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BF3372 BF3372 tyrS tyrS cysS cysS mnmA1 mnmA1 BF0445 BF0445 BF0533 BF0533 BF0582 BF0582 guaA guaA panC panC valS valS BF1179 BF1179 mnmA2 mnmA2 tilS tilS queC queC cysD cysD BF1832 BF1832 BF2121 BF2121 ileS ileS BF2578 BF2578 BF2639 BF2639 BF2758 BF2758 nadE nadE BF3373 BF3373 nadD nadD mnmA3 mnmA3 BF4036 BF4036 gltX gltX BF4346 BF4346 argS argS metG metG coaD coaD leuS leuS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BF3372Electron transfer flavoprotein beta-subunit; Similar to gp:AE016933_91 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 290 aa, BLASTP E(): e-155. (290 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (430 aa)
cysScysteinyl-tRNA synthetase; Similar to gp:AE016940_52 [Bacteroides thetaiotaomicron VPI-5482], percent identity 89 in 493 aa, BLASTP E(): 0.0; Belongs to the class-I aminoacyl-tRNA synthetase family. (491 aa)
mnmA1tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (364 aa)
BF0445Na+/H+ antiporter; Similar to gp:AE016941_124 [Bacteroides thetaiotaomicron VPI-5482], percent identity 89 in 711 aa, BLASTP E(): 0.0. (711 aa)
BF0533Argininosuccinate synthase; Similar to gp:AE016942_33 [Bacteroides thetaiotaomicron VPI-5482], percent identity 93 in 400 aa, BLASTP E(): 0.0. (401 aa)
BF0582Osmosensitive K+ channel histidine kinase; Similar to gp:AF329100_3 [Bacteroides fragilis NCTC9343], percent identity 100 in 375 aa, BLASTP E(): 0.0. (375 aa)
guaAGlutaminne-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (507 aa)
panCPantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (876 aa)
BF1179Conserved hypothetical protein; Similar to gp:AE016945_202 [Bacteroides thetaiotaomicron VPI-5482], percent identity 85 in 248 aa, BLASTP E(): e-123; Belongs to the TtcA family. (249 aa)
mnmA2Putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (353 aa)
tilSPutative cell-cycle protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (435 aa)
queCPutative aluminum resistance protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (220 aa)
cysDSulfate adenylyltransferase subunit 2; Similar to gp:AE016927_147 [Bacteroides thetaiotaomicron VPI-5482], percent identity 96 in 301 aa, BLASTP E(): e-170. (303 aa)
BF1832Putative phosphoenolpyruvate phosphomutase; Similar to gp:AF285774_12 [Bacteroides fragilis NCTC9343], percent identity 100 in 433 aa, BLASTP E(): 0.0. (460 aa)
BF2121Conserved hypothetical protein; Similar to gp:AE016930_89 [Bacteroides thetaiotaomicron VPI-5482], percent identity 86 in 433 aa, BLASTP E(): 0.0. (434 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1141 aa)
BF2578Putative phosphoenolpyruvate phosphomutase; Similar to gp:AF285774_12 [Bacteroides fragilis NCTC9343], percent identity 71 in 431 aa, BLASTP E(): 2e-178. (435 aa)
BF2639Similar to gp:AE016928_64 [glutamine-hydrolyzing], percent identity 85 in 558 aa, BLASTP E(): 0.0. (558 aa)
BF2758glutaminyl-tRNA synthetase; Similar to gp:AE016931_116 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 579 aa, BLASTP E(): 0.0. (582 aa)
nadEGlutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (641 aa)
BF3373Electron transfer flavoprotein alpha-subunit; Similar to gp:AE016933_92 [Bacteroides thetaiotaomicron VPI-5482], percent identity 94 in 339 aa, BLASTP E(): 0.0. (339 aa)
nadDPutative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (201 aa)
mnmA3Putative tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (362 aa)
BF4036tryptophanyl-tRNA synthetase; Similar to gp:AE016942_137 [Bacteroides thetaiotaomicron VPI-5482], percent identity 90 in 361 aa, BLASTP E(): 0.0; Belongs to the class-I aminoacyl-tRNA synthetase family. (363 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (505 aa)
BF4346Putative riboflavin kinase; Similar to gp:AE016936_130 [Bacteroides thetaiotaomicron VPI-5482], percent identity 74 in 314 aa, BLASTP E(): e-134; Belongs to the ribF family. (313 aa)
argSarginyl-tRNA synthetase; Similar to gp:AE016937_169 [Bacteroides thetaiotaomicron VPI-5482], percent identity 92 in 597 aa, BLASTP E(): 0.0. (597 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (654 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (150 aa)
leuSleucyl-tRNA synthetase; Similar to gp:AE016939_36 [Bacteroides thetaiotaomicron VPI-5482], percent identity 87 in 944 aa, BLASTP E(): 0.0; Belongs to the class-I aminoacyl-tRNA synthetase family. (943 aa)
Your Current Organism:
Bacteroides fragilis
NCBI taxonomy Id: 295405
Other names: B. fragilis YCH46, Bacteroides fragilis YCH46, Bacteroides fragilis str. YCH46, Bacteroides fragilis strain YCH46
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