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| | ahcY | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (478 aa) |
| | ABW09600.1 | TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: fal:FRAAL6756 aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex. (216 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (87 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (769 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (239 aa) |
| | purC | KEGG: fal:FRAAL6667 phosphoribosylaminoimidazole-succinocarboxamide synthase (SAICAR synthetase); TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (354 aa) |
| | ABW09673.1 | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: fal:FRAAL6665 adenylosuccinate lyase (adenylosuccinase) (ASL); Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (435 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (187 aa) |
| | purD | Phosphoribosylamine--glycine ligase; KEGG: fal:FRAAL6663 phosphoribosylglycinamide synthetase (GAR synthetase); TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; Belongs to the GARS family. (439 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (427 aa) |
| | psuG | Indigoidine synthase A family protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (306 aa) |
| | ABW09760.1 | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: fal:FRAAL6591 phosphoribosyl-ATP pyrophosphatase (PRA-PH); Belongs to the PRA-PH family. (149 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (282 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (709 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (437 aa) |
| | ABW10069.1 | PFAM: Survival protein SurE; KEGG: mem:Memar_1385 stationary-phase survival protein SurE. (271 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (1080 aa) |
| | ABW10122.1 | PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: fal:FRAAL6420 putative diaminopimelate decarboxylase protein. (453 aa) |
| | ABW10146.1 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: fal:FRAAL6398 putative ligase (partial match); Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (193 aa) |
| | ABW10263.1 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: fal:FRAAL6235 putative transcriptional regulator (partial match). (436 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (218 aa) |
| | ABW10328.1 | PFAM: aminotransferase class I and II; KEGG: fal:FRAAL6125 N-succinyl-L,L-diaminopimelate aminotransferase. (618 aa) |
| | ABW10329.1 | KEGG: fal:FRAAL6124 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (293 aa) |
| | ABW10330.1 | TIGRFAM: succinyl-diaminopimelate desuccinylase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: fal:FRAAL6123 succinyl-diaminopimelate desuccinylase (SDAP). (376 aa) |
| | ABW10359.1 | KEGG: fal:FRAAL6068 hypothetical protein; putative chorismate mutase. (119 aa) |
| | ABW10366.1 | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: fal:FRAAL6066 putative transaminase. (421 aa) |
| | ABW10411.1 | TIGRFAM: histidinol-phosphate phosphatase, putative; PFAM: inositol monophosphatase; KEGG: fal:FRAAL6017 putative inositol monophosphatase; putative signal peptide. (280 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (355 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (459 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (375 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (247 aa) |
| | thyX | Thymidylate synthase, flavin-dependent; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (274 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (321 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (307 aa) |
| | ABW10689.1 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (1011 aa) |
| | ABW10912.1 | KEGG: fal:FRAAL3686 putative methylenetetrahydrofolate reductase. (91 aa) |
| | ABW11033.1 | PFAM: prephenate dehydratase; KEGG: fal:FRAAL3225 prephenate dehydratase (PDT). (317 aa) |
| | ABW11081.1 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1262 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | ABW11101.1 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: fal:FRAAL0918 aminoquinate/shkimate dehydrogenase. (291 aa) |
| | ABW11102.1 | PFAM: 3-dehydroquinate synthase; KEGG: fal:FRAAL0919 dehydroquinate synthase. (364 aa) |
| | ABW11135.1 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: fal:FRAAL5249 shikimate 5-dehydrogenase. (298 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (394 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (187 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (371 aa) |
| | pyrR | Uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. (197 aa) |
| | pyrB | KEGG: fal:FRAAL5238 aspartate carbamoyltransferase (aspartate transcarbamylase) (ATCase); TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (309 aa) |
| | pyrC | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (451 aa) |
| | ABW11146.1 | KEGG: fal:FRAAL5236 hypothetical protein; putative signal peptide. (591 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: fal:FRAAL5235 carbamoyl phosphate synthetase, pyrimidin-specific small subunit; Belongs to the CarA family. (397 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: fal:FRAAL5234 carbamoyl phosphate synthase, pyrimidin specific large subunit; Belongs to the CarB family. (1136 aa) |
| | pyrF | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (279 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (192 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (398 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (360 aa) |
| | argJ | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (390 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (344 aa) |
| | argD | TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL5205 acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (414 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. (317 aa) |
| | argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (189 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: fal:FRAAL5202 argininosuccinate synthase (citrulline--aspartate ligase); Belongs to the argininosuccinate synthase family. Type 1 subfamily. (400 aa) |
| | argH | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: fal:FRAAL5201 argininosuccinate lyase. (511 aa) |
| | ABW11183.1 | TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); KEGG: fal:FRAAL5200 3-methyladenine DNA glycosylase; Belongs to the DNA glycosylase MPG family. (224 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa) |
| | ABW11236.1 | Adenosine kinase; PFAM: PfkB domain protein; KEGG: fal:FRAAL5126 adenosine kinase. (326 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (432 aa) |
| | ABW11271.1 | KEGG: fal:FRAAL5083 phospho-2-dehydro-3-deoxyheptonate aldolase (phospho-2-keto-3-deoxyheptonate aldolase) (DAHP synthetase) (3-deoxy-D-arabino-heptulosonate 7-phosphate synthase); TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase class II. (452 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (431 aa) |
| | hisC | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: fal:FRAAL5003 histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (453 aa) |
| | hisB | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: fal:FRAAL5002 imidazoleglycerol-phosphate dehydratase. (195 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (204 aa) |
| | hisA | Bifunctional HisA/TrpF protein; KEGG: fal:FRAAL4977 N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-i midazolecarboxamide isomerase, N-(5'-phosphoribosyl)anthranilate isomerase; TIGRFAM: bifunctional HisA/TrpF protein; PFAM: histidine biosynthesis protein. (245 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (248 aa) |
| | hisI | Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (169 aa) |
| | trpE | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (525 aa) |
| | trpC | PFAM: Indole-3-glycerol phosphate synthase; KEGG: fal:FRAAL4969 indole-3-glycerol phosphate synthase 1 (IGPS 1); Belongs to the TrpC family. (268 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (490 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (306 aa) |
| | adk-2 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (199 aa) |
| | ABW11425.1 | PFAM: prephenate dehydratase; KEGG: fal:FRAAL4901 prephenate dehydratase. (287 aa) |
| | ABW11830.1 | PFAM: glutamine amidotransferase class-I; KEGG: rxy:Rxyl_1030 glutamine amidotransferase class-I. (257 aa) |
| | ABW11860.1 | PFAM: Proline dehydrogenase; KEGG: fal:FRAAL4348 putative proline dehydrogenase (proline dehydrogenase family protein). (360 aa) |
| | glyA-2 | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa) |
| | ABW12032.1 | TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family protein; KEGG: tbr:Tb10.6k15.0290 hypothetical protein. (194 aa) |
| | ABW12244.1 | PFAM: S-adenosyl-L-homocysteine hydrolase; tetrahydrofolate dehydrogenase/cyclohydrolase; KEGG: asa:ASA_2744 S-adenosyl-L-homocysteine hydrolase. (377 aa) |
| | tmk-2 | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (224 aa) |
| | ABW12250.1 | PFAM: aminoglycoside phosphotransferase; KEGG: bja:blr5425 hypothetical protein. (312 aa) |
| | dapB-2 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (248 aa) |
| | ABW12901.1 | KEGG: sma:SAV2046 putative methionine synthase. (54 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (766 aa) |
| | ABW13018.1 | PFAM: glutamine amidotransferase class-I; Anthranilate synthase component I and chorismate binding protein; KEGG: pau:PA14_09440 phenazine biosynthesis protein PhzE. (685 aa) |
| | ABW13270.1 | PFAM: glutamine amidotransferase class-I; Anthranilate synthase component I and chorismate binding protein; KEGG: stp:Strop_2960 glutamine amidotransferase class-I. (657 aa) |
| | ABW13492.1 | Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: fal:FRAAL4801 putative LysR family transcriptional regulator. (312 aa) |
| | ABW13493.1 | PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: ppu:PP_3225 D-isomer specific 2-hydroxyacid dehydrogenase family protein. (343 aa) |
| | ABW13515.1 | KEGG: fal:FRAAL3674 putative kinase. (230 aa) |
| | ABW13566.1 | PFAM: Formiminotransferase-cyclodeaminase; KEGG: rha:RHA1_ro01816 probable methenyltetrahydrofolate cyclohydrolase. (268 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (275 aa) |
| | metXA | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (414 aa) |
| | ABW13639.1 | KEGG: fal:FRAAL4362 O-acetylhomoserine (thiol)-lyase (O-acetylhomoserine sulfhydrylase) (OAH sulfhydrylase) (homocysteine synthase); TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (431 aa) |
| | ABW13641.1 | KEGG: fal:FRAAL4842 O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (468 aa) |
| | argJ-2 | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (408 aa) |
| | ABW14334.1 | Uridine kinase-like protein; KEGG: fal:FRAAL3674 putative kinase. (268 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa) |
| | ABW14420.1 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: fal:FRAAL2252 putative prephenate dehydrogenase. (396 aa) |
| | ABW14484.1 | KEGG: fal:FRAAL2163 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (291 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa) |
| | ABW14517.1 | PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: fal:FRAAL2126 anthranilate synthase. (398 aa) |
| | dut | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (231 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (371 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa) |
| | ABW14640.1 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate. (321 aa) |
| | ABW14735.1 | PFAM: selenium-binding protein; KEGG: sen:SACE_3282 56kDa selenium binding. (574 aa) |
| | ABW14847.1 | Hypothetical protein. (341 aa) |
| | ABW14848.1 | Thymidylate kinase-like protein; KEGG: xcb:XC_4020 thymidylate kinase. (226 aa) |
| | ABW15230.1 | KEGG: fal:FRAAL1247 putative acetyltransferase. (224 aa) |
| | ABW15266.1 | TIGRFAM: uracil phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: fal:FRAAL1198 uracil phosphoribosyltransferase (UMP pyrophosphorylase) (UPRTase); Belongs to the UPRTase family. (207 aa) |
| | ABW15269.1 | Purine nucleotide phosphorylase; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; purine nucleotide phosphorylase; PFAM: purine phosphorylase family 2; KEGG: fal:FRAAL1200 purine nucleoside phosphorylase (inosine phosphorylase) (PNP). (348 aa) |
| | add | KEGG: fal:FRAAL1195 adenosine deaminase 5 (adenosine aminohydrolase 5); TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (364 aa) |
| | ABW15278.1 | KEGG: fal:FRAAL1194 thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain. (444 aa) |
| | ABW15279.1 | TIGRFAM: cytidine deaminase; PFAM: CMP/dCMP deaminase zinc-binding; KEGG: fal:FRAAL1193 cytidine deaminase. (199 aa) |
| | purN | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate; Belongs to the GART family. (828 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (534 aa) |
| | ABW15341.1 | TIGRFAM: IMP dehydrogenase family protein; KEGG: fal:FRAAL1140 putative inosine-5'-monophosphate dehydrogenase. (376 aa) |
| | guaB | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (597 aa) |
| | adk-3 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (217 aa) |
| | ABW15408.1 | Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: fal:FRAAL1062 aspartate aminotransferase (transaminase A) (ASPAT). (402 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (175 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (297 aa) |
| | ABW15631.1 | PFAM: protein of unknown function DUF201; KEGG: ace:Acel_0637 protein of unknown function DUF201. (325 aa) |
| | ABW15670.1 | PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2797 aminotransferase, class I and II. (397 aa) |
| | ABW15712.1 | PFAM: methylenetetrahydrofolate reductase; KEGG: fal:FRAAL3686 putative methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (257 aa) |
| | ABW15761.1 | TIGRFAM: cystathionine beta-synthase; PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: fal:FRAAL0784 cysteine synthase B, O-acetylserine sulfhydrylase B. (463 aa) |
| | ABW15762.1 | Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0783 cystathionine gamma-synthase, PLP-dependent. (385 aa) |
| | tmk-3 | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (241 aa) |
| | ABW15910.1 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: fal:FRAAL0605 aspartokinase (aspartate kinase) [contains: aspartokinase alpha subunit (ASK-alpha); aspartokinase beta subunit (ASK-beta)]; Belongs to the aspartokinase family. (422 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (353 aa) |
| | ABW16314.1 | KEGG: sen:SACE_6492 inositol-phosphate phosphatase. (175 aa) |
| | aroE | Shikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (290 aa) |
| | ABW16388.1 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: stm:STM3859 shikimate 5-dehydrogenase. (272 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: fal:FRAAL0129 phosphoribosylaminoimidazole synthetase (AIR synthetase); TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (386 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (623 aa) |
