74 items (Penicillium vulpinum) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6QZM5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
	A0A1V6R3J9	Uncharacterized protein. (510 aa)
	A0A1V6R3Z0	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	A0A1V6R4N7	Uncharacterized protein. (392 aa)
	A0A1V6R7F8	Chorismate_bind domain-containing protein. (437 aa)
	A0A1V6R9E6	Aminotran_1_2 domain-containing protein. (536 aa)
	A0A1V6RBG1	Meth_synt_2 domain-containing protein. (402 aa)
	A0A1V6RBT3	MYND-type domain-containing protein. (893 aa)
	A0A1V6RDQ9	AP_endonuc_2 domain-containing protein. (384 aa)
	A0A1V6RDR5	Uncharacterized protein. (307 aa)
	A0A1V6RED5	Aminotran_1_2 domain-containing protein. (433 aa)
	A0A1V6RER5	Uncharacterized protein. (959 aa)
	A0A1V6RFV9	PALP domain-containing protein. (400 aa)
	A0A1V6RG45	Uncharacterized protein. (594 aa)
	A0A1V6RLX7	PRA-CH domain-containing protein. (927 aa)
	A0A1V6RM11	Uncharacterized protein. (361 aa)
	A0A1V6RMP2	Meth_synt_2 domain-containing protein. (408 aa)
	A0A1V6RMT9	Uncharacterized protein. (385 aa)
	A0A1V6RMU9	AMP_N domain-containing protein. (496 aa)
	A0A1V6RNJ3	Uncharacterized protein. (484 aa)
	A0A1V6RRV6	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (520 aa)
	A0A1V6RSB8	AMP_N domain-containing protein. (465 aa)
	A0A1V6RSF5	Tryptophan synthase. (694 aa)
	A0A1V6RSP6	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (423 aa)
	A0A1V6RU21	Aminotran_1_2 domain-containing protein. (403 aa)
	A0A1V6RUH4	Uncharacterized protein. (75 aa)
	A0A1V6RUL2	Uncharacterized protein. (244 aa)
	A0A1V6RUX8	Uncharacterized protein. (249 aa)
	A0A1V6RV07	AP_endonuc_2 domain-containing protein. (361 aa)
	A0A1V6RVB6	PALP domain-containing protein. (511 aa)
	A0A1V6RVE5	Uncharacterized protein. (399 aa)
	A0A1V6RWA3	Uncharacterized protein. (768 aa)
	A0A1V6RX02	Uncharacterized protein; Belongs to the PAL/histidase family. (686 aa)
	A0A1V6RX37	Aminotran_1_2 domain-containing protein. (435 aa)
	A0A1V6RYH0	Aminotran_1_2 domain-containing protein. (543 aa)
	A0A1V6RYL1	Aminotran_5 domain-containing protein. (446 aa)
	A0A1V6RZK1	Adenosylhomocysteinase. (448 aa)
	A0A1V6S003	Cysteine dioxygenase. (215 aa)
	A0A1V6S037	FtsJ domain-containing protein. (346 aa)
	A0A1V6S049	PALP domain-containing protein. (430 aa)
	A0A1V6S0G5	Uncharacterized protein. (400 aa)
	A0A1V6S1P4	Tryptophan synthase. (723 aa)
	A0A1V6S226	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (753 aa)
	A0A1V6S280	4-hydroxyphenylpyruvate dioxygenase. (404 aa)
	A0A1V6S2G9	Chorismate synthase. (404 aa)
	A0A1V6S2I5	Uncharacterized protein. (449 aa)
	A0A1V6S2T6	Aminotran_1_2 domain-containing protein. (408 aa)
	A0A1V6S3E1	Aspartokinase. (518 aa)
	A0A1V6S3T6	Uncharacterized protein. (317 aa)
	A0A1V6S416	Uncharacterized protein. (353 aa)
	A0A1V6S425	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (463 aa)
	A0A1V6S521	Uncharacterized protein. (513 aa)
	A0A1V6S593	Semialdhyde_dh domain-containing protein. (364 aa)
	A0A1V6S6E3	Uncharacterized protein. (475 aa)
	A0A1V6S791	Uncharacterized protein. (316 aa)
	A0A1V6S7G1	Uncharacterized protein. (441 aa)
	A0A1V6S7I3	Uncharacterized protein. (537 aa)
	A0A1V6S7I5	Beta_elim_lyase domain-containing protein. (364 aa)
	A0A1V6S8I4	Uncharacterized protein. (760 aa)
	A0A1V6S8J8	4-hydroxyphenylpyruvate dioxygenase. (407 aa)
	A0A1V6S8U8	Uncharacterized protein. (285 aa)
	A0A1V6S8W0	Shikimate_dh_N domain-containing protein. (308 aa)
	A0A1V6S8X4	Chorismate mutase. (296 aa)
	A0A1V6S9X5	Uncharacterized protein. (320 aa)
	A0A1V6SAY7	Cysteine dioxygenase. (215 aa)
	A0A1V6SBC4	Meth_synt_2 domain-containing protein. (402 aa)
	A0A1V6SBP2	Uncharacterized protein. (436 aa)
	A0A1V6SC64	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (310 aa)
	A0A1V6SEH4	AB hydrolase-1 domain-containing protein. (499 aa)
	A0A1V6SEV4	Uncharacterized protein. (437 aa)
	A0A1V6SF61	Uncharacterized protein. (239 aa)
	A0A1V6SF85	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (266 aa)
	A0A1V6SFD2	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	A0A1V6SFI2	Hcy-binding domain-containing protein. (345 aa)

Your Current Organism:

Penicillium vulpinum

NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6QZM5	A0A1V6R7F8	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Chorismate_bind domain-containing protein.	0.428
A0A1V6QZM5	A0A1V6RBT3	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	MYND-type domain-containing protein.	0.500
A0A1V6QZM5	A0A1V6RED5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Aminotran_1_2 domain-containing protein.	0.989
A0A1V6QZM5	A0A1V6RER5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.970
A0A1V6QZM5	A0A1V6RLX7	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	PRA-CH domain-containing protein.	0.995
A0A1V6QZM5	A0A1V6RSF5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Tryptophan synthase.	0.778
A0A1V6QZM5	A0A1V6RUL2	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.993
A0A1V6QZM5	A0A1V6RVB6	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	PALP domain-containing protein.	0.778
A0A1V6QZM5	A0A1V6S1P4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Tryptophan synthase.	0.778
A0A1V6QZM5	A0A1V6S226	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.	0.944
A0A1V6QZM5	A0A1V6S2G9	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Chorismate synthase.	0.428
A0A1V6QZM5	A0A1V6S3E1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Aspartokinase.	0.739
A0A1V6QZM5	A0A1V6S521	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.428
A0A1V6QZM5	A0A1V6S593	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Semialdhyde_dh domain-containing protein.	0.439
A0A1V6QZM5	A0A1V6S6E3	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.931
A0A1V6QZM5	A0A1V6S7G1	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.595
A0A1V6QZM5	A0A1V6S8X4	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Chorismate mutase.	0.523
A0A1V6QZM5	A0A1V6S9X5	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Uncharacterized protein.	0.991
A0A1V6QZM5	A0A1V6SC64	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily.	0.604
A0A1V6QZM5	A0A1V6SF85	Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.994