STRINGSTRING
ABW09644.1 ABW09644.1 gcvP gcvP ABW10116.1 ABW10116.1 glyA glyA ABW10490.1 ABW10490.1 ABW10500.1 ABW10500.1 ABW10524.1 ABW10524.1 ABW10715.1 ABW10715.1 ABW11204.1 ABW11204.1 ABW11207.1 ABW11207.1 ABW11208.1 ABW11208.1 ABW11218.1 ABW11218.1 gcvT gcvT ABW11380.1 ABW11380.1 ABW11381.1 ABW11381.1 ABW11455.1 ABW11455.1 ABW11603.1 ABW11603.1 ABW11939.1 ABW11939.1 glyA-2 glyA-2 ABW12137.1 ABW12137.1 ABW12152.1 ABW12152.1 ABW12363.1 ABW12363.1 ABW12621.1 ABW12621.1 ABW12642.1 ABW12642.1 ABW12791.1 ABW12791.1 ABW13319.1 ABW13319.1 ABW13435.1 ABW13435.1 ABW13693.1 ABW13693.1 ABW13694.1 ABW13694.1 ABW13950.1 ABW13950.1 gcvH gcvH ABW14830.1 ABW14830.1 ABW15073.1 ABW15073.1 ABW15258.1 ABW15258.1 ABW15260.1 ABW15260.1 mdh mdh ABW15839.1 ABW15839.1 ABW15853.1 ABW15853.1 ABW16125.1 ABW16125.1 glcB glcB ABW16351.1 ABW16351.1 ABW16390.1 ABW16390.1 ABW16546.1 ABW16546.1 ABW16548.1 ABW16548.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABW09644.1PFAM: Haloacid dehalogenase domain protein hydrolase type 3; KEGG: fal:FRAAL6699 hypothetical protein. (266 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (1080 aa)
ABW10116.1Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: fal:FRAAL6426 putative glutamine synthetase. (470 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa)
ABW10490.1methylmalonyl-CoA mutase, large subunit; KEGG: fal:FRAAL5921 coenzyme B12-dependent mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (666 aa)
ABW10500.1KEGG: fal:FRAAL5910 acetyl-CoA acetyltransferase with thiolase domain; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
ABW10524.1TIGRFAM: acetate--CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: fal:FRAAL5886 acetyl-CoA synthetase, has propionyl-CoA synthetase activity. (673 aa)
ABW10715.1Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: fal:FRAAL5672 propionyl-CoA carboxylase beta chain 6 (PCCase) (propanoyl-CoA:carbon dioxide ligase). (489 aa)
ABW11204.1PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fal:FRAAL5165 glutamine synthetase 2 (glutamate--ammonia ligase 2). (452 aa)
ABW11207.1Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fal:FRAAL5163 glutamine synthetase II (glutamate--ammonia ligase II) (GSII). (356 aa)
ABW11208.1TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: fal:FRAAL5161 glutamine synthetase. (474 aa)
ABW11218.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: fal:FRAAL5151 dihydrolipoyl dehydrogenase (E3 component of branched-chain alpha-keto acid dehydrogenase complex) (LPD-Val) (dihydrolipoamide dehydrogenase). (460 aa)
gcvTGlycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (365 aa)
ABW11380.1PFAM: methylmalonyl-CoA mutase; KEGG: fal:FRAAL4951 methylmalonyl-CoA mutase small subunit (MCM-beta). (653 aa)
ABW11381.1methylmalonyl-CoA mutase, large subunit; KEGG: fal:FRAAL4950 methylmalonyl-CoA mutase (MCM); TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (740 aa)
ABW11455.1PFAM: FAD linked oxidase domain protein; KEGG: fal:FRAAL3861 putative glycolate oxidoreductase (partial match). (478 aa)
ABW11603.1TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: fal:FRAAL2064 aconitate hydratase 1. (927 aa)
ABW11939.1PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: fal:FRAAL4275 hypothetical protein. (141 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
ABW12137.1KEGG: fal:FRAAL2618 putative acetyl-CoA acetyltransferase with thiolase domain; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (389 aa)
ABW12152.1KEGG: mva:Mvan_1976 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
ABW12363.1KEGG: rha:RHA1_ro04204 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ABW12621.1Hypothetical protein; KEGG: gme:Gmet_2237 glyoxalase/bleomycin resistance protein/dioxygenase. (172 aa)
ABW12642.1PFAM: AMP-dependent synthetase and ligase; KEGG: nfa:nfa41510 putative acyl-CoA synthetase. (530 aa)
ABW12791.1Propanoyl-CoA C-acyltransferase; PFAM: Thiolase; KEGG: mav:MAV_1596 putative thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (380 aa)
ABW13319.1KEGG: sen:SACE_4011 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (403 aa)
ABW13435.1PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: fal:FRAAL3159 acetyl-/propionyl-coenzyme A carboxylase alpha chain [includes: biotin carboxylase and biotin carboxyl carrier protein (BccP)]. (700 aa)
ABW13693.1PFAM: cobalamin B12-binding domain protein; KEGG: mjl:Mjls_3811 cobalamin B12-binding domain protein. (133 aa)
ABW13694.1KEGG: mkm:Mkms_3900 methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (525 aa)
ABW13950.1KEGG: mjl:Mjls_1750 acetyl-CoA acetyltransferases; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (388 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
ABW14830.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: nfa:nfa52650 putative dihydrolipoamide dehydrogenase. (466 aa)
ABW15073.1PFAM: glycerate kinase; KEGG: fal:FRAAL6785 glycerate kinase I; Belongs to the glycerate kinase type-1 family. (397 aa)
ABW15258.1PFAM: carboxyl transferase; KEGG: fal:FRAAL1212 propionyl-CoA carboxylase beta chain (PCCase) (propanoyl-CoA:carbon dioxide ligase). (551 aa)
ABW15260.1Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: fal:FRAAL1210 biotin carboxylase; biotin carboxyl carrier protein (bifunctional protein). (587 aa)
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (310 aa)
ABW15839.1PFAM: glutamine synthetase catalytic region; KEGG: fal:FRAAL0678 glutamine synthetase (glutamate--ammonia ligase). (496 aa)
ABW15853.1KEGG: fal:FRAAL0660 putative formate dehydrogenase. (225 aa)
ABW16125.1PFAM: Catalase domain protein; KEGG: fal:FRAAL3167 catalase. (507 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
ABW16351.12-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; KEGG: sma:SAV5878 putative 2-keto-3-deoxygluconate 6-phosphate aldolase and 2-keto-4-hydroxyglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase. (223 aa)
ABW16390.1KEGG: rpb:RPB_2052 large subunit of N,N-dimethylformamidase. (757 aa)
ABW16546.1KEGG: fal:FRAAL0111 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (455 aa)
ABW16548.1PFAM: Citrate synthase; KEGG: fal:FRAAL0109 citrate synthase 2; Belongs to the citrate synthase family. (364 aa)
Your Current Organism:
Frankia sp. EAN1pec
NCBI taxonomy Id: 298653
Other names: F. sp. EAN1pec
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