19 items (Shigella dysenteriae) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Predicted Interactions

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Your Input:
	hyfG	Hydrogenase 4 subunit; Code: C; COG: COG3261. (571 aa)
	nuoJ	NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
	nuoI	NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
	nuoH	NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
	nuoG	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
	nuoF	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (445 aa)
	nuoE	NADH dehydrogenase I chain E; Code: C; COG: COG1905. (166 aa)
	nuoC	NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. (600 aa)
	nuoB	NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
	nuoA	NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
	nuoK	NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
	yfhL	Conserved hypothetical protein; Code: C; COG: COG1145; orf. (86 aa)
	hycE	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261. (569 aa)
	nuoN	NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (425 aa)
	ndh	Respiratory NADH dehydrogenase; Code: C; COG: COG1252. (434 aa)
	ydbK	Putative oxidoreductase, Fe-S subunit; Code: C; COG: COG0674. (1174 aa)
	folK	7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase; Code: H; COG: COG0801. (159 aa)
	nuoM	NADH dehydrogenase I chain M; Code: C; COG: COG1008. (509 aa)
	nuoL	NADH dehydrogenase I chain L; Code: CP; COG: COG1009. (613 aa)

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
hycE	nuoA	SDY_2918	SDY_2484	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.	0.579
hycE	nuoB	SDY_2918	SDY_2483	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.986
hycE	nuoC	SDY_2918	SDY_2482	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.	0.557
hycE	nuoE	SDY_2918	SDY_2481	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain E; Code: C; COG: COG1905.	0.737
hycE	nuoF	SDY_2918	SDY_2480	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.	0.680
hycE	nuoG	SDY_2918	SDY_2479	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.	0.715
hycE	nuoH	SDY_2918	SDY_2478	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.	0.819
hycE	nuoI	SDY_2918	SDY_2477	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.969
hycE	nuoJ	SDY_2918	SDY_2476	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.582
hycE	nuoK	SDY_2918	SDY_2475	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family.	0.698
hycE	nuoL	SDY_2918	SDY_2474	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain L; Code: CP; COG: COG1009.	0.852
hycE	nuoM	SDY_2918	SDY_2473	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain M; Code: C; COG: COG1008.	0.777
hycE	nuoN	SDY_2918	SDY_2472	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	NADH dehydrogenase I chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.	0.780
hycE	ydbK	SDY_2918	SDY_1461	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	Putative oxidoreductase, Fe-S subunit; Code: C; COG: COG0674.	0.973
hycE	yfhL	SDY_2918	SDY_2801	Large subunit of hydrogenase 3; Part of FHL complex; Code: C; COG: COG3261.	Conserved hypothetical protein; Code: C; COG: COG1145; orf.	0.958
hyfG	nuoA	SDY_2676	SDY_2484	Hydrogenase 4 subunit; Code: C; COG: COG3261.	NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family.	0.578
hyfG	nuoB	SDY_2676	SDY_2483	Hydrogenase 4 subunit; Code: C; COG: COG3261.	NADH dehydrogenase I chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.985
hyfG	nuoC	SDY_2676	SDY_2482	Hydrogenase 4 subunit; Code: C; COG: COG3261.	NADH dehydrogenase I chain C, D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.	0.558
hyfG	nuoE	SDY_2676	SDY_2481	Hydrogenase 4 subunit; Code: C; COG: COG3261.	NADH dehydrogenase I chain E; Code: C; COG: COG1905.	0.737
hyfG	nuoF	SDY_2676	SDY_2480	Hydrogenase 4 subunit; Code: C; COG: COG3261.	NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.	0.680