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pdhB pdhB SIS38383.1 SIS38383.1 SIS36225.1 SIS36225.1 accD_2 accD_2 fadI fadI bacD bacD yqhD_1 yqhD_1 lpd_2 lpd_2 acsA acsA acs acs bfmBAB_2 bfmBAB_2 lpd_1 lpd_1 SIS29363.1 SIS29363.1 SIS29219.1 SIS29219.1 mutB_1 mutB_1 thlA thlA SIS56250.1 SIS56250.1 SIS47594.1 SIS47594.1 acnB acnB mutB_2 mutB_2 yfeX yfeX sucD sucD scpA_1 scpA_1 accA accA accC accC accB accB sucC sucC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
pdhBPyruvate/2-oxoglutarate/acetoin dehydrogenase complex, dehydrogenase (E1) component. (810 aa)
SIS38383.1Putative signal transducing protein. (133 aa)
SIS36225.1Muramoyltetrapeptide carboxypeptidase. (309 aa)
accD_2acetyl-CoA carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (284 aa)
fadI3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
bacDBiotin carboxylase. (381 aa)
yqhD_1NADP-dependent alcohol dehydrogenase. (387 aa)
lpd_2Dihydrolipoamide dehydrogenase. (466 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (635 aa)
acspropionyl-CoA synthetase. (628 aa)
bfmBAB_22-oxoisovalerate dehydrogenase E1 component. (699 aa)
lpd_1Dihydrolipoamide dehydrogenase. (462 aa)
SIS29363.1Dihydrolipoamide dehydrogenase. (467 aa)
SIS29219.1Hypothetical protein. (403 aa)
mutB_1methylmalonyl-CoA mutase. (387 aa)
thlAacetyl-CoA C-acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
SIS56250.1Hypothetical protein. (127 aa)
SIS47594.1methylmalonyl-CoA epimerase. (132 aa)
acnBAconitase. (926 aa)
mutB_2Heterodimeric methylmalonyl-CoA mutase large subunit precursor. (706 aa)
yfeXPutative iron-dependent peroxidase. (311 aa)
sucDsuccinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
scpA_1methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1115 aa)
accAacetyl-CoA carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
accBacetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (159 aa)
sucCsuccinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
Your Current Organism:
Chryseobacterium shigense
NCBI taxonomy Id: 297244
Other names: C. shigense, Chryseobacterium shigense Shimomura et al. 2005 emend. Montero-Calasanz et al. 2014, Chryseobacterium sp. 1107B-08, Chryseobacterium sp. 628-2-08, Chryseobacterium sp. 664-09, Chryseobacterium sp. 972B-08, DSM 17126, NCIMB 14047, strain GUM-Kaji
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