STRINGSTRING
ABW15670.1 ABW15670.1 gcvP gcvP ABW10120.1 ABW10120.1 ABW10121.1 ABW10121.1 ABW10328.1 ABW10328.1 ABW10353.1 ABW10353.1 ABW10366.1 ABW10366.1 ABW10405.1 ABW10405.1 ABW10425.1 ABW10425.1 ABW10449.1 ABW10449.1 glyA glyA ABW10535.1 ABW10535.1 ABW11001.1 ABW11001.1 ABW11097.1 ABW11097.1 ABW11108.1 ABW11108.1 argD argD ABW11238.1 ABW11238.1 hisC hisC ABW11526.1 ABW11526.1 ABW11653.1 ABW11653.1 ABW11805.1 ABW11805.1 ABW11809.1 ABW11809.1 glyA-2 glyA-2 ABW13463.1 ABW13463.1 bioA bioA ABW13639.1 ABW13639.1 ABW13641.1 ABW13641.1 ABW14207.1 ABW14207.1 ABW14287.1 ABW14287.1 ABW15072.1 ABW15072.1 ABW15111.1 ABW15111.1 ABW15408.1 ABW15408.1 hemL hemL ABW15632.1 ABW15632.1 ABW15762.1 ABW15762.1 ABW15872.1 ABW15872.1 ABW15994.1 ABW15994.1 ABW16044.1 ABW16044.1 ABW16202.1 ABW16202.1 serC serC ABW16578.1 ABW16578.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABW15670.1PFAM: aminotransferase class I and II; KEGG: dvl:Dvul_2797 aminotransferase, class I and II. (397 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (1080 aa)
ABW10120.1PFAM: Pyridoxal-dependent decarboxylase; KEGG: fal:FRAAL6422 putative L-2,4-diaminobutyrate decarboxylase. (484 aa)
ABW10121.1TIGRFAM: 2,4-diaminobutyrate 4-transaminase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL6421 putative diaminobutyrate--2-oxoglutarate aminotransferase (L-diaminobutyric acid transaminase) (diaminobutyrate transaminase) (DABA aminotransferase) (DABA-AT) (L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
ABW10328.1PFAM: aminotransferase class I and II; KEGG: fal:FRAAL6125 N-succinyl-L,L-diaminopimelate aminotransferase. (618 aa)
ABW10353.1TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL6081 4-aminobutyrate aminotransferase, PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (489 aa)
ABW10366.1Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: fal:FRAAL6066 putative transaminase. (421 aa)
ABW10405.1PFAM: aminotransferase class-III; KEGG: fal:FRAAL6024 putative glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (473 aa)
ABW10425.18-amino-7-oxononanoate synthase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: fal:FRAAL6001 8-amino-7-oxononanoate synthase. (418 aa)
ABW10449.1PFAM: aminotransferase class V; aminotransferase class I and II; KEGG: fal:FRAAL5974 hypothetical protein; putative membrane protein; putative glycine C-acetyltransferase. (492 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
ABW10535.1PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL5862 cysteine desulfurase. (419 aa)
ABW11001.1PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: spu:759109 similar to DegT/DnrJ/EryC1/StrS aminotransferase family protein; Belongs to the DegT/DnrJ/EryC1 family. (408 aa)
ABW11097.1Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0914 3-amino-5-hydroxybenzoic acid synthase; Belongs to the DegT/DnrJ/EryC1 family. (388 aa)
ABW11108.1Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: fal:FRAAL4323 putative aminotransferase. (395 aa)
argDTIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL5205 acetylornithine transaminase (NAcOATase and DapATase), PLP-dependent; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (414 aa)
ABW11238.1PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL5124 cysteine desulfurase (tRNA sulfurtransferase), PLP-dependent. (409 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: fal:FRAAL5003 histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase); Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (453 aa)
ABW11526.1Cysteine desulfurase, SufS subfamily; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (441 aa)
ABW11653.1PFAM: aminotransferase class V; KEGG: fal:FRAAL4529 hypothetical protein; putative aminotransferase domain. (426 aa)
ABW11805.1PFAM: aminotransferase class-III; KEGG: fal:FRAAL4414 L-lysine-epsilon aminotransferase (L-lysine aminotransferase) (lysine 6-aminotransferase); Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (479 aa)
ABW11809.1Pyridoxal-dependent decarboxylase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; Pyridoxal-dependent decarboxylase; KEGG: fal:FRAAL4406 putative amino acid decarboxylase, pyridoxal-dependent protein. (518 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
ABW13463.1Threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0384 L-allo-threonine aldolase, PLP-dependent. (361 aa)
bioAAdenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (428 aa)
ABW13639.1KEGG: fal:FRAAL4362 O-acetylhomoserine (thiol)-lyase (O-acetylhomoserine sulfhydrylase) (OAH sulfhydrylase) (homocysteine synthase); TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (431 aa)
ABW13641.1KEGG: fal:FRAAL4842 O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein. (468 aa)
ABW14207.1Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0914 3-amino-5-hydroxybenzoic acid synthase; Belongs to the DegT/DnrJ/EryC1 family. (392 aa)
ABW14287.1Cysteine desulfurase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL4247 putative selenocysteine lyase. (518 aa)
ABW15072.1PFAM: aminotransferase class-III; KEGG: fal:FRAAL1423 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (446 aa)
ABW15111.1PFAM: aminotransferase class-III; KEGG: sma:SAV2285 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (438 aa)
ABW15408.1Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: fal:FRAAL1062 aspartate aminotransferase (transaminase A) (ASPAT). (402 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: fal:FRAAL0997 glutamate-1-semialdehyde aminotransferase (aminomutase), PLP-dependent. (449 aa)
ABW15632.1PFAM: aminotransferase class V; DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: dde:Dde_3697 aminotransferase, DegT/DnrJ/EryC1/StrS family; Belongs to the DegT/DnrJ/EryC1 family. (383 aa)
ABW15762.1Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0783 cystathionine gamma-synthase, PLP-dependent. (385 aa)
ABW15872.1PFAM: Pyridoxal-dependent decarboxylase; KEGG: fal:FRAAL0631 putative pyridoxal-dependent decarboxylase. (474 aa)
ABW15994.1Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: fal:FRAAL0507 putative aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (378 aa)
ABW16044.1Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: fal:FRAAL3075 hypothetical protein. (416 aa)
ABW16202.1PFAM: aminotransferase class V; KEGG: fal:FRAAL6800 cysteine desulfurase (nitrogenase metalloclusters biosynthesis protein NifS). (406 aa)
serCPutative phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (374 aa)
ABW16578.1PFAM: aminotransferase class I and II; KEGG: fal:FRAAL0078 putative aspartate aminotransferase. (404 aa)
Your Current Organism:
Frankia sp. EAN1pec
NCBI taxonomy Id: 298653
Other names: F. sp. EAN1pec
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