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (126 aa)
BF1296Cation-transporting ATPase; Similar to gp:AE016936_99 [Bacteroides thetaiotaomicron VPI-5482], percent identity 72 in 650 aa, BLASTP E(): 0.0. (648 aa)
BF1482Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016935_43 [Bacteroides thetaiotaomicron VPI-5482], percent identity 29 in 1154 aa, BLASTP E(): e-144. (1131 aa)
BF1559Conserved hypothetical protein; Similar to gp:AE016931_38 [Bacteroides thetaiotaomicron VPI-5482], percent identity 29 in 522 aa, BLASTP E(): 7e-47. (775 aa)
BF1569Outer membrane vitamin B12 receptor protein; Similar to gp:AE016932_21 [Bacteroides thetaiotaomicron VPI-5482], percent identity 75 in 667 aa, BLASTP E(): 0.0. (678 aa)
BF1644Conserved hypothetical protein; Similar to gp:AE016927_61 [Bacteroides thetaiotaomicron VPI-5482], percent identity 72 in 682 aa, BLASTP E(): 0.0. (680 aa)
BF1739Putative outer membrane protein involved in nutrient binding; Similar to gp:AE016927_216 [Bacteroides thetaiotaomicron VPI-5482], percent identity 84 in 917 aa, BLASTP E(): 0.0. (914 aa)
BF1740Putative outer membrane protein involved in nutrient binding; Similar to gp:AE016927_217 [Bacteroides thetaiotaomicron VPI-5482], percent identity 75 in 543 aa, BLASTP E(): 0.0. (543 aa)
BF1752Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016938_194 [Bacteroides thetaiotaomicron VPI-5482], percent identity 32 in 1063 aa, BLASTP E(): e-136. (1048 aa)
BF1924Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016939_149 [Bacteroides thetaiotaomicron VPI-5482], percent identity 41 in 1074 aa, BLASTP E(): 0.0. (1125 aa)
BF2032Cation-transporting ATPase; Similar to gp:AE016930_110 [Bacteroides thetaiotaomicron VPI-5482], percent identity 84 in 736 aa, BLASTP E(): 0.0. (736 aa)
BF2111ABC transporter ATP-binding protein; Similar to gp:AE016928_21 [Bacteroides thetaiotaomicron VPI-5482], percent identity 74 in 599 aa, BLASTP E(): 0.0. (605 aa)
BF2112ABC transporter ATP-binding protein; Similar to gp:AE016928_22 [Bacteroides thetaiotaomicron VPI-5482], percent identity 77 in 576 aa, BLASTP E(): 0.0. (576 aa)
BF2138Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016932_84 [Bacteroides thetaiotaomicron VPI-5482], percent identity 58 in 1115 aa, BLASTP E(): 0.0. (1101 aa)
atpDATP synthase beta chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (505 aa)
atpAATP synthase alpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (527 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa)
cobQCobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (495 aa)
BF2722Putrescine transport system permease protein PotH; Similar to gp:AE016931_81 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 257 aa, BLASTP E(): e-139. (265 aa)
potASpermidine/putrescine transport ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (470 aa)
BF2729V-type ATP synthase subunit I; Similar to gp:AE016931_87 [Bacteroides thetaiotaomicron VPI-5482], percent identity 85 in 600 aa, BLASTP E(): 0.0; Belongs to the V-ATPase 116 kDa subunit family. (605 aa)
BF2730V-type ATP synthase subunit D; Similar to gp:AE016931_88 [Bacteroides thetaiotaomicron VPI-5482], percent identity 94 in 201 aa, BLASTP E(): e-103. (201 aa)
atpA-2V-type ATP synthase subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (585 aa)
BF2733Conserved hypothetical protein; Similar to gp:AE016931_91 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 278 aa, BLASTP E(): e-138. (279 aa)
BF2734ATP synthase subunit E; Similar to gp:AE016931_92 [Bacteroides thetaiotaomicron VPI-5482], percent identity 89 in 196 aa, BLASTP E(): 3e-95. (196 aa)
pstBPutative phosphate transport ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (253 aa)
BF2938Putative oxaloacetate decarboxylase gamma chain 1; Similar to gp:AE016932_230 [Bacteroides thetaiotaomicron VPI-5482], percent identity 80 in 86 aa, BLASTP E(): 5e-31. (85 aa)
BF2962Probable TonB-dependent outer membrane protein; Similar to gpu:AP005345_63 [Vibrio vulnificus YJ016], percent identity 28 in 225 aa, BLASTP E(): 6e-14. (788 aa)
BF3029Putative TonB-dependent outer membrane receptor; Similar to gp:AE016934_34 [Bacteroides thetaiotaomicron VPI-5482], percent identity 100 in 692 aa, BLASTP E(): 0.0. (692 aa)
BF3144ABC transporter ATP-binding protein; Similar to pir:E72396 [Thermotoga maritima], percent identity 41 in 570 aa, BLASTP E(): e-134. (574 aa)
BF3145Multidrug resistance ABC transporter; Similar to pir:F97319, percent identity 46 in 626 aa, BLASTP E(): e-152. (588 aa)
BF3184Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016927_50 [Bacteroides thetaiotaomicron VPI-5482], percent identity 30 in 1136 aa, BLASTP E(): e-109. (1051 aa)
BF3235Probable outer membrane receptor protein; Similar to gpu:AE017179_179 [Porphyromonas gingivalis W83], percent identity 24 in 613 aa, BLASTP E(): 1e-34. (680 aa)
BF3307Outer membrane protein probably involved in nutrient binding; Similar to gp:AE016941_188 [Bacteroides thetaiotaomicron VPI-5482], percent identity 50 in 1016 aa, BLASTP E(): 0.0. (1002 aa)
BF3785Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016943_84 [Bacteroides thetaiotaomicron VPI-5482], percent identity 85 in 1033 aa, BLASTP E(): 0.0. (1071 aa)
BF3939Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016946_109 [Bacteroides thetaiotaomicron VPI-5482], percent identity 27 in 1111 aa, BLASTP E(): e-109. (1098 aa)
BF3971Putative outer membrane protein probably involved in nutrient binding; Similar to gp:AE016935_43 [Bacteroides thetaiotaomicron VPI-5482], percent identity 35 in 1156 aa, BLASTP E(): 0.0. (1146 aa)
BF4039ABC transporter ATP-binding protein; Similar to gp:AE016944_144 [Bacteroides thetaiotaomicron VPI-5482], percent identity 45 in 736 aa, BLASTP E(): 0.0. (736 aa)
BF4104Conserved hypothetical protein; Similar to gp:AE016944_180 [Bacteroides thetaiotaomicron VPI-5482], percent identity 27 in 673 aa, BLASTP E(): 6e-57. (796 aa)
BF4122Conserved hypothetical protein; Similar to pir:H96934, percent identity 25 in 208 aa, BLASTP E(): 2e-11. (257 aa)
BF4297Putative TonB-dependent outer membrane receptor; Similar to gp:AE016929_230 [Bacteroides thetaiotaomicron VPI-5482], percent identity 69 in 613 aa, BLASTP E(): 0.0. (765 aa)
BF4348Putative calcium-transporting ATPase; Similar to gp:AE016936_128 [Bacteroides thetaiotaomicron VPI-5482], percent identity 89 in 894 aa, BLASTP E(): 0.0. (894 aa)
secFProtein-export membrane protein SecD/SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (1007 aa)
BF4556Putative TonB-dependent outer membrane protein; Similar to gp:AE016934_146 [Bacteroides thetaiotaomicron VPI-5482], percent identity 39 in 792 aa, BLASTP E(): e-151. (805 aa)
Your Current Organism:
Bacteroides fragilis
NCBI taxonomy Id: 295405
Other names: B. fragilis YCH46, Bacteroides fragilis YCH46, Bacteroides fragilis str. YCH46, Bacteroides fragilis strain YCH46
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