STRINGSTRING
A0A1V6R257 A0A1V6R257 A0A1V6R5D7 A0A1V6R5D7 A0A1V6R665 A0A1V6R665 A0A1V6R7F3 A0A1V6R7F3 A0A1V6R8N4 A0A1V6R8N4 MCM7 MCM7 A0A1V6RDJ6 A0A1V6RDJ6 A0A1V6RDP5 A0A1V6RDP5 A0A1V6RDX6 A0A1V6RDX6 A0A1V6RE98 A0A1V6RE98 A0A1V6RES2 A0A1V6RES2 A0A1V6REY5 A0A1V6REY5 A0A1V6RFC2 A0A1V6RFC2 A0A1V6RFL5 A0A1V6RFL5 A0A1V6RFT0 A0A1V6RFT0 A0A1V6RFZ9 A0A1V6RFZ9 A0A1V6RG18 A0A1V6RG18 A0A1V6RG43 A0A1V6RG43 A0A1V6RG56 A0A1V6RG56 FEN1 FEN1 A0A1V6RG81 A0A1V6RG81 A0A1V6RGG9 A0A1V6RGG9 A0A1V6RGT5 A0A1V6RGT5 A0A1V6RHC9 A0A1V6RHC9 SLX1 SLX1 A0A1V6RHF1 A0A1V6RHF1 A0A1V6RJD1 A0A1V6RJD1 A0A1V6RN65 A0A1V6RN65 A0A1V6RN72 A0A1V6RN72 A0A1V6RNF7 A0A1V6RNF7 A0A1V6RRP0 A0A1V6RRP0 A0A1V6RS54 A0A1V6RS54 A0A1V6RS92 A0A1V6RS92 A0A1V6RSF6 A0A1V6RSF6 A0A1V6RSI9 A0A1V6RSI9 A0A1V6RSJ4 A0A1V6RSJ4 A0A1V6RSL3 A0A1V6RSL3 A0A1V6RSP1 A0A1V6RSP1 A0A1V6RT13 A0A1V6RT13 A0A1V6RTI0 A0A1V6RTI0 A0A1V6RTJ3 A0A1V6RTJ3 A0A1V6RTT5 A0A1V6RTT5 A0A1V6RU55 A0A1V6RU55 A0A1V6RUW9 A0A1V6RUW9 A0A1V6RV33 A0A1V6RV33 A0A1V6RV82 A0A1V6RV82 A0A1V6RVE7 A0A1V6RVE7 A0A1V6RVP7 A0A1V6RVP7 A0A1V6RVS4 A0A1V6RVS4 A0A1V6RW39 A0A1V6RW39 A0A1V6RWJ3 A0A1V6RWJ3 A0A1V6RXG8 A0A1V6RXG8 A0A1V6RY93 A0A1V6RY93 A0A1V6RYF8 A0A1V6RYF8 A0A1V6RYP8 A0A1V6RYP8 A0A1V6RYX3 A0A1V6RYX3 A0A1V6RZ27 A0A1V6RZ27 A0A1V6RZ32 A0A1V6RZ32 A0A1V6RZR4 A0A1V6RZR4 A0A1V6S023 A0A1V6S023 A0A1V6S0C7 A0A1V6S0C7 A0A1V6S0F3 A0A1V6S0F3 A0A1V6S0H8 A0A1V6S0H8 A0A1V6S0I3 A0A1V6S0I3 A0A1V6S0V8 A0A1V6S0V8 A0A1V6S0Y2 A0A1V6S0Y2 A0A1V6S128 A0A1V6S128 A0A1V6S1R3 A0A1V6S1R3 A0A1V6S2J1 A0A1V6S2J1 A0A1V6S2N9 A0A1V6S2N9 A0A1V6S318 A0A1V6S318 A0A1V6S3F4 A0A1V6S3F4 A0A1V6S4F4 A0A1V6S4F4 A0A1V6S4H2 A0A1V6S4H2 A0A1V6S4M2 A0A1V6S4M2 A0A1V6S4S6 A0A1V6S4S6 A0A1V6S5C6 A0A1V6S5C6 A0A1V6S5K3 A0A1V6S5K3 A0A1V6S5N5 A0A1V6S5N5 A0A1V6S5Q0 A0A1V6S5Q0 A0A1V6S5W2 A0A1V6S5W2 A0A1V6S6D5 A0A1V6S6D5 A0A1V6S6G7 A0A1V6S6G7 A0A1V6S6K3 A0A1V6S6K3 A0A1V6S6X9 A0A1V6S6X9 A0A1V6S736 A0A1V6S736 A0A1V6S795 A0A1V6S795 A0A1V6S7D3 A0A1V6S7D3 A0A1V6S7T2 A0A1V6S7T2 A0A1V6S819 A0A1V6S819 A0A1V6S8C0 A0A1V6S8C0 A0A1V6S8V5 A0A1V6S8V5 A0A1V6S8X9 A0A1V6S8X9 A0A1V6S994 A0A1V6S994 A0A1V6S9K8 A0A1V6S9K8 A0A1V6SA09 A0A1V6SA09 A0A1V6SAH1 A0A1V6SAH1 A0A1V6SBH6 A0A1V6SBH6 A0A1V6SBK3 A0A1V6SBK3 A0A1V6SBX2 A0A1V6SBX2 A0A1V6SCE3 A0A1V6SCE3 A0A1V6SCG3 A0A1V6SCG3 A0A1V6SCK9 A0A1V6SCK9 A0A1V6SD43 A0A1V6SD43 A0A1V6SDH8 A0A1V6SDH8 A0A1V6SDV2 A0A1V6SDV2 A0A1V6SE62 A0A1V6SE62 A0A1V6SEL8 A0A1V6SEL8 A0A1V6SEP6 A0A1V6SEP6 A0A1V6SG70 A0A1V6SG70
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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A0A1V6R257Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
A0A1V6R5D7AAA_16 domain-containing protein. (529 aa)
A0A1V6R665Rad51 domain-containing protein. (367 aa)
A0A1V6R7F3WD_REPEATS_REGION domain-containing protein. (839 aa)
A0A1V6R8N4SAE2 domain-containing protein. (685 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (812 aa)
A0A1V6RDJ6DNA helicase; Belongs to the MCM family. (896 aa)
A0A1V6RDP5DRMBL domain-containing protein. (844 aa)
A0A1V6RDX6UmuC domain-containing protein. (628 aa)
A0A1V6RE98DNA_MISMATCH_REPAIR_2 domain-containing protein. (1006 aa)
A0A1V6RES2CHY-type domain-containing protein. (122 aa)
A0A1V6REY5Uncharacterized protein. (607 aa)
A0A1V6RFC2AAA domain-containing protein. (352 aa)
A0A1V6RFL5DNA_pol_E_B domain-containing protein. (757 aa)
A0A1V6RFT0AA_TRNA_LIGASE_II domain-containing protein. (577 aa)
A0A1V6RFZ9Uncharacterized protein. (184 aa)
A0A1V6RG18Uncharacterized protein. (451 aa)
A0A1V6RG43ORC_WH_C domain-containing protein. (697 aa)
A0A1V6RG56DNA_MISMATCH_REPAIR_2 domain-containing protein. (886 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (395 aa)
A0A1V6RG81Replication factor C subunit 1. (1055 aa)
A0A1V6RGG9DNA helicase; Belongs to the MCM family. (954 aa)
A0A1V6RGT5Protein kinase domain-containing protein. (478 aa)
A0A1V6RHC9DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (271 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (401 aa)
A0A1V6RHF1DNA helicase; Belongs to the MCM family. (719 aa)
A0A1V6RJD1Uncharacterized protein. (1004 aa)
A0A1V6RN65Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (781 aa)
A0A1V6RN72Uncharacterized protein. (848 aa)
A0A1V6RNF7RPA_C domain-containing protein. (280 aa)
A0A1V6RRP0DNA polymerase. (1104 aa)
A0A1V6RS54BRCT domain-containing protein. (341 aa)
A0A1V6RS92DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (444 aa)
A0A1V6RSF6Uncharacterized protein. (310 aa)
A0A1V6RSI9Uncharacterized protein. (446 aa)
A0A1V6RSJ4DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
A0A1V6RSL3Checkpoint protein; Belongs to the HUS1 family. (343 aa)
A0A1V6RSP1DNA polymerase. (1461 aa)
A0A1V6RT13Uncharacterized protein. (1103 aa)
A0A1V6RTI0Zn(2)-C6 fungal-type domain-containing protein. (444 aa)
A0A1V6RTJ3Uncharacterized protein. (396 aa)
A0A1V6RTT5HORMA domain-containing protein. (298 aa)
A0A1V6RU55DNA_MISMATCH_REPAIR_2 domain-containing protein. (938 aa)
A0A1V6RUW9Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (786 aa)
A0A1V6RV33CBFD_NFYB_HMF domain-containing protein. (272 aa)
A0A1V6RV82Uncharacterized protein. (1501 aa)
A0A1V6RVE7DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1161 aa)
A0A1V6RVP7Zf-primase domain-containing protein. (771 aa)
A0A1V6RVS4Uncharacterized protein; Belongs to the RecA family. (338 aa)
A0A1V6RW39ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (510 aa)
A0A1V6RWJ3DNA ligase. (821 aa)
A0A1V6RXG8AAA domain-containing protein. (1187 aa)
A0A1V6RY93Zn(2)-C6 fungal-type domain-containing protein. (806 aa)
A0A1V6RYF8Uncharacterized protein. (738 aa)
A0A1V6RYP8Uncharacterized protein. (823 aa)
A0A1V6RYX3DNA_mis_repair domain-containing protein. (887 aa)
A0A1V6RZ27DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (344 aa)
A0A1V6RZ32ANK_REP_REGION domain-containing protein. (369 aa)
A0A1V6RZR4AAA domain-containing protein. (352 aa)
A0A1V6S023RING-type domain-containing protein. (228 aa)
A0A1V6S0C7Uncharacterized protein. (992 aa)
A0A1V6S0F3Cell division control protein; Belongs to the CDC6/cdc18 family. (643 aa)
A0A1V6S0H83'-5' exonuclease domain-containing protein. (1247 aa)
A0A1V6S0I3Uncharacterized protein. (822 aa)
A0A1V6S0V8Uncharacterized protein. (874 aa)
A0A1V6S0Y2Uncharacterized protein. (317 aa)
A0A1V6S128RECA_2 domain-containing protein. (529 aa)
A0A1V6S1R3DBF4-type domain-containing protein. (648 aa)
A0A1V6S2J1Uncharacterized protein. (383 aa)
A0A1V6S2N9DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (620 aa)
A0A1V6S318Protein kinase domain-containing protein. (763 aa)
A0A1V6S3F4RECA_2 domain-containing protein. (395 aa)
A0A1V6S4F4MutL_C domain-containing protein. (971 aa)
A0A1V6S4H2Uncharacterized protein. (964 aa)
A0A1V6S4M2Uncharacterized protein. (77 aa)
A0A1V6S4S6Sld5 domain-containing protein. (178 aa)
A0A1V6S5C6AAA_23 domain-containing protein. (1297 aa)
A0A1V6S5K3DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (271 aa)
A0A1V6S5N5DNA polymerase. (1700 aa)
A0A1V6S5Q0DUF1767 domain-containing protein. (243 aa)
A0A1V6S5W2AAA domain-containing protein. (719 aa)
A0A1V6S6D5DNA primase; Belongs to the eukaryotic-type primase small subunit family. (503 aa)
A0A1V6S6G7AAA domain-containing protein. (393 aa)
A0A1V6S6K3Uncharacterized protein. (734 aa)
A0A1V6S6X9Uncharacterized protein. (851 aa)
A0A1V6S736zf-GRF domain-containing protein. (339 aa)
A0A1V6S795Sld5 domain-containing protein. (229 aa)
A0A1V6S7D3Zn(2)-C6 fungal-type domain-containing protein. (388 aa)
A0A1V6S7T2UmuC domain-containing protein. (573 aa)
A0A1V6S819DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1129 aa)
A0A1V6S8C0Uncharacterized protein. (197 aa)
A0A1V6S8V5ERCC4 domain-containing protein. (652 aa)
A0A1V6S8X9DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (656 aa)
A0A1V6S994DNA_mis_repair domain-containing protein. (752 aa)
A0A1V6S9K8Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2894 aa)
A0A1V6SA09DNA_MISMATCH_REPAIR_2 domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR). (943 aa)
A0A1V6SAH1ERCC4 domain-containing protein. (589 aa)
A0A1V6SBH6DNA helicase; Belongs to the MCM family. (877 aa)
A0A1V6SBK3DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2227 aa)
A0A1V6SBX2Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (2474 aa)
A0A1V6SCE3Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (867 aa)
A0A1V6SCG3Uncharacterized protein. (539 aa)
A0A1V6SCK9DNA helicase; Belongs to the MCM family. (1001 aa)
A0A1V6SD43Uncharacterized protein. (1172 aa)
A0A1V6SDH8Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (268 aa)
A0A1V6SDV2Uncharacterized protein. (145 aa)
A0A1V6SE62BRCT domain-containing protein. (1425 aa)
A0A1V6SEL8AAA domain-containing protein. (1069 aa)
A0A1V6SEP6Uncharacterized protein. (556 aa)
A0A1V6SG70Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (763 aa)
Your Current Organism:
Penicillium vulpinum
NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme
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