STRINGSTRING
Dbus_chr3Lg506 Dbus_chr3Lg506 Dbus_chr2Lg513 Dbus_chr2Lg513 A0A0M4E194 A0A0M4E194 A0A0M3QV98 A0A0M3QV98 A0A0M3QV90 A0A0M3QV90 Dbus_chr3Lg989 Dbus_chr3Lg989 A0A0M4E338 A0A0M4E338 A0A0M5J4V0 A0A0M5J4V0 Dbus_chr2Lg779 Dbus_chr2Lg779 A0A0M5IZZ6 A0A0M5IZZ6 Dbus_chr3Rg682 Dbus_chr3Rg682 A0A0M4F162 A0A0M4F162 A0A0M4EWK0 A0A0M4EWK0 Dbus_chr2Rg766 Dbus_chr2Rg766 Dbus_chrXg241 Dbus_chrXg241 A0A0M4EPR5 A0A0M4EPR5 A0A0M4EP29 A0A0M4EP29 A0A0M4EMJ5 A0A0M4EMJ5 Dbus_chr3Lg146 Dbus_chr3Lg146 A0A0M4ELD7 A0A0M4ELD7 Dbus_chr3Lg688 Dbus_chr3Lg688 A0A0M4EJY6 A0A0M4EJY6 A0A0M4EIZ6 A0A0M4EIZ6 A0A0M4EEW6 A0A0M4EEW6 A0A0M4EA75 A0A0M4EA75 Dbus_chr3Lg507 Dbus_chr3Lg507 Dbus_chr3Lg244 Dbus_chr3Lg244
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Dbus_chr3Lg506Alpha-Spec. (2123 aa)
Dbus_chr2Lg513CG11926. (541 aa)
A0A0M4E194Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (737 aa)
A0A0M3QV98Vps20. (217 aa)
A0A0M3QV90Vps25. (174 aa)
Dbus_chr3Lg989CG5498. (445 aa)
A0A0M4E338Rab5. (536 aa)
A0A0M5J4V0Shrb. (229 aa)
Dbus_chr2Lg779Stam. (690 aa)
A0A0M5IZZ6Vps2. (248 aa)
Dbus_chr3Rg682Rab7. (295 aa)
A0A0M4F162Mop. (1453 aa)
A0A0M4EWK0Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (210 aa)
Dbus_chr2Rg766CG14767. (426 aa)
Dbus_chrXg241CG7192. (359 aa)
A0A0M4EPR5Chmp1. (203 aa)
A0A0M4EP29Vps24. (227 aa)
A0A0M4EMJ5Annexin. (324 aa)
Dbus_chr3Lg146CG6259. (226 aa)
A0A0M4ELD7Vps36. (399 aa)
Dbus_chr3Lg688CG15012. (152 aa)
A0A0M4EJY6CG7967. (315 aa)
A0A0M4EIZ6CG14980. (470 aa)
A0A0M4EEW6CG10103. (412 aa)
A0A0M4EA75CG30423. (112 aa)
Dbus_chr3Lg507Kst. (4354 aa)
Dbus_chr3Lg244CHMP2B. (212 aa)
Your Current Organism:
Drosophila busckii
NCBI taxonomy Id: 30019
Other names: D. busckii
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