(12 nodes) Activation of protein kinase activity network (Penicillium vulpinum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6RZM2	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (114 aa)
	A0A1V6SCH6	RING-type domain-containing protein. (370 aa)
	A0A1V6S394	Uncharacterized protein; Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa)
	A0A1V6S1R3	DBF4-type domain-containing protein. (648 aa)
	A0A1V6RYB4	Uncharacterized protein. (307 aa)
	A0A1V6RW10	Uncharacterized protein. (383 aa)
	A0A1V6RTH6	Uncharacterized protein. (454 aa)
	A0A1V6RS92	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (444 aa)
	A0A1V6RG21	Uncharacterized protein. (280 aa)
	A0A1V6RFE1	Uncharacterized protein. (731 aa)
	A0A1V6RF01	Uncharacterized protein. (286 aa)
	A0A1V6R2S0	Uncharacterized protein. (363 aa)

Your Current Organism:

Penicillium vulpinum

NCBI taxonomy Id: 29845
Other names: P. vulpinum, Penicillium claviforme

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6R2S0	A0A1V6SCH6	Uncharacterized protein.	RING-type domain-containing protein.	0.677
A0A1V6RF01	A0A1V6RG21	Uncharacterized protein.	Uncharacterized protein.	0.491
A0A1V6RFE1	A0A1V6SCH6	Uncharacterized protein.	RING-type domain-containing protein.	0.677
A0A1V6RG21	A0A1V6RF01	Uncharacterized protein.	Uncharacterized protein.	0.491
A0A1V6RG21	A0A1V6RW10	Uncharacterized protein.	Uncharacterized protein.	0.466
A0A1V6RG21	A0A1V6RYB4	Uncharacterized protein.	Uncharacterized protein.	0.660
A0A1V6RW10	A0A1V6RG21	Uncharacterized protein.	Uncharacterized protein.	0.466
A0A1V6RW10	A0A1V6RYB4	Uncharacterized protein.	Uncharacterized protein.	0.466
A0A1V6RYB4	A0A1V6RG21	Uncharacterized protein.	Uncharacterized protein.	0.660
A0A1V6RYB4	A0A1V6RW10	Uncharacterized protein.	Uncharacterized protein.	0.466
A0A1V6SCH6	A0A1V6R2S0	RING-type domain-containing protein.	Uncharacterized protein.	0.677
A0A1V6SCH6	A0A1V6RFE1	RING-type domain-containing protein.	Uncharacterized protein.	0.677