(8 nodes) Small ribosomal subunit network (Shigella dysenteriae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsE	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family. (167 aa)
	rpsS	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
	rpsG	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
	rpsB	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family. (241 aa)
	yfiA	Putative yhbH sigma 54 modulator; Code: J; COG: COG1544. (113 aa)
	yhbH	Probable sigma-54 modulation protein; Code: J; COG: COG1544. (95 aa)
	rpsL	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa)
	rpsD	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpsB	rpsD	SDY_0185	SDY_3472	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.998
rpsB	rpsE	SDY_0185	SDY_3479	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.998
rpsB	rpsG	SDY_0185	SDY_3502	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999
rpsB	rpsL	SDY_0185	SDY_3503	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.998
rpsB	rpsS	SDY_0185	SDY_3492	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.998
rpsB	yfiA	SDY_0185	SDY_2768	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	Putative yhbH sigma 54 modulator; Code: J; COG: COG1544.	0.699
rpsB	yhbH	SDY_0185	SDY_3384	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	Probable sigma-54 modulation protein; Code: J; COG: COG1544.	0.827
rpsD	rpsB	SDY_3472	SDY_0185	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	0.998
rpsD	rpsE	SDY_3472	SDY_3479	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	0.999
rpsD	rpsG	SDY_3472	SDY_3502	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.998
rpsD	rpsL	SDY_3472	SDY_3503	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.998
rpsD	rpsS	SDY_3472	SDY_3492	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpsD	yfiA	SDY_3472	SDY_2768	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	Putative yhbH sigma 54 modulator; Code: J; COG: COG1544.	0.711
rpsD	yhbH	SDY_3472	SDY_3384	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	Probable sigma-54 modulation protein; Code: J; COG: COG1544.	0.837
rpsE	rpsB	SDY_3479	SDY_0185	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S2; Code: J; COG: COG0052; Belongs to the universal ribosomal protein uS2 family.	0.998
rpsE	rpsD	SDY_3479	SDY_3472	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rpsE	rpsG	SDY_3479	SDY_3502	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.998
rpsE	rpsL	SDY_3479	SDY_3503	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.998
rpsE	rpsS	SDY_3479	SDY_3492	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpsE	yfiA	SDY_3479	SDY_2768	30S ribosomal subunit protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family.	Putative yhbH sigma 54 modulator; Code: J; COG: COG1544.	0.717