STRINGSTRING
evgS evgS evgA evgA mgtA mgtA cyaA cyaA yrbL yrbL phoQ phoQ phoP phoP mgrB mgrB slyB slyB rstA rstA nagA nagA lacZ lacZ hemL hemL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
evgSPutative sensor for regulator EvgA; Code: ET; COG: COG0834. (1197 aa)
evgAPutative positive transcription regulator; Sensor EvgS; Code: TK; COG: COG2197. (204 aa)
mgtAMg2+ transport ATPase, P-type 1; Code: P; COG: COG0474. (898 aa)
cyaAAdenylate cyclase; Code: F; COG: COG3072; Belongs to the adenylyl cyclase class-1 family. (848 aa)
yrbLConserved hypothetical protein. (210 aa)
phoQSensor protein PhoQ; Code: T; COG: COG0642. (486 aa)
phoPTranscriptional regulatory protein; Code: TK; COG: COG0745. (223 aa)
mgrBConserved hypothetical protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. (47 aa)
slyBPutative outer membrane protein; Code: M; COG: COG3133. (155 aa)
rstAResponse transcriptional regulatory protein; RstB sensor; Code: TK; COG: COG0745. (238 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Code: G; COG: COG1820. (382 aa)
lacZbeta-D-galactosidase; Code: G; COG: COG3250; Belongs to the glycosyl hydrolase 2 family. (969 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Aminomutase; Code: H; COG: COG0001. (426 aa)
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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