55 items (Drosophila busckii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A0M3QY77	CG9356. (444 aa)
	A0A0M3QYL9	CG8202. (941 aa)
	Dbus_chrXg29	Dor. (1156 aa)
	A0A0M4E194	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (737 aa)
	A0A0M4E607	Wash. (502 aa)
	A0A0M4E6Y4	CG18659. (901 aa)
	Dbus_chr2Rg875	Rho1. (205 aa)
	A0A0M4E9R0	Rab2. (215 aa)
	A0A0M4EAS3	Sec71. (1675 aa)
	Dbus_chr2Rg744	Rho1. (193 aa)
	Dbus_chr3Rg216	Past1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (567 aa)
	A0A0M4EDX3	Nuf. (536 aa)
	A0A0M4EG86	Fidipidine. (586 aa)
	Dbus_chrXg734	Grip. (1014 aa)
	Dbus_chrXg1047	CG7039. (200 aa)
	Dbus_chrXg1572	MICAL-like. (802 aa)
	Dbus_chr3Rg390	Protein SYS1 homolog; Involved in protein trafficking. Belongs to the SYS1 family. (160 aa)
	A0A0M4EKU1	CG15087. (732 aa)
	A0A0M4EM34	Rab8. (207 aa)
	Dbus_chr3Rg514	Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (759 aa)
	Dbus_chr3Rg726	Sec10. (710 aa)
	Dbus_chrXg1590	Tomosyn. (1527 aa)
	Dbus_chr3Rg142	UbcD6; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	A0A0M4ES76	L-2-s5379. (296 aa)
	Dbus_chr3Rg180	CG5447. (143 aa)
	A0A0M4EUN9	Sec6. (738 aa)
	Dbus_chrXg1691	UbcD6; Belongs to the ubiquitin-conjugating enzyme family. (177 aa)
	A0A0M4F162	Mop. (1453 aa)
	A0A0M4F1T7	Sec3. (916 aa)
	Dbus_chr3Rg512	Rab11. (172 aa)
	Dbus_chr3Rg920	Snx3. (167 aa)
	A0A0M4F4N1	Exo84. (677 aa)
	Dbus_chrXg318	Rab35. (202 aa)
	Dbus_chrXg151	Gga. (632 aa)
	Dbus_chrXg1376	Vps26. (544 aa)
	Dbus_chr2Lg979	Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (897 aa)
	A0A0M5IXQ2	CG4996. (1173 aa)
	A0A0M5IXZ8	Vps35. (819 aa)
	A0A0M5IYU2	CG7371. (658 aa)
	A0A0M5IYW9	Ik2. (739 aa)
	Dbus_chr2Lg859	Mtm. (622 aa)
	A0A0M5J293	Sec8. (989 aa)
	Dbus_chr3Lg884	Vha16-4; Belongs to the V-ATPase proteolipid subunit family. (662 aa)
	A0A0M5J3Z8	Scat. (951 aa)
	A0A0M5J5U2	CG7083. (430 aa)
	Dbus_chrXg1424	Mer. (637 aa)
	A0A0M5J8G9	CG7197; Belongs to the small GTPase superfamily. Arf family. (180 aa)
	Dbus_chrXg1712	Comt. (744 aa)
	Dbus_chr2Lg118	CG7371. (658 aa)
	Dbus_chr2Lg608	Ex. (1366 aa)
	Dbus_chr2Lg828	CG3338. (907 aa)
	A0A0M3QWG4	Vps26. (477 aa)
	Dbus_chr3Rg893	Scrib. (3235 aa)
	A0A0M3QY10	Comt. (745 aa)
	A0A0M3QY50	Sbf. (1988 aa)

Your Current Organism:

Drosophila busckii

NCBI taxonomy Id: 30019
Other names: D. busckii

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A0M3QWG4	A0A0M5IXZ8	A0A0M3QWG4	A0A0M5IXZ8	Vps26.	Vps35.	0.988
A0A0M3QWG4	Dbus_chr3Lg884	A0A0M3QWG4	A0A0M5J3N4	Vps26.	Vha16-4; Belongs to the V-ATPase proteolipid subunit family.	0.691
A0A0M3QWG4	Dbus_chr3Rg920	A0A0M3QWG4	A0A0M4F4A9	Vps26.	Snx3.	0.968
A0A0M3QY10	A0A0M5J3Z8	A0A0M3QY10	A0A0M5J3Z8	Comt.	Scat.	0.700
A0A0M3QY10	Dbus_chrXg1047	A0A0M3QY10	A0A0M4EJB1	Comt.	CG7039.	0.600
A0A0M3QY50	Dbus_chr2Lg859	A0A0M3QY50	A0A0M5J1F6	Sbf.	Mtm.	0.936
A0A0M3QYL9	A0A0M4EG86	A0A0M3QYL9	A0A0M4EG86	CG8202.	Fidipidine.	0.839
A0A0M3QYL9	A0A0M5IXZ8	A0A0M3QYL9	A0A0M5IXZ8	CG8202.	Vps35.	0.407
A0A0M4E194	A0A0M4F162	A0A0M4E194	A0A0M4F162	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Mop.	0.742
A0A0M4E194	A0A0M5IXZ8	A0A0M4E194	A0A0M5IXZ8	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Vps35.	0.538
A0A0M4E194	Dbus_chr2Rg744	A0A0M4E194	A0A0M4EC04	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Rho1.	0.440
A0A0M4E194	Dbus_chr2Rg875	A0A0M4E194	A0A0M4E902	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Rho1.	0.440
A0A0M4E194	Dbus_chr3Rg216	A0A0M4E194	A0A0M4ECQ3	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Past1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.424
A0A0M4E194	Dbus_chr3Rg512	A0A0M4E194	A0A0M4F2R1	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Rab11.	0.414
A0A0M4E194	Dbus_chr3Rg920	A0A0M4E194	A0A0M4F4A9	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Snx3.	0.554
A0A0M4E194	Dbus_chrXg1424	A0A0M4E194	A0A0M5J8C8	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	Mer.	0.455
A0A0M4E607	A0A0M4EG86	A0A0M4E607	A0A0M4EG86	Wash.	Fidipidine.	0.476
A0A0M4E607	A0A0M5IXZ8	A0A0M4E607	A0A0M5IXZ8	Wash.	Vps35.	0.548
A0A0M4E6Y4	A0A0M4EM34	A0A0M4E6Y4	A0A0M4EM34	CG18659.	Rab8.	0.533
A0A0M4E6Y4	Dbus_chrXg318	A0A0M4E6Y4	A0A0M4F834	CG18659.	Rab35.	0.985