STRINGSTRING
camB camB bioB bioB bioA bioA SIS28492.1 SIS28492.1 SIS28819.1 SIS28819.1 SIS28072.1 SIS28072.1 leuC_2 leuC_2 rlmN rlmN SIS32535.1 SIS32535.1 SIS32551.1 SIS32551.1 ilvD_2 ilvD_2 sdaA sdaA queG queG mutY mutY lipA_2 lipA_2 hemN_1 hemN_1 thcC thcC SIS33921.1 SIS33921.1 SIS34578.1 SIS34578.1 SIS34699.1 SIS34699.1 cooF cooF iscA iscA SIS35920.1 SIS35920.1 SIS35996.1 SIS35996.1 cysI cysI nth nth SIS34806.1 SIS34806.1 rimO rimO SIS38553.1 SIS38553.1 SIS39065.1 SIS39065.1 nadA nadA frdB_2 frdB_2 SIS39481.1 SIS39481.1 SIS39493.1 SIS39493.1 SIS37284.1 SIS37284.1 minD minD rlmCD_2 rlmCD_2 frdB_1 frdB_1 miaB_2 miaB_2 fumA fumA queE queE SIS44893.1 SIS44893.1 SIS44902.1 SIS44902.1 yccM yccM thiC_2 thiC_2 thiH thiH acn acn acnB acnB SIS43993.1 SIS43993.1 miaB_1 miaB_1 gltB gltB hemN_2 hemN_2 nqo9 nqo9 nqo3 nqo3 nqo1 nqo1 nqo2 nqo2 nqo6 nqo6 fdx_1 fdx_1 fdx_2 fdx_2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
camBFerredoxin, 2Fe-2S. (109 aa)
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (331 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
SIS28492.1Hypothetical protein. (422 aa)
SIS28819.1Radical SAM superfamily enzyme YgiQ, UPF0313 family. (735 aa)
SIS28072.1Hypothetical protein. (514 aa)
leuC_23-isopropylmalate/(R)-2-methylmalate dehydratase large subunit. (462 aa)
rlmN23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (344 aa)
SIS32535.1Cytochrome c oxidase accessory protein FixG. (480 aa)
SIS32551.1TIGR02757 family protein. (256 aa)
ilvD_2Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (563 aa)
sdaAL-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (472 aa)
queGEpoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (317 aa)
mutYA/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. (345 aa)
lipA_2Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (288 aa)
hemN_1Oxygen-independent coproporphyrinogen-3 oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (452 aa)
thcCFerredoxin, 2Fe-2S. (109 aa)
SIS33921.1SPASM domain peptide maturase, grasp-with-spasm system. (359 aa)
SIS34578.1SPASM domain peptide maturase, grasp-with-spasm system. (332 aa)
SIS34699.1Hypothetical protein. (151 aa)
cooFProkaryotic molybdopterin-containing oxidoreductase family, iron-sulfur binding subunit. (1021 aa)
iscAIron-sulfur cluster assembly protein; Belongs to the HesB/IscA family. (109 aa)
SIS35920.1Hypothetical protein. (162 aa)
SIS35996.1FeS assembly SUF system protein. (108 aa)
cysISulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (557 aa)
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (206 aa)
SIS34806.1ring-1,2-phenylacetyl-CoA epoxidase subunit PaaD. (160 aa)
rimOSSU ribosomal protein S12P methylthiotransferase; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (433 aa)
SIS38553.1SPASM domain peptide maturase, grasp-with-spasm system. (336 aa)
SIS39065.1Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain. (292 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (351 aa)
frdB_2Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (249 aa)
SIS39481.1Putative DNA modification/repair radical SAM protein. (419 aa)
SIS39493.1Probable DNA metabolism protein. (252 aa)
SIS37284.1Fe-S cluster biogenesis protein NfuA, 4Fe-4S-binding domain. (82 aa)
minDATP-binding protein involved in chromosome partitioning; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa)
rlmCD_223S rRNA m(5)U-1939 methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (468 aa)
frdB_1Succinate dehydrogenase / fumarate reductase iron-sulfur subunit. (255 aa)
miaB_2tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (481 aa)
fumAFumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (535 aa)
queEOrganic radical activating enzyme; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (209 aa)
SIS44893.14Fe-4S dicluster domain-containing protein. (447 aa)
SIS44902.1Cysteine-rich domain-containing protein. (261 aa)
yccMCytochrome c oxidase accessory protein FixG. (484 aa)
thiC_2Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. (603 aa)
thiHTyrosine lyase ThiH. (372 aa)
acnAconitase. (755 aa)
acnBAconitase. (926 aa)
SIS43993.1DNA repair photolyase. (351 aa)
miaB_1Threonylcarbamoyladenosine tRNA methylthiotransferase MtaB. (448 aa)
gltBGlutamate synthase domain-containing protein 2; Belongs to the glutamate synthase family. (505 aa)
hemN_2Oxygen-independent coproporphyrinogen-3 oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (384 aa)
nqo9NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (185 aa)
nqo3NADH dehydrogenase subunit G. (332 aa)
nqo1NADH dehydrogenase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (452 aa)
nqo2NADH dehydrogenase subunit E. (169 aa)
nqo6NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (186 aa)
fdx_14Fe-4S binding domain-containing protein. (116 aa)
fdx_24Fe-4S dicluster domain-containing protein. (115 aa)
Your Current Organism:
Chryseobacterium shigense
NCBI taxonomy Id: 297244
Other names: C. shigense, Chryseobacterium shigense Shimomura et al. 2005 emend. Montero-Calasanz et al. 2014, Chryseobacterium sp. 1107B-08, Chryseobacterium sp. 628-2-08, Chryseobacterium sp. 664-09, Chryseobacterium sp. 972B-08, DSM 17126, NCIMB 14047, strain GUM-Kaji
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