STRINGSTRING
MICPUN_79081 MICPUN_79081 CSD CSD MICPUN_78816 MICPUN_78816 MICPUN_79030 MICPUN_79030 MICPUN_56496 MICPUN_56496 MICPUN_79105 MICPUN_79105 MICPUN_56202 MICPUN_56202 MICPUN_56143 MICPUN_56143 MICPUN_93660 MICPUN_93660 MICPUN_80015 MICPUN_80015 MICPUN_79742 MICPUN_79742 MER3 MER3 TOP6B TOP6B MICPUN_57417 MICPUN_57417 MICPUN_80463 MICPUN_80463 MICPUN_80832 MICPUN_80832 MICPUN_105511 MICPUN_105511 MICPUN_99831 MICPUN_99831 MICPUN_58377 MICPUN_58377 MICPUN_58546 MICPUN_58546 MICPUN_69395 MICPUN_69395 MICPUN_50295 MICPUN_50295 MICPUN_58978 MICPUN_58978 MICPUN_59225 MICPUN_59225 MICPUN_82395 MICPUN_82395 MICPUN_82674 MICPUN_82674 MICPUN_100959 MICPUN_100959 MICPUN_83180 MICPUN_83180 MICPUN_59626 MICPUN_59626 MICPUN_59701 MICPUN_59701 MICPUN_60057 MICPUN_60057 MICPUN_83307 MICPUN_83307 MICPUN_104934 MICPUN_104934 MICPUN_66235 MICPUN_66235 MICPUN_84917 MICPUN_84917 MICPUN_109123 MICPUN_109123 MICPUN_76700 MICPUN_76700 MICPUN_95766 MICPUN_95766 MICPUN_98268 MICPUN_98268 MICPUN_88167 MICPUN_88167 MICPUN_88790 MICPUN_88790 MICPUN_64832 MICPUN_64832 REX REX PRL PRL MCM9 MCM9 TOP1 TOP1 TOP6A TOP6A MCM MCM MICPUN_65906 MICPUN_65906 MICPUN_77461 MICPUN_77461 MICPUN_77343 MICPUN_77343 Rad50 Rad50 MICPUN_83947 MICPUN_83947 MICPUN_84094 MICPUN_84094 MICPUN_60892 MICPUN_60892 MICPUN_62171 MICPUN_62171 MICPUN_85702 MICPUN_85702 MICPUN_86840 MICPUN_86840 MICPUN_87113 MICPUN_87113
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MICPUN_79081DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (861 aa)
CSDCold-shock DNA binding protein. (122 aa)
MICPUN_78816Uncharacterized protein; Belongs to the DEAD box helicase family. (790 aa)
MICPUN_79030DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (639 aa)
MICPUN_56496Helicase ATP-binding domain-containing protein. (797 aa)
MICPUN_79105ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (454 aa)
MICPUN_56202Dead box helicase. (1778 aa)
MICPUN_56143SNF2 super family. (1271 aa)
MICPUN_93660Uncharacterized protein. (959 aa)
MICPUN_80015Uncharacterized protein. (294 aa)
MICPUN_79742DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (703 aa)
MER3DNA helicase Mer3. (1148 aa)
TOP6BDNA topoisomerase 6 subunit B; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. The B subunit binds ATP; Belongs to the TOP6B family. (683 aa)
MICPUN_57417Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (525 aa)
MICPUN_80463HD domain-containing protein. (226 aa)
MICPUN_80832Uncharacterized protein. (880 aa)
MICPUN_105511Replication protein A subunit; Component of the replication protein A complex (RPA) required for DNA recombination, repair and replication. The activity of RPA is mediated by single-stranded DNA binding and protein interactions. Probably involved in repair of double-strand DNA breaks (DSBs) induced by genotoxic stresses. (867 aa)
MICPUN_99831R3H domain-containing protein. (547 aa)
MICPUN_58377DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1459 aa)
MICPUN_58546ATP-dependent DNA helicase. (907 aa)
MICPUN_69395ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (380 aa)
MICPUN_50295Uncharacterized protein. (652 aa)
MICPUN_58978SNF2 super family. (712 aa)
MICPUN_59225SNF2 super family. (1345 aa)
MICPUN_82395Uncharacterized protein. (481 aa)
MICPUN_82674Uncharacterized protein. (597 aa)
MICPUN_100959AAA_11 domain-containing protein. (594 aa)
MICPUN_83180Cold-shock protein with RNA binding domain. (305 aa)
MICPUN_59626Helicase ATP-binding domain-containing protein. (1566 aa)
MICPUN_59701DNA topoisomerase I. (1227 aa)
MICPUN_60057Ku domain-containing protein. (715 aa)
MICPUN_83307MCM domain-containing protein; Belongs to the MCM family. (786 aa)
MICPUN_104934SNF2 super family. (1999 aa)
MICPUN_66235Uncharacterized protein. (531 aa)
MICPUN_84917DNA helicase; Belongs to the MCM family. (770 aa)
MICPUN_109123RuvB-like helicase; Belongs to the RuvB family. (421 aa)
MICPUN_76700AAA_12 domain-containing protein. (53 aa)
MICPUN_95766DNA helicase; Belongs to the MCM family. (817 aa)
MICPUN_98268RuvB-like helicase; Belongs to the RuvB family. (466 aa)
MICPUN_88167TOP4c domain-containing protein. (963 aa)
MICPUN_88790Helicase ATP-binding domain-containing protein. (644 aa)
MICPUN_64832SAP domain-containing protein. (310 aa)
REXExonuclease and DNA helicase. (1473 aa)
PRLDNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (747 aa)
MCM9Minichromosome maintenance protein; Belongs to the MCM family. (794 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (635 aa)
TOP6ADNA topoisomerase 6 subunit A; Component of the DNA topoisomerase VI involved in chromatin organization and progression of endoreduplication cycles. Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (391 aa)
MCMDNA helicase; Belongs to the MCM family. (907 aa)
MICPUN_65906Uncharacterized protein. (570 aa)
MICPUN_77461DNA helicase; Belongs to the MCM family. (658 aa)
MICPUN_77343Uncharacterized protein. (809 aa)
Rad50Rad50 DNA repair/recombination protein. (1319 aa)
MICPUN_83947Uncharacterized protein. (622 aa)
MICPUN_84094Uncharacterized protein. (1901 aa)
MICPUN_60892SAP domain-containing protein. (780 aa)
MICPUN_62171Uncharacterized protein. (303 aa)
MICPUN_85702Helicase ATP-binding domain-containing protein. (915 aa)
MICPUN_86840DNA helicase; Belongs to the MCM family. (833 aa)
MICPUN_87113Uncharacterized protein. (592 aa)
Your Current Organism:
Micromonas commoda
NCBI taxonomy Id: 296587
Other names: CCMP2709, M. commoda, Micromonas commoda van Baren, Bachy & Worden, 2016, Micromonas pusilla NOUM17, Micromonas pusilla RCC299, Micromonas sp. CCMP1195, Micromonas sp. CCMP1764, Micromonas sp. CCMP492, Micromonas sp. NEPCC29, Micromonas sp. RCC 299, Micromonas sp. RCC299, Micromonas sp. RCC372, Micromonas sp. RCC447, Micromonas sp. RCC448, Micromonas sp. RCC449, Micromonas sp. RCC450, Micromonas sp. RCC472, Micromonas sp. RCC570, Micromonas sp. RCC676, Micromonas sp. RCC803, Micromonas sp. RCC804, Micromonas sp. RCC805, Micromonas sp. RCC808, Micromonas sp. RCC836, RCC299
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.