STRINGSTRING
e(y)2 e(y)2 Dbus_chrXg204 Dbus_chrXg204 A0A0M5J4Z4 A0A0M5J4Z4 A0A0M5IYR9 A0A0M5IYR9 A0A0M4ESD8 A0A0M4ESD8 e(y)2-2 e(y)2-2 Dbus_chr3Rg285 Dbus_chr3Rg285 A0A0M4EMZ1 A0A0M4EMZ1 A0A0M4EJG7 A0A0M4EJG7 A0A0M4EAP7 A0A0M4EAP7 Dbus_chr3Lg532 Dbus_chr3Lg532 Dbus_chrXg499 Dbus_chrXg499 A0A0M3QY59 A0A0M3QY59 Dbus_chr3Rg179 Dbus_chr3Rg179 Sgf11 Sgf11
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
e(y)2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (108 aa)
Dbus_chrXg204Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (963 aa)
A0A0M5J4Z4Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (436 aa)
A0A0M5IYR9E3 ubiquitin protein ligase. (1064 aa)
A0A0M4ESD8Inhibitor of growth protein. (274 aa)
e(y)2-2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the AMEX and the SAGA complexes. The SAGA complex is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Involved in t [...] (106 aa)
Dbus_chr3Rg285Histone-lysine N-methyltransferase trithorax; Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo. (3671 aa)
A0A0M4EMZ1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (479 aa)
A0A0M4EJG7Inhibitor of growth protein. (466 aa)
A0A0M4EAP7Probable lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. (863 aa)
Dbus_chr3Lg532Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (529 aa)
Dbus_chrXg499Inhibitor of growth protein. (561 aa)
A0A0M3QY59RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
Dbus_chr3Rg179Histone-lysine N-methyltransferase, H3 lysine-79 specific. (2073 aa)
Sgf11SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA- dependent manner. Bind [...] (205 aa)
Your Current Organism:
Drosophila busckii
NCBI taxonomy Id: 30019
Other names: D. busckii
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