(18 nodes) SCF ubiquitin ligase complex, and Protein neddylation network (Penicillium vulpinum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	A0A1V6R5J0	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme. (560 aa)
	A0A1V6R6Z1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
	A0A1V6R9K4	CULLIN_2 domain-containing protein; Belongs to the cullin family. (842 aa)
	A0A1V6RCP1	E2_bind domain-containing protein. (434 aa)
	A0A1V6RDW6	Uncharacterized protein. (666 aa)
	A0A1V6RFW8	TIP120 domain-containing protein. (1035 aa)
	A0A1V6RGR3	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (101 aa)
	A0A1V6RI89	CULLIN_2 domain-containing protein; Belongs to the cullin family. (824 aa)
	A0A1V6RRQ0	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. (269 aa)
	A0A1V6RXS9	Uncharacterized protein. (215 aa)
	A0A1V6S0Q2	Uncharacterized protein. (924 aa)
	A0A1V6S3I2	Uncharacterized protein; Belongs to the SKP1 family. (159 aa)
	A0A1V6S3M5	RING-type domain-containing protein. (117 aa)
	A0A1V6S4U4	Uncharacterized protein. (1085 aa)
	A0A1V6S4X4	WD_REPEATS_REGION domain-containing protein. (392 aa)
	A0A1V6S798	Uncharacterized protein. (1398 aa)
	A0A1V6S8Y1	Uncharacterized protein. (592 aa)
	A0A1V6S9S2	Uncharacterized protein. (705 aa)

Your Current Organism:

Penicillium vulpinum

NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6R5J0	A0A1V6R6Z1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.979
A0A1V6R5J0	A0A1V6R9K4	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.816
A0A1V6R5J0	A0A1V6RCP1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	E2_bind domain-containing protein.	0.999
A0A1V6R5J0	A0A1V6RDW6	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.706
A0A1V6R5J0	A0A1V6RGR3	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Skp1_POZ domain-containing protein; Belongs to the SKP1 family.	0.680
A0A1V6R5J0	A0A1V6RI89	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.816
A0A1V6R5J0	A0A1V6RRQ0	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Defective in cullin neddylation protein; Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.	0.769
A0A1V6R5J0	A0A1V6RXS9	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.727
A0A1V6R5J0	A0A1V6S0Q2	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.636
A0A1V6R5J0	A0A1V6S3I2	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein; Belongs to the SKP1 family.	0.729
A0A1V6R5J0	A0A1V6S3M5	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	RING-type domain-containing protein.	0.803
A0A1V6R5J0	A0A1V6S4U4	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.715
A0A1V6R5J0	A0A1V6S4X4	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	WD_REPEATS_REGION domain-containing protein.	0.715
A0A1V6R5J0	A0A1V6S798	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.978
A0A1V6R5J0	A0A1V6S8Y1	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.625
A0A1V6R5J0	A0A1V6S9S2	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	Uncharacterized protein.	0.622
A0A1V6R6Z1	A0A1V6R5J0	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-ULA1 E1 enzyme.	0.979
A0A1V6R6Z1	A0A1V6R9K4	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.949
A0A1V6R6Z1	A0A1V6RCP1	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E2_bind domain-containing protein.	0.983
A0A1V6R6Z1	A0A1V6RDW6	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.629