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| | phnN | ATP-binding component of phosphonate transport; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (185 aa) |
| | holA | DNA polymerase III, delta subunit; Code: L; COG: COG1466. (343 aa) |
| | ybeZ | Putative ATP-binding protein in pho regulon; Code: T; COG: COG1702. (359 aa) |
| | modF | ATP-binding component of molybdate transport system; Code: P; COG: COG1119. (490 aa) |
| | modC | ATP-binding component of molybdate transport; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa) |
| | SDY_0726 | Putative bacteriophage protein; Code: R; COG: COG1783. (272 aa) |
| | potG | ATP-binding component of putrescine transport system; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa) |
| | gsiA | Putative ATP-binding component of a transport system; Part of the ABC transporter complex GsiABCD involved in glutathione import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Glutathione importer (TC 3.A.1.5.11) family. (612 aa) |
| | ybiT | Putative ATP-binding component of a transport system; Code: R; COG: COG0488. (530 aa) |
| | glnQ | ATP-binding component of glutamine high-affinity transport system; Code: E; COG: COG1126. (240 aa) |
| | dinG | Probably ATP-dependent helicase; DNA-dependent ATPase and 5'-3' DNA helicase. (716 aa) |
| | rhlE | Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (454 aa) |
| | ybhF | Putative ATP-binding component of a transport system; Code: V; COG: COG1131. (583 aa) |
| | uvrB | Excision nuclease subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (673 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (225 aa) |
| | yojI | Putative ATP-binding component of a transport system; Code: QP; COG: COG4615. (547 aa) |
| | ccmA | ATP binding protein of heme exporter A; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (205 aa) |
| | yejH | Putative ATP-dependent helicase; Code: KL; COG: COG1061. (586 aa) |
| | yejF | Putative ATP-binding component of a transport system; Code: R; COG: COG4172; Belongs to the ABC transporter superfamily. (529 aa) |
| | yeiR | Conserved hypothetical protein; Code: R; COG: COG0523; orf. (328 aa) |
| | uup | Putative ATP-binding component of a transport system; Code: R; COG: COG0488. (635 aa) |
| | helD | DNA helicase IV; Code: L; COG: COG0210. (684 aa) |
| | yccC | Conserved hypothetical protein; Code: M; COG: COG3206; orf. (726 aa) |
| | iroC | Putative ABC transporter protein; Code: V; COG: COG1132. (1219 aa) |
| | yecC | Putative ATP-binding component of a transport system; Code: E; COG: COG1126. (250 aa) |
| | araG | ATP-binding component of high-affinity L-arabinose transport system; Part of the ABC transporter complex AraFGH involved in arabinose import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Arabinose importer (TC 3.A.1.2.2) family. (504 aa) |
| | yebM | Putative ATP-binding component of a transport system; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa) |
| | ruvB | Holliday junction helicase subunit A; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | minD | MinD; Cell division inhibitor, a membrane ATPase, activates minC; Code: D; COG: COG2894. (270 aa) |
| | SDY_1240 | Putative iron compound ABC transporter, ATP-binding protein; Code: PH; COG: COG1120. (252 aa) |
| | ychF | Putative GTP-binding protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | tdk | Thymidine kinase; Code: F; COG: COG1435. (205 aa) |
| | oppD | OppD; Similar to Salmonella ATP-binding protein of oligopeptide ABC transport system; Code: EP; COG: COG0444; Belongs to the ABC transporter superfamily. (337 aa) |
| | oppF | OppF; Similar to Salmonella ATP-binding protein of oligopeptide ABC transport system; Code: E; COG: COG4608; Belongs to the ABC transporter superfamily. (334 aa) |
| | btuR | cob(I)alamin adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa) |
| | sapF | Putative ATP-binding protein of peptide transport system; Code: V; COG: COG4167. (268 aa) |
| | sapD | Putative ATP-binding protein of peptide transport system; Code: V; COG: COG4170; Belongs to the ABC transporter superfamily. (330 aa) |
| | tyrR | TyrR; Transcriptional regulation of aroF, aroG, tyrA and aromatic amino acid transport; Code: KE; COG: COG3283. (513 aa) |
| | sitB | Iron transport protein, ATP-binding component; Code: P; COG: COG1121. (275 aa) |
| | SDY_1519 | Putative ATP-binding component of a transport system; Code: R; COG: COG4136. (217 aa) |
| | bioD-2 | Conserved hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (235 aa) |
| | SDY_1611 | Putative ATP-binding component of a transport system; Code: EP; COG: COG1124; Belongs to the ABC transporter superfamily. (308 aa) |
| | SDY_1712 | Putative enzyme; Code: KL; COG: COG1199. (636 aa) |
| | SDY_1733 | Putative ATP-binding component of a transport system; Code: E; COG: COG3842; Belongs to the ABC transporter superfamily. (337 aa) |
| | hrpA | Helicase, ATP-dependent; Code: L; COG: COG1643. (1281 aa) |
| | btuD | ATP-binding component of vitamin B12 transport system; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa) |
| | ynhD | Putative ATP-binding component of a transport system; Code: O; COG: COG0396. (248 aa) |
| | SDY_1922 | Hypothetical protein; Putative Fels-1 prophage DNA or RNA helicases of superfamily II. (220 aa) |
| | pspF | Psp operon transcriptional activator; Code: KT; COG: COG1221. (330 aa) |
| | potA | ATP-binding component of spermidine/putrescine transport; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | ycfV | Putative ATP-binding component of a transport system; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (228 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1148 aa) |
| | holB | DNA polymerase III, delta prime subunit; Code: L; COG: COG0470. (334 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | mrp | Putative ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (379 aa) |
| | udk | Uridine/cytidine kinase; Code: F; COG: COG0572. (231 aa) |
| | cobU | Cobinamide kinase/cobinamide phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (181 aa) |
| | ycbE | Putative ATP-binding component of a transport system; Code: P; COG: COG1116. (172 aa) |
| | mukB | Kinesin-like cell division protein involved in chromosome partitioning; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1483 aa) |
| | ycaH | YcaH; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (328 aa) |
| | msbA | ATP-binding transport protein; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | cmk | Cytidylate kinase; Code: F; COG: COG0283. (227 aa) |
| | ycaJ | Putative polynucleotide enzyme; Code: L; COG: COG2256. (447 aa) |
| | ftsK | Cell division protein; Code: D; COG: COG1674. (1368 aa) |
| | cydD | ATP-binding component of cytochrome-related transport, Zn sensitive; Code: CO; COG: COG4988. (588 aa) |
| | cydC | ATP-binding component of cytochrome-related transport; Code: CO; COG: COG4987. (573 aa) |
| | clpA | ATP-binding component of serine protease; Code: O; COG: COG0542; Belongs to the ClpA/ClpB family. (758 aa) |
| | ybjZ | Putative ATP-binding component of a transport system; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (650 aa) |
| | ybjD | Conserved hypothetical protein; Code: L; COG: COG3593; orf. (552 aa) |
| | artP | ATP-binding component of 3rd arginine transport system; Code: E; COG: COG4161. (242 aa) |
| | pta | Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | hisP | ATP-binding component of histidine transport; Code: E; COG: COG4598. (257 aa) |
| | cysA | ATP-binding component of sulfate permease A protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa) |
| | ypfI | Conserved hypothetical protein; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (671 aa) |
| | hda | Putative DNA replication factor; Mediates the interaction of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinitiation, a process called regulatory inhibition of DnaA or RIDA (By similarity); Belongs to the DnaA family. HdA subfamily. (248 aa) |
| | der | Putative GTP-binding factor; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (503 aa) |
| | yfhA | Putative 2-component transcriptional regulator; Code: T; COG: COG2204. (444 aa) |
| | ffh | GTP-binding export factor; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belong [...] (453 aa) |
| | recN | Protein used in recombination and DNA repair; May be involved in recombinational repair of damaged DNA. (553 aa) |
| | SDY_2798 | Hypothetical bacteriophage protein; Code: KL; COG: COG0553. (311 aa) |
| | era | GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (301 aa) |
| | lepA | GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | srmB | ATP-dependent RNA helicase; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (444 aa) |
| | clpB | Heat shock protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (857 aa) |
| | proV | ATP-binding component of transport system for glycine, betaine and proline; Code: E; COG: COG4175. (341 aa) |
| | SDY_2883 | Conserved hypothetical protein; Code: J; COG: COG0617; orf. (347 aa) |
| | recA | DNA-dependent ATPase, DNA- and ATP-dependent coprotease; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) |
| | ygaA | Putative 2-component transcriptional regulator; Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54. (529 aa) |
| | hypB | Guanine-nucleotide binding protein; Functions as nickel donor for large subunit of hydrogenase 3; Code: OK; COG: COG0378. (290 aa) |
| | mutS | Methyl-directed mismatch repair; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cysN | ATP-sulfurylase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | recD | ATP-dependent dsDNA/ssDNA exonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombina [...] (608 aa) |
| | recB | ATP-dependent dsDNA/ssDNA exonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombina [...] (1180 aa) |
| | recC | ATP-dependent dsDNA/ssDNA exonuclease V subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombina [...] (1122 aa) |
| | yghT | Conserved hypothetical protein. (234 aa) |
| | gspE | Putative type II secretion protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (497 aa) |
| | yggR | Putative protein transport; Code: NU; COG: COG2805. (341 aa) |
| | yggC | Putative kinase; Code: H; COG: COG1072. (237 aa) |
| | SDY_3149 | Putative ATP-binding protein of ABC transport system; Code: P; COG: COG1118. (225 aa) |
| | SDY_3150 | Hypothetical protein. (91 aa) |
| | SDY_3151 | Putative ATP-binding protein of ABC transport system; Code: P; COG: COG1122. (130 aa) |
| | ygfD | Putative nucleotide-binding protein; Code: E; COG: COG1703. (306 aa) |
| | deaD | Inducible ATP-independent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (646 aa) |
| | infB | Protein chain initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (890 aa) |
| | hflB | HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (644 aa) |
| | yhbZ | Putative GTP-binding factor; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa) |
| | yrbF | Putative ATP-binding component of a transport system; Code: Q; COG: COG1127. (269 aa) |
| | yhbG | Putative ATP-binding component of a transport system; Code: R; COG: COG1137. (241 aa) |
| | yhbJ | Conserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa) |
| | yhcM | Conserved hypothetical protein; Reduces the stability of FtsZ polymers in the presence of ATP. (375 aa) |
| | tufA | Protein chain elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | fusA | GTP-binding protein chain elongation factor EF-G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase fa [...] (704 aa) |
| | yheS | Putative ATP-binding component of a transport system; Code: R; COG: COG0488. (637 aa) |
| | shuV | Putative ATP-binding component of hemin transport system; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. (256 aa) |
| | SDY_3586 | Hypothetical protein; Code: L; COG: COG0514; orf. (385 aa) |
| | gntK | Gluconokinase 2, thermoresistant; Code: G; COG: COG3265. (162 aa) |
| | livF | ATP-binding component of leucine transport; Code: E; COG: COG0410; Belongs to the ABC transporter superfamily. (241 aa) |
| | livG | ATP-binding component of high-affinity branched-chain amino acid transport system; Code: E; COG: COG0411. (255 aa) |
| | ftsE | ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division. (222 aa) |
| | ftsY | Cell division membrane protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (498 aa) |
| | nikD | ATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa) |
| | nikE | ATP-binding protein of nickel transport system; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa) |
| | malT | Positive regulator of mal regulon; Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto- oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box. (899 aa) |
| | feoB | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (773 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | hydG | Sensor HydH response regulator of hydrogenase 3 activity; Code: T; COG: COG2204. (441 aa) |
| | coaA | Pantothenate kinase; Code: H; COG: COG1072. (316 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | hslU | Heat shock protein hslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa) |
| | yihK | Putative GTP-binding factor; Code: T; COG: COG1217. (607 aa) |
| | glnG | Response regulator for gln; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa) |
| | yihA | Conserved hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (199 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B; Code: H; COG: COG1763. (170 aa) |
| | recQ | ATP-dependent DNA helicase; Code: L; COG: COG0514. (611 aa) |
| | uvrD | DNA-dependent ATPase I and helicase II; Code: L; COG: COG0210. (720 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | rhlB | Putative ATP-dependent RNA helicase; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. Belongs to the DEAD box helicase family. RhlB subfamily. (421 aa) |
| | rep | Rep helicase; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa) |
| | yieN | Putative 2-component regulator; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (506 aa) |
| | atpA | Membrane-bound ATP synthase, F1 sector, alpha-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (513 aa) |
| | atpD | Membrane-bound ATP synthase, F1 sector, beta-subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (460 aa) |
| | pstB | ATP-binding component of high-affinity phosphate-specific transport system; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (257 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | recG | DNA helicase; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (693 aa) |
| | phnC | ATP-binding component of phosphonate transport; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (262 aa) |
| | phnK | ATP-binding component of phosphonate transport; Code: P; COG: COG4107. (252 aa) |
| | phnL | ATP-binding component of phosphonate transport; Code: P; COG: COG4778. (226 aa) |
| | fepC | ATP-binding component of ferric enterobactin transport; Code: PH; COG: COG1120. (271 aa) |
| | rbsA | Putative ATP-binding protein of ribose ABC transport system; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (495 aa) |
| | recF | ssDNA and dsDNA binding, ATP binding; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (357 aa) |
| | dnaA | DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (467 aa) |
| | thdF | GTP-binding protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | selB | selenocysteinyl-tRNA-specific translation factor; Code: J; COG: COG3276. (614 aa) |
| | ytfR | Putative ATP-binding component of a transport system; Code: G; COG: COG1129. (500 aa) |
| | yjgR | Conserved hypothetical protein; Code: R; COG: COG0433; orf. (500 aa) |
| | fecE | ATP-binding component of citrate-dependent iron(III) transport protein; Code: PH; COG: COG1120. (255 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | hflX | GTP-binding subunit of protease specific for phage lambda cII repressor; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa) |
| | miaA | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | yjeE | Conserved hypothetical protein; Code: R; COG: COG0802; orf. (153 aa) |
| | yjeQ | Conserved hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (337 aa) |
| | uvrA | Excision nuclease subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (471 aa) |
| | dppF | Putative ATP-binding component of dipeptide transport system; Code: E; COG: COG4608; Belongs to the ABC transporter superfamily. (334 aa) |
| | dppD | Putative ATP-binding component of dipeptide transport system; Code: EP; COG: COG0444; Belongs to the ABC transporter superfamily. (327 aa) |
| | yjiA | Conserved hypothetical protein; Code: R; COG: COG0523; orf. (284 aa) |
| | dnaC | Chromosome replication; Initiation and chain elongation; Code: L; COG: COG1484. (245 aa) |
| | prfC | Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | sms | Probable ATP-dependent protease; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa) |
| | nadR | Probable nadAB transcriptional regulator; Code: H; COG: COG3172. (417 aa) |
| | yjjK | Putative ATP-binding component of a transport system; Code: R; COG: COG0488. (555 aa) |
| | ybbL | Putative ATP-binding component of a transport system; Code: R; COG: COG4619. (225 aa) |
| | SDY_0417 | Putative cytoplasmic membrane export protein; Code: V; COG: COG2274. (508 aa) |
| | adk | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | dnaX | DNA polymerase III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (643 aa) |
| | tauB | Taurine ATP-binding component of a transport system; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa) |
| | yadG | Putative ATP-binding component of a transport system; Code: V; COG: COG1131. (308 aa) |
| | hepA | Probable ATP-dependent RNA helicase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | yabJ | Putative ATP-binding component of a transport system; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa) |
| | secA | Preprotein translocase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa) |
| | yacE | Putative DNA repair protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | hofB | HofB; Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake; Code: NU; COG: COG2804. (444 aa) |
| | fhuC | ATP-binding component of hydroxymate-dependent iron transport; Code: PH; COG: COG1120. (265 aa) |
| | abc | ATP-binding component of a transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | lon | DNA-binding, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overpr [...] (812 aa) |
| | clpX | ATP-dependent specificity component of clpP serine protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (424 aa) |
| | sbcC | ATP-dependent dsDNA exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SMC family. SbcC subfamily. (1045 aa) |
| | aroL | Shikimate kinase II; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. (174 aa) |
| | mdlA | ATP-binding component of a transport system; Code: V; COG: COG1132. (590 aa) |
| | mdlB | Putative ATP-binding component of a transport system; Code: V; COG: COG1132. (593 aa) |
| | ybbA | Putative ATP-binding component of a transport system; Code: Q; COG: COG4181. (228 aa) |
