(19 nodes) Mixed, incl. Gap-filling DNA repair synthesis and ligation in GG-NER, and Sensing of DNA Double Strand Breaks network (Micromonas commoda)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MICPUN_56516	FHA domain-containing protein. (480 aa)
	MICPUN_75328	Uncharacterized protein. (390 aa)
	MICPUN_57417	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (525 aa)
	MICPUN_105511	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (867 aa)
	MICPUN_58647	Checkpoint protein; Belongs to the HUS1 family. (321 aa)
	MICPUN_75688	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (392 aa)
	MICPUN_101095	Uncharacterized protein. (250 aa)
	MICPUN_59891	Uncharacterized protein. (642 aa)
	RFC5	AAA domain-containing protein. (355 aa)
	MRE11	Mre11 DNA repair/recombination protein. (894 aa)
	MICPUN_61038	AAA domain-containing protein. (355 aa)
	MICPUN_62284	DRBM domain-containing protein. (514 aa)
	MICPUN_62527	RING-type domain-containing protein. (158 aa)
	MICPUN_95914	AAA domain-containing protein. (329 aa)
	RFC2	Replication factor c, subunit 2. (334 aa)
	MICPUN_114017	Centrosome protein SAS6. (535 aa)
	MICPUN_55160	Uncharacterized protein. (648 aa)
	Rad50	Rad50 DNA repair/recombination protein. (1319 aa)
	MICPUN_77703	Uncharacterized protein. (418 aa)

Your Current Organism:

Micromonas commoda

NCBI taxonomy Id: 296587
Other names: CCMP2709, M. commoda, Micromonas commoda van Baren, Bachy & Worden, 2016, Micromonas pusilla NOUM17, Micromonas pusilla RCC299, Micromonas sp. CCMP1195, Micromonas sp. CCMP1764, Micromonas sp. CCMP492, Micromonas sp. NEPCC29, Micromonas sp. RCC 299, Micromonas sp. RCC299, Micromonas sp. RCC372, Micromonas sp. RCC447, Micromonas sp. RCC448, Micromonas sp. RCC449, Micromonas sp. RCC450, Micromonas sp. RCC472, Micromonas sp. RCC570, Micromonas sp. RCC676, Micromonas sp. RCC803, Micromonas sp. RCC804, Micromonas sp. RCC805, Micromonas sp. RCC808, Micromonas sp. RCC836, RCC299

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MICPUN_101095	MICPUN_105511	C1E8R4	C1E508	Uncharacterized protein.	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	0.991
MICPUN_101095	MICPUN_55160	C1E8R4	C1FDR6	Uncharacterized protein.	Uncharacterized protein.	0.716
MICPUN_101095	MICPUN_56516	C1E8R4	C1DZJ4	Uncharacterized protein.	FHA domain-containing protein.	0.584
MICPUN_101095	MICPUN_57417	C1E8R4	C1E2Z2	Uncharacterized protein.	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	0.897
MICPUN_101095	MICPUN_58647	C1E8R4	C1E6F4	Uncharacterized protein.	Checkpoint protein; Belongs to the HUS1 family.	0.664
MICPUN_101095	MICPUN_59891	C1E8R4	C1E9Z3	Uncharacterized protein.	Uncharacterized protein.	0.476
MICPUN_101095	MICPUN_61038	C1E8R4	C1ED82	Uncharacterized protein.	AAA domain-containing protein.	0.790
MICPUN_101095	MICPUN_62284	C1E8R4	C1EDI7	Uncharacterized protein.	DRBM domain-containing protein.	0.988
MICPUN_101095	MICPUN_62527	C1E8R4	C1EE76	Uncharacterized protein.	RING-type domain-containing protein.	0.423
MICPUN_101095	MICPUN_75328	C1E8R4	C1E259	Uncharacterized protein.	Uncharacterized protein.	0.988
MICPUN_101095	MICPUN_75688	C1E8R4	C1E815	Uncharacterized protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.863
MICPUN_101095	MICPUN_77703	C1E8R4	C1FEZ7	Uncharacterized protein.	Uncharacterized protein.	0.661
MICPUN_101095	MICPUN_95914	C1E8R4	C1EHE2	Uncharacterized protein.	AAA domain-containing protein.	0.789
MICPUN_101095	MRE11	C1E8R4	C1ECB4	Uncharacterized protein.	Mre11 DNA repair/recombination protein.	0.655
MICPUN_101095	RFC2	C1E8R4	C1FD83	Uncharacterized protein.	Replication factor c, subunit 2.	0.788
MICPUN_101095	RFC5	C1E8R4	C1EC47	Uncharacterized protein.	AAA domain-containing protein.	0.740
MICPUN_101095	Rad50	C1E8R4	C1FEP7	Uncharacterized protein.	Rad50 DNA repair/recombination protein.	0.507
MICPUN_105511	MICPUN_101095	C1E508	C1E8R4	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	Uncharacterized protein.	0.991
MICPUN_105511	MICPUN_114017	C1E508	C1FDG9	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	Centrosome protein SAS6.	0.897
MICPUN_105511	MICPUN_55160	C1E508	C1FDR6	Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses.	Uncharacterized protein.	0.797

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