STRINGSTRING
nuoN nuoN nuoM nuoM nuoL nuoL nuoK nuoK nuoH nuoH nqo3 nqo3 gltA2 gltA2 mdh mdh aceB aceB SIS35893.1 SIS35893.1 cooF cooF sucB_1 sucB_1 sucA sucA icd icd SIS32288.1 SIS32288.1 cydA_2 cydA_2 cydB cydB aspA aspA ppc_1 ppc_1 sucC sucC SIS39682.1 SIS39682.1 sucD sucD fumC fumC SIS45032.1 SIS45032.1 acn acn acnB acnB mqo1 mqo1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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nuoNNADH-quinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (461 aa)
nuoMNADH dehydrogenase subunit M. (497 aa)
nuoLNADH-quinone oxidoreductase subunit L. (637 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (109 aa)
nuoHNADH dehydrogenase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (354 aa)
nqo3NADH dehydrogenase subunit G. (332 aa)
gltA2Citrate synthase; Belongs to the citrate synthase family. (428 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (308 aa)
aceBMalate synthase; Belongs to the malate synthase family. (525 aa)
SIS35893.1Quinol:cytochrome c oxidoreductase quinone-binding subunit 1. (465 aa)
cooFProkaryotic molybdopterin-containing oxidoreductase family, iron-sulfur binding subunit. (1021 aa)
sucB_12-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (418 aa)
sucA2-oxoglutarate dehydrogenase E1 component. (938 aa)
icdIsocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (739 aa)
SIS32288.1Protein of unknown function. (290 aa)
cydA_2Cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein. (447 aa)
cydBCytochrome bd-I ubiquinol oxidase subunit 2 apoprotein. (334 aa)
aspAAspartate ammonia-lyase. (466 aa)
ppc_1Phosphoenolpyruvate carboxylase, type 1; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (863 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
SIS39682.1Cytochrome c oxidase cbb3-type subunit I/II; Belongs to the heme-copper respiratory oxidase family. (759 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
fumCFumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
SIS45032.1Cytochrome c oxidase cbb3-type subunit I/II; Belongs to the heme-copper respiratory oxidase family. (753 aa)
acnAconitase. (755 aa)
acnBAconitase. (926 aa)
mqo1Malate dehydrogenase (quinone). (524 aa)
Your Current Organism:
Chryseobacterium shigense
NCBI taxonomy Id: 297244
Other names: C. shigense, Chryseobacterium shigense Shimomura et al. 2005 emend. Montero-Calasanz et al. 2014, Chryseobacterium sp. 1107B-08, Chryseobacterium sp. 628-2-08, Chryseobacterium sp. 664-09, Chryseobacterium sp. 972B-08, DSM 17126, NCIMB 14047, strain GUM-Kaji
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