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| | yjjW | Putative activating enzyme; Code: O; COG: COG1180. (287 aa) |
| | thrA | Homoserine dehydrogenase I; Code: E; COG: COG0527; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa) |
| | yacK | Conserved hypothetical protein; Code: Q; COG: COG2132; orf. (516 aa) |
| | lytB | Control of stringent response; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | caiA | Probable carnitine operon oxidoreductase; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. (380 aa) |
| | fixA | FixA; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (268 aa) |
| | fixB | FixB; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (313 aa) |
| | fixC | FixC; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (349 aa) |
| | yabF | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa) |
| | folA | Dihydrofolate reductase type I; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (159 aa) |
| | pdxA | Pyridoxine biosynthesis; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (329 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (364 aa) |
| | guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (347 aa) |
| | aceE | Pyruvate dehydrogenase decarboxylase component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | lpdA | Lipoamide dehydrogenase (NADH); Component of 2-oxodehydrogenase and pyruvate complexes; L-protein of glycine cleavage complex; Code: C; COG: COG1249. (474 aa) |
| | yaeM | Putative ATP-binding component of a transport system; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (398 aa) |
| | yafB | Putative aldose reductase; Code: R; COG: COG0656. (255 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | apbA | ApbA; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa) |
| | yajO | Putative NAD(P)H-dependent xylose reductase; Code: C; COG: COG0667. (324 aa) |
| | ribD | Bifunctional pyrimidine deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (367 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (269 aa) |
| | ybbO | Putative oxidoreductase; Code: IQR; COG: COG1028. (269 aa) |
| | proA | Gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (417 aa) |
| | nfnB | Oxygen-insensitive NAD(P)H nitroreductase; Code: C; COG: COG0778. (217 aa) |
| | tauD | Taurine dioxygenase; 2-oxoglutarate-dependent; Code: Q; COG: COG2175. (283 aa) |
| | entA | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Enterochelin biosynthesis; Code: IQR; COG: COG1028. (248 aa) |
| | ybdH | Putative oxidoreductase; Code: C; COG: COG0371. (362 aa) |
| | ahpC | Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa) |
| | ahpF | Alkyl hydroperoxide reductase, F52a subunit; Detoxification of hydroperoxides; Code: O; COG: COG3634. (531 aa) |
| | yleB | Conserved hypothetical protein; Code: HC; COG: COG0654; orf. (391 aa) |
| | fldA | Flavodoxin 1; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa) |
| | sdhC | Succinate dehydrogenase; Cytochrome b556; Code: C; COG: COG2009. (129 aa) |
| | sdhD | Succinate dehydrogenase, hydrophobic subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; Code: C; COG: COG1053; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | Succinate dehydrogenase, iron sulfur protein; Code: C; COG: COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa) |
| | sucA | 2-oxoglutarate dehydrogenase, decarboxylase component; Code: C; COG: COG0567. (933 aa) |
| | cydA | Cytochrome d terminal oxidase, polypeptide subunit I; Code: C; COG: COG1271. (523 aa) |
| | mdaA | Modulator of drug activity A; Code: C; COG: COG0778; Belongs to the flavin oxidoreductase frp family. (240 aa) |
| | grxA | Glutaredoxin1 redox coenzyme for glutathione-dependent ribonucleotide reductase; Code: O; COG: COG0695. (85 aa) |
| | ybiY | Putative pyruvate formate-lyase 2 activating enzyme; Code: O; COG: COG1180. (308 aa) |
| | dps | Global regulator; During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co-crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. Dps also protects the cell from UV and gamma irradiation, iron and copper toxicity, [...] (167 aa) |
| | ybiX | Putative enzyme; Code: S; COG: COG3128. (237 aa) |
| | ybiC | Putative dehydrogenase; Code: C; COG: COG2055; Belongs to the LDH2/MDH2 oxidoreductase family. (361 aa) |
| | alkB | DNA repair system specific for alkylated DNA; Code: L; COG: COG3145. (216 aa) |
| | yojH | Conserved hypothetical protein; Code: R; COG: COG0579; orf. (548 aa) |
| | napA | Probable nitrate reductase 3; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa) |
| | dsbE | Disulfide oxidoreductase; Possibly involved in biogenesis of cytochrome c; Code: OC; COG: COG0526. (185 aa) |
| | yeiQ | Putative oxidoreductase; Code: G; COG: COG0246; Belongs to the mannitol dehydrogenase family. (469 aa) |
| | pyrD | Dihydro-orotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa) |
| | hyaA | Hydrogenase-1 small subunit; Code: C; COG: COG1740. (372 aa) |
| | hyaB | Hydrogenase-1 large subunit; Code: C; COG: COG0374. (568 aa) |
| | hyaC | Probable Ni/Fe-hydrogenase 1 b-type cytochrome subunit; Code: C; COG: COG1969. (235 aa) |
| | appC | Probable third cytochrome oxidase, subunit I; Original product: nickel incorporation into hydrogenase-1 proteins. (514 aa) |
| | wrbA | Affects association of trp repressor and operator; Code: R; COG: COG0655. (198 aa) |
| | rutF | Conserved hypothetical protein; Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway. (152 aa) |
| | rutE | Putative enzyme; May reduce toxic product malonic semialdehyde to 3- hydroxypropionic acid, which is excreted; Belongs to the nitroreductase family. HadB/RutE subfamily. (196 aa) |
| | rutC | Conserved hypothetical protein; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. (128 aa) |
| | rutA | Conserved hypothetical protein; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. RutA subfamily. (382 aa) |
| | ycdW | Putative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. (325 aa) |
| | msrQ | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. MsrQ [...] (211 aa) |
| | msrP | Putative reductase; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone SurA and the lipoprotein Pal. The catalytic su [...] (334 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | bisZ | Biotin sulfoxide reductase 2; Code: C; COG: COG0243. (786 aa) |
| | dsbB | DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa) |
| | dadA | D-amino acid dehydrogenase subunit; Oxidative deamination of D-amino acids; Belongs to the DadA oxidoreductase family. (432 aa) |
| | hemA | 5-aminolevulinate synthesis enzyme, alternate pathway; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa) |
| | narG | Nitrate reductase 1, alpha subunit; Code: C; COG: COG5013; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa) |
| | narH | Nitrate reductase 1, beta subunit; Code: C; COG: COG1140. (512 aa) |
| | narI | Nitrate reductase 1, cytochrome b(NR), gamma subunit; Code: C; COG: COG2181. (225 aa) |
| | adhE | Aldehyde-alcohol dehydrogenase; Code: C; COG: COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa) |
| | yciK | Putative oxidoreductase; Code: IQR; COG: COG1028. (252 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase (NADH); Code: I; COG: COG0623. (262 aa) |
| | tpx | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (168 aa) |
| | ydbK | Putative oxidoreductase, Fe-S subunit; Code: C; COG: COG0674. (1174 aa) |
| | ldhA | Fermentative D-lactate dehydrogenase, NAD-dependent; Code: CHR; COG: COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | ydiB | Putative oxidoreductase; The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD. (297 aa) |
| | SDY_1486 | Putative aldehyde reductase; Code: R; COG: COG0656. (283 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase A; Code: G; COG: COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | yeaA | Conserved hypothetical protein; Code: O; COG: COG0229; orf; Belongs to the MsrB Met sulfoxide reductase family. (137 aa) |
| | SDY_1491 | Putative oxidoreductase; Code: ER; COG: COG1063. (358 aa) |
| | ydjJ | Putative oxidoreductase; Code: ER; COG: COG1063. (335 aa) |
| | ydjA | Conserved hypothetical protein; Code: C; COG: COG0778; orf. (183 aa) |
| | gdhA | NADP-specific glutamate dehydrogenase; Code: E; COG: COG0334; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa) |
| | ynjA | Conserved hypothetical protein; Code: S; COG: COG2128; orf. (182 aa) |
| | astD | Putative aldehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate. (333 aa) |
| | ydgB | Putative oxidoreductase; Catalyzes the reduction of dihydromonapterin to tetrahydromonapterin. Also has lower activity with dihydrofolate. (240 aa) |
| | pntA | Pyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa) |
| | pntB | Pyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa) |
| | ydfG | Putative oxidoreductase; Code: R; COG: COG4221; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | fdnI | Formate dehydrogenase-N, nitrate-inducible, cytochrome B556(Fdn) gamma subunit; Code: C; COG: COG2864. (217 aa) |
| | adhP | Alcohol dehydrogenase; Code: R; COG: COG1064. (375 aa) |
| | osmC | Osmotically inducible protein; Code: O; COG: COG1764. (143 aa) |
| | SDY_1632 | Putative aldehyde dehydrogenase; Code: C; COG: COG1012. (470 aa) |
| | narY | Cryptic nitrate reductase 2, beta subunit; Code: C; COG: COG1140. (507 aa) |
| | narV | Cryptic nitrate reductase 2, gamma subunit; Code: C; COG: COG2181. (226 aa) |
| | SDY_1658 | Putative oxidoreductase, major subunit; Code: C; COG: COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (759 aa) |
| | ydiJ | Putative oxidase; Code: C; COG: COG0277. (1018 aa) |
| | yeaU | Putative tartrate dehydrogenase; Code: CE; COG: COG0473. (361 aa) |
| | yeaW | Conserved hypothetical protein; Converts carnitine to trimethylamine and malic semialdehyde. (374 aa) |
| | yeaX | Putative diogenase beta subunit; Converts carnitine to trimethylamine and malic semialdehyde. (321 aa) |
| | yncB | Putative oxidoreductase; Code: R; COG: COG2130. (376 aa) |
| | patD | Putative aldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa) |
| | cybB | Cytochrome b(561); Code: C; COG: COG3038. (188 aa) |
| | acpD | Acyl carrier protein phosphodiesterase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (201 aa) |
| | SDY_1783 | Putative oxidoreductase; Code: I; COG: COG1960. (401 aa) |
| | ydiS | YdiS; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (429 aa) |
| | btuE | Vitamin B12 transport protein; Non-specific peroxidase that can use thioredoxin or glutathione as a reducing agent. (183 aa) |
| | hdhA | NAD-dependent 7alpha-hydroxysteroid dehydrogenase; Dehydroxylation of bile acids; Code: IQR; COG: COG1028. (255 aa) |
| | rsxB | Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (192 aa) |
| | rsxC | Putative membrane protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (772 aa) |
| | rsxG | Conserved hypothetical protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the RnfG family. (206 aa) |
| | pdxH | Pyridoxinephosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (218 aa) |
| | SDY_1871 | Conserved hypothetical protein; Code: R; COG: COG4989; orf. (298 aa) |
| | nemA | N-ethylmaleimide reductase; Code: C; COG: COG1902. (343 aa) |
| | ydhD | Conserved hypothetical protein; Code: O; COG: COG0278; orf; Belongs to the glutaredoxin family. Monothiol subfamily. (115 aa) |
| | sodB | Superoxide dismutase, iron; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (193 aa) |
| | ydhU | Conserved hypothetical protein; Code: C; COG: COG4117; orf. (261 aa) |
| | ordL | Probable oxidoreductase; Code: E; COG: COG0665. (426 aa) |
| | icdA | Isocitrate dehydrogenase; Code: C; COG: COG0538. (416 aa) |
| | ndh | Respiratory NADH dehydrogenase; Code: C; COG: COG1252. (434 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | grxB | Code: O; COG: COG2999. (215 aa) |
| | solA | Sarcosine oxidase-like protein; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily. (372 aa) |
| | SDY_2140 | Putative oxidoreductase; Code: ER; COG: COG0493. (365 aa) |
| | yohI | Putative regulator protein; Code: J; COG: COG0042. (191 aa) |
| | yohF | Putative oxidoreductase; Code: IQR; COG: COG1028. (253 aa) |
| | dld | D-lactate dehydrogenase, FAD protein; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa) |
| | rfbD | dTDP-6-deoxy-L-mannose-dehydrogenase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (299 aa) |
| | gnd | Gluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | ugd | UDP-glucose 6-dehydrogenase; Code: M; COG: COG1004. (388 aa) |
| | hisD | L-histidinal:NAD+ oxidoreductase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (434 aa) |
| | gatD | Galactitol-1-phosphate dehydrogenase; Code: ER; COG: COG1063. (346 aa) |
| | yceA | Conserved hypothetical protein; Code: R; COG: COG1054; orf; Belongs to the UPF0176 family. (350 aa) |
| | SDY_2312 | Putative cytochrome; Code: C; COG: COG3038. (188 aa) |
| | ycbP | Conserved hypothetical protein; Code: R; COG: COG0431; orf. (191 aa) |
| | SDY_2321 | Hypothetical protein. (182 aa) |
| | SDY_2322 | Hypothetical protein. (152 aa) |
| | pflA | Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa) |
| | dmsA | Anaerobic dimethyl sulfoxide reductase subunit A; Code: C; COG: COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (785 aa) |
| | trxB | Thioredoxin reductase; Code: O; COG: COG0492. (321 aa) |
| | ybjW | Putative prismane; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (552 aa) |
| | SDY_2391 | Putative enzyme; Code: C; COG: COG1018. (322 aa) |
| | poxB | Pyruvate oxidase; Code: EH; COG: COG0028; Belongs to the TPP enzyme family. (572 aa) |
| | nrdA | Ribonucleoside diphosphate reductase 1, alpha subunit, B1; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (761 aa) |
| | nrdB | Ribonucleoside-diphosphate reductase 1, beta subunit, B2; Code: F; COG: COG0208. (376 aa) |
| | glpA | Sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit; Code: C; COG: COG0578; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (542 aa) |
| | glpB | Sn-glycerol-3-phosphate dehydrogenase (anaerobic), membrane anchor subunit; Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor. (419 aa) |
| | arnA | Putative transformylase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the C-terminal section; belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. (544 aa) |
| | nuoN | NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (425 aa) |
| | nuoM | NADH dehydrogenase I chain M; Code: C; COG: COG1008. (509 aa) |
| | nuoL | NADH dehydrogenase I chain L; Code: CP; COG: COG1009. (613 aa) |
| | nuoK | NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoJ | NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa) |
| | nuoI | NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa) |
| | nuoH | NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa) |
| | nuoG | NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa) |
| | nuoF | NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa) |
| | nuoE | NADH dehydrogenase I chain E; Code: C; COG: COG1905. (166 aa) |
| | nuoC | NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (600 aa) |
| | nuoB | NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa) |
| | nuoA | NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa) |
| | usg | Putative PTS system enzyme II A component; Code: E; COG: COG0136; Belongs to the aspartate-semialdehyde dehydrogenase family. (337 aa) |
| | pdxB | Erythronate-4-phosphate dehyrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (378 aa) |
| | mnmC | Putative peptidase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (688 aa) |
| | fadJ | Putative enzyme; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa) |
| | SDY_2629 | Conserved hypothetical protein; Code: P; COG: COG2837; orf. (308 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (299 aa) |
| | SDY_2645 | Putative multimodular enzyme; Code: C; COG: COG0281. (759 aa) |
| | yffG | Putative oxidoreductase, Fe-S subunit; Code: ER; COG: COG0493. (659 aa) |
| | bcp | Bacterioferritin comigratory protein; Code: O; COG: COG1225. (156 aa) |
| | hyfB | Hydrogenase 4 membrane subunit; Code: CP; COG: COG0651. (672 aa) |
| | hyfG | Hydrogenase 4 subunit; Code: C; COG: COG3261. (571 aa) |
| | hyfI | Hydrogenase 4 Fe-S subunit; Code: C; COG: COG3260. (252 aa) |
| | SDY_2684 | Putative oxidoreductase; Code: P; COG: COG1393. (119 aa) |
| | guaB | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa) |
| | gcpE | Conserved hypothetical protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (372 aa) |
| | fdx | [2FE-2S] ferredoxin, electron carrer protein; Code: C; COG: COG0633. (111 aa) |
| | hmpA | Dihydropteridine reductase, ferrisiderophore reductase activity; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily. (396 aa) |
| | tyrA | Chorismate mutase-T; Prephenate dehydrogenase; Code: E; COG: COG0287. (373 aa) |
| | nadB | Quinolinate synthetase, B protein; Catalyzes the oxidation of L-aspartate to iminoaspartate. (540 aa) |
| | trxC | Putative thioredoxin-like protein; Code: OC; COG: COG0526; Belongs to the thioredoxin family. (139 aa) |
| | SDY_2865 | Conserved hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (143 aa) |
| | nrdH | Glutaredoxin-like protein; Hydrogen donor; Code: O; COG: COG0695. (81 aa) |
| | nrdE | Ribonucleoside-diphosphate reductase 2, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (616 aa) |
| | nrdF | Ribonucleoside-diphosphate reductase 2, beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (322 aa) |
| | srlD | Sorbitol-6-phosphate dehydrogenase; Code: IQR; COG: COG1028; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa) |
| | norV | Putative flavodoxin; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family. (479 aa) |
| | ygbD | Putative oxidoreductase; One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase. (377 aa) |
| | hycF | Probable iron-sulfur protein of hydrogenase 3; Part of FHL complex; Code: C; COG: COG1143. (180 aa) |
| | hycE | Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261. (569 aa) |
| | cysH | 3'-phosphoadenosine 5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa) |
| | cysI | Sulfite reductase, alpha subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa) |
| | cysJ | Sulfite reductase (NADPH), flavoprotein beta subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component; Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (599 aa) |
| | ygcN | Conserved hypothetical protein; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (433 aa) |
| | SDY_2974 | Conserved hypothetical protein; Code: C; COG: COG0277; orf. (457 aa) |
| | ygcW | Putative oxidoreductase; Code: IQR; COG: COG1028. (261 aa) |
| | yqcD | Conserved hypothetical protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (282 aa) |
| | fucO | L-1,2-propanediol oxidoreductase; Code: C; COG: COG1454. (383 aa) |
| | Tas | Conserved hypothetical protein; Code: C; COG: COG0667; orf. (346 aa) |
| | yqhE | Conserved hypothetical protein; Code: R; COG: COG0656; orf. (236 aa) |
| | yqhD | Putative oxidoreductase; Code: C; COG: COG1979. (387 aa) |
| | yghA | Putative oxidoreductase; Code: IQR; COG: COG1028. (294 aa) |
| | SDY_3076 | Putative hydrogenase subunit; Code: C; COG: COG1740. (372 aa) |
| | hybC | Probable large subunit, hydrogenase-2; Code: C; COG: COG0374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa) |
| | yggW | Putative oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (378 aa) |
| | SDY_3145 | Putative oxidoreductase; Code: ER; COG: COG1063. (329 aa) |
| | epd | D-erythrose 4-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate. (339 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Code: HE; COG: COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | ubiH | UbiH; 2-octaprenyl-6-methoxyphenol--> 2-octaprenyl-6-methoxy-1, 4-benzoquinone; Code: HC; COG: COG0654. (392 aa) |
| | visC | Conserved hypothetical protein; Code: HC; COG: COG0654; orf. (400 aa) |
| | gcvP | Glycine decarboxylase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa) |
| | fldB | Flavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (173 aa) |
| | dsbC | Protein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (236 aa) |
| | sufI | Suppressor of ftsI; Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress. (470 aa) |
| | yqjH | Conserved hypothetical protein; Code: P; COG: COG2375; orf. (254 aa) |
| | ygjL | Putative NADPH dehydrogenase; Code: C; COG: COG1902. (672 aa) |
| | yhaE | Putative dehydrogenase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily. (299 aa) |
| | yraR | Conserved hypothetical protein; Code: MG; COG: COG0702; orf. (226 aa) |
| | yhbW | Putative enzyme; Code: C; COG: COG2141. (335 aa) |
| | gltB | Glutamate synthase, large subunit; Code: E; COG: COG0069. (1486 aa) |
| | gltD | Glutamate synthase, small subunit; Code: ER; COG: COG0493. (472 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | yhdH | Putative dehydrogenase; Code: CR; COG: COG0604. (324 aa) |
| | yhdG | Putative dehydrogenase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa) |
| | aroE | Dehydroshikimate reductase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | bfr | Bacterioferrin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (158 aa) |
| | yheR | Putative NAD(P)H oxidoreductase; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (184 aa) |
| | nirB | Nitrite reductase (NAD(P)H) subunit; Code: C; COG: COG1251; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa) |
| | nirD | Nitrite reductase (NAD(P)H) subunit; Code: PR; COG: COG2146. (108 aa) |
| | cysG | Uroporphyrinogen III methylase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (457 aa) |
| | arsC | Arsenate reductase; Code: P; COG: COG1393. (141 aa) |
| | gor | Glutathione oxidoreductase; Code: C; COG: COG1249. (450 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa) |
| | glpD | Sn-glycerol-3-phosphate dehydrogenase (aerobic); Code: C; COG: COG0578; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (501 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (342 aa) |
| | metL | Aspartokinase II and homoserine dehydrogenase II; Code: E; COG: COG0527; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Code: E; COG: COG0685; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) |
| | gldA | Glycerol dehydrogenase, (NAD); Code: C; COG: COG0371. (380 aa) |
| | pflC | Probable pyruvate formate lyase activating enzyme 2; Code: O; COG: COG1180. (292 aa) |
| | argC | N-acetyl-gamma-glutamylphosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | udhA | Putative oxidoreductase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (444 aa) |
| | fpr | ferredoxin-NADP reductase; Code: C; COG: COG1018. (248 aa) |
| | sodA | Superoxide dismutase, manganese; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (206 aa) |
| | fdoG | Formate dehydrogenase-O, major subunit; Code: C; COG: COG0243. (1016 aa) |
| | fdoI | Formate dehydrogenase, cytochrome B556 (FDO) subunit; Code: C; COG: COG2864. (211 aa) |
| | hemN | O2-independent coproporphyrinogen III oxidase; Code: H; COG: COG0635; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (459 aa) |
| | dsbA | Protein disulfide isomerase I; Essential for cytochrome c synthesis and formate-dependent reduction; Code: OC; COG: COG0526. (208 aa) |
| | hemG | Protoporphyrin oxidase; Code: CH; COG: COG4635. (181 aa) |
| | fadB | Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | ubiB | Flavin reductase; NADPH:flavin oxidoreductase; Code: HC; COG: COG0543. (233 aa) |
| | wecC | UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa) |
| | trxA | Thioredoxin 1; Code: OC; COG: COG0526; Belongs to the thioredoxin family. (127 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa) |
| | lldD | L-lactate dehydrogenase; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (396 aa) |
| | gpsA | Glycerol-3-phosphate dehydrogenase (NAD+); Code: C; COG: COG0240; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa) |
| | grxC | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (83 aa) |
| | tdh | Threonine dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. (341 aa) |
| | melA | Alpha-galactosidase; Code: G; COG: COG1486. (451 aa) |
| | yidF | Putative transcriptional regulator; Code: R; COG: COG0641. (165 aa) |
| | SDY_4168 | Putative 6-phospho-beta-glucosidase; Code: G; COG: COG1486. (440 aa) |
| | cybC | Cytochrome b(562); Code: C; COG: COG3783. (100 aa) |
| | nrdG | Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa) |
| | nrdD | Anaerobic ribonucleoside-triphosphate reductase; Code: F; COG: COG1328. (712 aa) |
| | yjgI | Putative oxidoreductase; Code: IQR; COG: COG1028. (237 aa) |
| | yjgB | Putative oxidoreductase; Code: R; COG: COG1064. (353 aa) |
| | SDY_4317 | Putative L-sorbose 1-phosphate dehydrogenase; Code: ER; COG: COG1063. (409 aa) |
| | yiaE | Putative dehydrogenase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (328 aa) |
| | bisC | Biotin sulfoxide reductase; Code: C; COG: COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (739 aa) |
| | frdD | Fumarate reductase, anaerobic; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | frdC | Fumarate reductase, anaerobic; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdB | Fumarate reductase, anaerobic, iron-sulfur protein subunit; Code: C; COG: COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa) |
| | frdA | Fumarate reductase, anaerobic, flavoprotein subunit; Code: C; COG: COG1053. (602 aa) |
| | aidB | Putative acyl coenzyme A dehydrogenase; Code: I; COG: COG1960. (542 aa) |
| | yjeS | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (379 aa) |
| | dsbD | Thiol:disulfide interchange protein; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (565 aa) |
| | msrA | Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (212 aa) |
| | qor | Quinone oxidoreductase; Code: CR; COG: COG0604. (327 aa) |
| | yjbN | Conserved hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (345 aa) |
