(24 nodes) Preribosome, large subunit precursor, and 5S rRNA binding network (Penicillium vulpinum)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	A0A1V6R3P4	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (727 aa)
	A0A1V6RFD2	Brix domain-containing protein. (361 aa)
	A0A1V6RMR5	Uncharacterized protein; Belongs to the DEAD box helicase family. (709 aa)
	A0A1V6RMU5	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (653 aa)
	A0A1V6RSB5	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (688 aa)
	A0A1V6RSG9	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (184 aa)
	A0A1V6RTG5	Protein MAK16; Belongs to the MAK16 family. (319 aa)
	A0A1V6RV49	CP-type G domain-containing protein. (541 aa)
	A0A1V6RWW5	Uncharacterized protein. (766 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (767 aa)
	A0A1V6S0F1	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (246 aa)
	A0A1V6S1M7	TRASH domain-containing protein. (190 aa)
	A0A1V6S1V4	Uncharacterized protein. (316 aa)
	A0A1V6S480	RNA helicase. (607 aa)
	A0A1V6S4Z7	RRM domain-containing protein. (469 aa)
	A0A1V6S506	Brix domain-containing protein. (431 aa)
	A0A1V6S6S8	Uncharacterized protein. (234 aa)
	A0A1V6S6T9	Uncharacterized protein. (261 aa)
	A0A1V6S6V9	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (433 aa)
	A0A1V6S8D2	Uncharacterized protein. (360 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (818 aa)
	A0A1V6SBS4	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (562 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (675 aa)
	A0A1V6SER7	Uncharacterized protein. (398 aa)

Your Current Organism:

Penicillium vulpinum

NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1V6R3P4	A0A1V6RFD2	A0A1V6R3P4	A0A1V6RFD2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Brix domain-containing protein.	0.988
A0A1V6R3P4	A0A1V6RMR5	A0A1V6R3P4	A0A1V6RMR5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.958
A0A1V6R3P4	A0A1V6RMU5	A0A1V6R3P4	A0A1V6RMU5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.996
A0A1V6R3P4	A0A1V6RSB5	A0A1V6R3P4	A0A1V6RSB5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.992
A0A1V6R3P4	A0A1V6RSG9	A0A1V6R3P4	A0A1V6RSG9	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.998
A0A1V6R3P4	A0A1V6RTG5	A0A1V6R3P4	A0A1V6RTG5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Protein MAK16; Belongs to the MAK16 family.	0.975
A0A1V6R3P4	A0A1V6RV49	A0A1V6R3P4	A0A1V6RV49	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	CP-type G domain-containing protein.	0.996
A0A1V6R3P4	A0A1V6RWW5	A0A1V6R3P4	A0A1V6RWW5	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.996
A0A1V6R3P4	A0A1V6S0F1	A0A1V6R3P4	A0A1V6S0F1	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.992
A0A1V6R3P4	A0A1V6S1M7	A0A1V6R3P4	A0A1V6S1M7	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	TRASH domain-containing protein.	0.990
A0A1V6R3P4	A0A1V6S1V4	A0A1V6R3P4	A0A1V6S1V4	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.989
A0A1V6R3P4	A0A1V6S480	A0A1V6R3P4	A0A1V6S480	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	RNA helicase.	0.995
A0A1V6R3P4	A0A1V6S4Z7	A0A1V6R3P4	A0A1V6S4Z7	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	RRM domain-containing protein.	0.993
A0A1V6R3P4	A0A1V6S506	A0A1V6R3P4	A0A1V6S506	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Brix domain-containing protein.	0.982
A0A1V6R3P4	A0A1V6S6S8	A0A1V6R3P4	A0A1V6S6S8	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.940
A0A1V6R3P4	A0A1V6S6T9	A0A1V6R3P4	A0A1V6S6T9	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.956
A0A1V6R3P4	A0A1V6S6V9	A0A1V6R3P4	A0A1V6S6V9	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family.	0.863
A0A1V6R3P4	A0A1V6S8D2	A0A1V6R3P4	A0A1V6S8D2	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.993
A0A1V6R3P4	A0A1V6SBS4	A0A1V6R3P4	A0A1V6SBS4	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.953
A0A1V6R3P4	A0A1V6SER7	A0A1V6R3P4	A0A1V6SER7	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.995