STRINGSTRING
GJD2 GJD2 ADCY9 ADCY9 PRKCB PRKCB GRM5 GRM5 ADCY8 ADCY8 NRAS NRAS HTR2B HTR2B PDGFA PDGFA CSNK1D CSNK1D LOC110470948 LOC110470948 ADCY5 ADCY5 PLCB2 PLCB2 TUBB1 TUBB1 GNAS GNAS LOC110483639 LOC110483639 TUBB3 TUBB3 GJD2_0 GJD2_0 PDGFB PDGFB PDGFC PDGFC SOS1 SOS1 DRD2 DRD2 ITPR2 ITPR2 GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 LOC110478245 LOC110478245 LOC110478247 LOC110478247 HTR2A HTR2A PDGFRA PDGFRA EGFR EGFR SOS2 SOS2 LOC110478356 LOC110478356 ADCY7 ADCY7 RAF1 RAF1 GNAI3 GNAI3 MAPK1 MAPK1 TUBA8 TUBA8 GNA11 GNA11 ADRB1 ADRB1 LPAR1 LPAR1 PDGFRB PDGFRB HTR2C HTR2C PRKG1 PRKG1 MAP2K2 MAP2K2 PRKACB PRKACB MAP2K1 MAP2K1 GNAI2 GNAI2 EGF EGF LOC110469156 LOC110469156 LOC110470681 LOC110470681 MAP3K2 MAP3K2 CDK1 CDK1 TUBB4B TUBB4B TUBB6 TUBB6 GRM1 GRM1 SRC SRC PLCB4 PLCB4 PLCB1 PLCB1 GRB2 GRB2 DRD1 DRD1 PRKCA PRKCA TJP1 TJP1 HRAS HRAS ADCY2 ADCY2 GJA1 GJA1 LOC110469766 LOC110469766 TUBA1C TUBA1C TUBA1B TUBA1B ITPR1 ITPR1 GUCY1A2 GUCY1A2 LOC110477391 LOC110477391
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (304 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1348 aa)
PRKCBNon-specific serine/threonine protein kinase. (641 aa)
GRM5Metabotropic glutamate receptor 5. (1189 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1239 aa)
NRASGTPase NRas. (189 aa)
HTR2B5-hydroxytryptamine receptor 2B. (452 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (237 aa)
CSNK1DCasein kinase I isoform delta; Belongs to the protein kinase superfamily. (415 aa)
LOC110470948Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (516 aa)
ADCY5Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1216 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1191 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha. (414 aa)
LOC110483639Guanylate cyclase soluble subunit beta-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (800 aa)
TUBB3Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
GJD2_0Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (345 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (251 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
SOS1Son of sevenless 1. (1322 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (688 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
LOC110478245Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
LOC110478247Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1096 aa)
EGFRReceptor protein-tyrosine kinase. (1222 aa)
SOS2Son of sevenless 2. (1331 aa)
LOC110478356Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (487 aa)
ADCY7Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (991 aa)
RAF1RAF proto-oncogene serine/threonine-protein kinase. (647 aa)
GNAI3Guanine nucleotide-binding protein G(K) subunit alpha. (354 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (368 aa)
TUBA8Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
GNA11Guanine nucleotide-binding protein subunit alpha-11. (359 aa)
ADRB1Adrenergic receptor beta-1. (436 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1091 aa)
HTR2C5-hydroxytryptamine receptor 2C. (472 aa)
PRKG1cGMP-dependent protein kinase. (686 aa)
MAP2K2Dual specificity mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (402 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta; Belongs to the protein kinase superfamily. (351 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
GNAI2Guanine nucleotide-binding protein G(I) subunit alpha-2. (355 aa)
EGFPro-epidermal growth factor. (1254 aa)
LOC110469156Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
LOC110470681Guanine nucleotide-binding protein G(Q) subunit alpha. (359 aa)
MAP3K2Mitogen-activated protein kinase kinase kinase 2. (624 aa)
CDK1Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
GRM1Metabotropic glutamate receptor 1. (1185 aa)
SRCTyrosine-protein kinase. (545 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1219 aa)
GRB2Growth factor receptor-bound protein 2. (217 aa)
DRD1D(1A) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (453 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
TJP1Tight junction protein ZO-1; Belongs to the MAGUK family. (1877 aa)
HRASGTPase HRas. (189 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1096 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
LOC110469766Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (449 aa)
TUBA1BTubulin alpha-1B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2790 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (716 aa)
LOC110477391Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1142 aa)
Your Current Organism:
Lonchura striata
NCBI taxonomy Id: 299123
Other names: Bengalese finch, L. striata domestica, Lonchura domestica, Lonchura striata domestica, society finch
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