(61 nodes) Regulation of actin filament length network (Leptotrombidium deliense)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	B4U80_08283	Nuclear pore complex protein Nup98/Nup96-like protein. (1497 aa)
	B4U80_14694	Profilin; Belongs to the profilin family. (166 aa)
	B4U80_05740	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (213 aa)
	B4U80_07106	Dynamin-like isoform X10. (207 aa)
	B4U80_14515	Protein kinase domain-containing protein. (145 aa)
	B4U80_07286	Dynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (205 aa)
	B4U80_01735	Dynamin-2-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (129 aa)
	B4U80_01188	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (220 aa)
	B4U80_11936	Profilin; Belongs to the profilin family. (150 aa)
	B4U80_00372	Protein phosphatase Slingshot-like protein. (234 aa)
	B4U80_06422	Dynamin-2-like protein. (167 aa)
	B4U80_06423	Dynamin-1-like isoform X14. (297 aa)
	B4U80_02989	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (640 aa)
	B4U80_02111	Dynamin-1-like protein. (284 aa)
	B4U80_13459	FCH and double SH3 domains protein 2-like protein. (450 aa)
	B4U80_08439	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (582 aa)
	B4U80_05528	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
	B4U80_04950	Casein kinase I isoform delta-A-like protein; Belongs to the protein kinase superfamily. (399 aa)
	B4U80_08567	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (310 aa)
	B4U80_00099	Src substrate cortactin-like protein. (635 aa)
	B4U80_04749	Ataxin-2-like protein isoform X2. (510 aa)
	B4U80_06492	Cytoplasmic FMR1-interacting protein-like protein. (689 aa)
	B4U80_02623	Villin-1-like protein. (776 aa)
	B4U80_09502	Beta-thymosin 3-like protein. (90 aa)
	B4U80_09158	Leucine-rich repeat-containing protein 16A-like protein. (1170 aa)
	B4U80_09809	Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (183 aa)
	B4U80_07224	Uncharacterized protein. (78 aa)
	B4U80_03648	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (183 aa)
	B4U80_13039	Drf_FH3 domain-containing protein. (680 aa)
	B4U80_06854	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (736 aa)
	B4U80_11192	Drebrin-like protein B. (492 aa)
	B4U80_03080	Tyrosine-protein kinase. (611 aa)
	B4U80_09594	Protein FAM49B-like protein. (325 aa)
	B4U80_01102	Uncharacterized protein. (1262 aa)
	B4U80_01922	Lamin Dm0-like protein; Belongs to the intermediate filament family. (541 aa)
	B4U80_07709	A-kinase anchor protein 1-like protein. (536 aa)
	B4U80_04463	Uncharacterized protein. (686 aa)
	B4U80_08478	Guanine nucleotide-binding protein subunit beta-2-like 1. (324 aa)
	B4U80_01543	Myosin-IIIb-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1165 aa)
	B4U80_00632	Rho GTPase-activating protein 44-like protein. (740 aa)
	B4U80_04002	Formin-binding protein 1-like protein. (621 aa)
	B4U80_00559	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (302 aa)
	B4U80_08193	Dynamin-like protein. (408 aa)
	B4U80_08260	F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (291 aa)
	B4U80_08572	Protein diaphanous-like protein. (1041 aa)
	B4U80_11624	Tropomodulin-like protein. (391 aa)
	B4U80_12731	Uncharacterized protein. (334 aa)
	B4U80_02196	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (278 aa)
	B4U80_09384	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (683 aa)
	B4U80_09894	Twinfilin-2-like isoform X3. (354 aa)
	B4U80_05801	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (191 aa)
	B4U80_09607	Protein phosphatase Slingshot-like protein. (138 aa)
	B4U80_00495	Actin-related protein 2/3 complex subunit 1A-like protein. (1950 aa)
	B4U80_06352	Myotrophin-like protein. (117 aa)
	B4U80_11059	Uncharacterized protein. (445 aa)
	B4U80_09780	Tyrosine-protein kinase. (524 aa)
	B4U80_04310	Actin-interacting protein 1-like protein. (599 aa)
	B4U80_03095	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (840 aa)
	B4U80_10322	LIM zinc-binding domain-containing protein. (617 aa)
	B4U80_04611	Uncharacterized protein. (223 aa)
	B4U80_10332	SH3 domain containing protein 5-like protein. (131 aa)

Your Current Organism:

Leptotrombidium deliense

NCBI taxonomy Id: 299467
Other names: L. deliense, scrub typhus mite

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B4U80_00099	B4U80_00495	A0A443S7V7	A0A443SRP6	Src substrate cortactin-like protein.	Actin-related protein 2/3 complex subunit 1A-like protein.	0.656
B4U80_00099	B4U80_00559	A0A443S7V7	A0A443SLP8	Src substrate cortactin-like protein.	Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.	0.807
B4U80_00099	B4U80_01188	A0A443S7V7	A0A443S0A1	Src substrate cortactin-like protein.	Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_01543	A0A443S7V7	A0A443SK80	Src substrate cortactin-like protein.	Myosin-IIIb-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.460
B4U80_00099	B4U80_01735	A0A443S7V7	A0A443RY69	Src substrate cortactin-like protein.	Dynamin-2-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_01922	A0A443S7V7	A0A443SG13	Src substrate cortactin-like protein.	Lamin Dm0-like protein; Belongs to the intermediate filament family.	0.526
B4U80_00099	B4U80_02111	A0A443S7V7	A0A443S5R5	Src substrate cortactin-like protein.	Dynamin-1-like protein.	0.556
B4U80_00099	B4U80_02196	A0A443S7V7	A0A443SPK1	Src substrate cortactin-like protein.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.668
B4U80_00099	B4U80_02989	A0A443S7V7	A0A443S4K5	Src substrate cortactin-like protein.	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_03080	A0A443S7V7	A0A443SEV3	Src substrate cortactin-like protein.	Tyrosine-protein kinase.	0.492
B4U80_00099	B4U80_03095	A0A443S7V7	A0A443STJ6	Src substrate cortactin-like protein.	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_03648	A0A443S7V7	A0A443SDD9	Src substrate cortactin-like protein.	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_05528	A0A443S7V7	A0A443S687	Src substrate cortactin-like protein.	Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.	0.619
B4U80_00099	B4U80_05740	A0A443S7V7	A0A443RTQ9	Src substrate cortactin-like protein.	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_05801	A0A443S7V7	A0A443SQQ2	Src substrate cortactin-like protein.	Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.	0.722
B4U80_00099	B4U80_06422	A0A443S7V7	A0A443S493	Src substrate cortactin-like protein.	Dynamin-2-like protein.	0.556
B4U80_00099	B4U80_06423	A0A443S7V7	A0A443S4A0	Src substrate cortactin-like protein.	Dynamin-1-like isoform X14.	0.556
B4U80_00099	B4U80_06854	A0A443S7V7	A0A443SEA3	Src substrate cortactin-like protein.	Dynamin-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556
B4U80_00099	B4U80_07106	A0A443S7V7	A0A443RTS7	Src substrate cortactin-like protein.	Dynamin-like isoform X10.	0.556
B4U80_00099	B4U80_07286	A0A443S7V7	A0A443RVJ9	Src substrate cortactin-like protein.	Dynamin-1-like protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.556