STRINGSTRING
fecC fecC fecE fecE yjgQ yjgQ yjgP yjgP SDY_4206 SDY_4206 phnD phnD pstS pstS atpC atpC yadH yadH fhuC fhuC tsx tsx tauA tauA fepC fepC ybeC ybeC gltK gltK sdhC sdhC modF modF potG potG gsiB gsiB glnP glnP ybhF ybhF ybhS ybhS ybhR ybhR ompC ompC yejA yejA ompA ompA yccZ yccZ csgE csgE csgF csgF yecS yecS yebI yebI oppA oppA SDY_1409 SDY_1409 sitD sitD sitC sitC sitB sitB SDY_1519 SDY_1519 SDY_1521 SDY_1521 SDY_1522 SDY_1522 SDY_1564 SDY_1564 SDY_1602 SDY_1602 SDY_1611 SDY_1611 sapA sapA SDY_1663 SDY_1663 SDY_1733 SDY_1733 potA potA ndh ndh yehZ yehZ ompF ompF SDY_2383 SDY_2383 artQ artQ artM artM nuoF nuoF atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB atpI atpI tatA tatA SDY_3906 SDY_3906 yigU yigU btuB btuB nikA nikA livF livF ugpE ugpE nuoC nuoC nuoE nuoE yhdY yhdY yhbG yhbG yrbE yrbE SDY_3217 SDY_3217 cysA cysA hisQ hisQ hisM hisM dppA dppA dppF dppF frdC frdC frdD frdD fecA fecA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fecCCitrate-dependent iron(III) transport protein cytosolic; Code: P; COG: COG0609; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (331 aa)
fecEATP-binding component of citrate-dependent iron(III) transport protein; Code: PH; COG: COG1120. (255 aa)
yjgQConserved hypothetical protein; Code: R; COG: COG0795; orf. (361 aa)
yjgPConserved hypothetical protein; Code: R; COG: COG0795; orf. (366 aa)
SDY_4206Hypothetical protein; Code: L; COG: COG3328; orf. (79 aa)
phnDPeriplasmic binding protein component of Pn transporter; Code: P; COG: COG3221. (338 aa)
pstSHigh-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
atpCMembrane-bound ATP synthase, F1 sector, epsilon-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa)
yadHConserved hypothetical protein; Code: V; COG: COG0842; orf. (256 aa)
fhuCATP-binding component of hydroxymate-dependent iron transport; Code: PH; COG: COG1120. (265 aa)
tsxNucleoside channel; Receptor of phage T6 and colicin K; Code: M; COG: COG3248. (294 aa)
tauATaurine transport system periplasmic protein; Code: P; COG: COG4521. (320 aa)
fepCATP-binding component of ferric enterobactin transport; Code: PH; COG: COG1120. (271 aa)
ybeCConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA; Belongs to the TatA/E family. TatE subfamily. (67 aa)
gltKGlutamate/aspartate transport system permease; Code: E; COG: COG0765. (224 aa)
sdhCSuccinate dehydrogenase; Cytochrome b556; Code: C; COG: COG2009. (129 aa)
modFATP-binding component of molybdate transport system; Code: P; COG: COG1119. (490 aa)
potGATP-binding component of putrescine transport system; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
gsiBPutative transport protein; Part of the ABC transporter complex GsiABCD involved in glutathione import. Binds glutathione. (512 aa)
glnPGlutamine high-affinity transport system, membrane component; Code: E; COG: COG0765. (219 aa)
ybhFPutative ATP-binding component of a transport system; Code: V; COG: COG1131. (583 aa)
ybhSConserved hypothetical protein; Code: V; COG: COG0842; orf. (377 aa)
ybhRConserved hypothetical protein; Code: V; COG: COG0842; orf. (368 aa)
ompCOuter membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family. (375 aa)
yejAConserved hypothetical protein; Code: E; COG: COG4166; orf. (606 aa)
ompAOuter membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (350 aa)
yccZPutative function in exopolysaccharide production; Code: M; COG: COG1596. (379 aa)
csgECurli production assembly/transport component; 2nd curli operon. (129 aa)
csgFCurli production assembly/transport component; 2nd curli operon. (138 aa)
yecSPutative transport system permease protein; Formerly yecC; Code: E; COG: COG0765. (222 aa)
yebIConserved hypothetical protein; Code: P; COG: COG1108; orf. (261 aa)
oppAOppA; Oligopeptide transport; periplasmic binding protein; Code: E; COG: COG4166. (543 aa)
SDY_1409Putative transport periplasmic protein; Code: E; COG: COG4166. (544 aa)
sitDIron transport protein, inner membrane component; Code: P; COG: COG1108. (285 aa)
sitCIron transport protein, inner membrane component; Code: P; COG: COG1108. (285 aa)
sitBIron transport protein, ATP-binding component; Code: P; COG: COG1121. (275 aa)
SDY_1519Putative ATP-binding component of a transport system; Code: R; COG: COG4136. (217 aa)
SDY_1521Hypothetical protein. (189 aa)
SDY_1522Hypothetical protein. (148 aa)
SDY_1564Putative chloride channel; Code: P; COG: COG0038. (445 aa)
SDY_1602Hypothetical protein. (84 aa)
SDY_1611Putative ATP-binding component of a transport system; Code: EP; COG: COG1124; Belongs to the ABC transporter superfamily. (308 aa)
sapASapA; Similar to Salmonella peptide transport periplasmic protein; Code: E; COG: COG4166. (547 aa)
SDY_1663Hypothetical protein; Belongs to the Gram-negative porin family. (102 aa)
SDY_1733Putative ATP-binding component of a transport system; Code: E; COG: COG3842; Belongs to the ABC transporter superfamily. (337 aa)
potAATP-binding component of spermidine/putrescine transport; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
ndhRespiratory NADH dehydrogenase; Code: C; COG: COG1252. (434 aa)
yehZPutative transport system permease protein; Code: M; COG: COG1732. (305 aa)
ompFOuter membrane protein 1a (Ia;b;F); Code: M; COG: COG3203; Belongs to the Gram-negative porin family. (362 aa)
SDY_2383Putative membrane protein; Code: M; COG: COG0845; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (358 aa)
artQArginine 3rd transport system permease protein; Code: E; COG: COG4215. (238 aa)
artMArginine 3rd transport system permease protein; Code: E; COG: COG4160. (222 aa)
nuoFNADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
atpDMembrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa)
atpGMembrane-bound ATP synthase, F1 sector, gamma-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa)
atpAMembrane-bound ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa)
atpHMembrane-bound ATP synthase, F1 sector, delta-subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (177 aa)
atpFMembrane-bound ATP synthase, F0 sector, subunit b; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (156 aa)
atpEMembrane-bound ATP synthase, F0 sector, subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (79 aa)
atpBMembrane-bound ATP synthase, F0 sector, subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (271 aa)
atpIMembrane-bound ATP synthase; Dispensable protein; affects expression of atpB; Code: C; COG: COG3312. (130 aa)
tatAConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (103 aa)
SDY_3906Conserved hypothetical protein; Code: U; COG: COG1826; orf. (145 aa)
yigUConserved hypothetical protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (258 aa)
btuBOuter membrane receptor for transport of vitamin B12, E colicins, and bacteriophage BF23; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
nikAPeriplasmic binding protein for nickel; Code: E; COG: COG0747. (524 aa)
livFATP-binding component of leucine transport; Code: E; COG: COG0410; Belongs to the ABC transporter superfamily. (241 aa)
ugpESn-glycerol 3-phosphate transport protein, integral membrane protein; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
nuoCNADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (600 aa)
nuoENADH dehydrogenase I chain E; Code: C; COG: COG1905. (166 aa)
yhdYPutative transport system permease protein; Code: E; COG: COG0765. (368 aa)
yhbGPutative ATP-binding component of a transport system; Code: R; COG: COG1137. (241 aa)
yrbEConserved hypothetical protein; Code: Q; COG: COG0767; orf. (260 aa)
SDY_3217Putative transport periplasmic protein; Code: E; COG: COG4166. (535 aa)
cysAATP-binding component of sulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
hisQHistidine transport system permease protein; Code: E; COG: COG4215. (228 aa)
hisMHistidine transport, membrane protein M; Code: E; COG: COG4160. (238 aa)
dppADipeptide transport protein; Code: E; COG: COG0747. (535 aa)
dppFPutative ATP-binding component of dipeptide transport system; Code: E; COG: COG4608; Belongs to the ABC transporter superfamily. (334 aa)
frdCFumarate reductase, anaerobic; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdDFumarate reductase, anaerobic; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
fecACitrate-dependent iron transport, outer membrane receptor; Code: P; COG: COG4772. (774 aa)
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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