STRINGSTRING
ompR ompR hfq hfq rnhA rnhA lacZ lacZ ompC ompC ompA ompA manX manX phoP phoP rne rne ompF ompF fadL fadL rnc rnc rpoS rpoS relA relA pnp pnp crp crp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ompRResponse regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745. (239 aa)
hfqHost factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (102 aa)
rnhARNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (155 aa)
lacZbeta-D-galactosidase; Code: G; COG: COG3250; Belongs to the glycosyl hydrolase 2 family. (969 aa)
ompCOuter membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family. (375 aa)
ompAOuter membrane protein 3a; II*;G;d; Code: M; COG: COG2885; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (350 aa)
manXPTS enzyme IIAB, mannose-specific; Code: G; COG: COG2893. (323 aa)
phoPTranscriptional regulatory protein; Code: TK; COG: COG0745. (223 aa)
rneRNase E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (1061 aa)
ompFOuter membrane protein 1a (Ia;b;F); Code: M; COG: COG3203; Belongs to the Gram-negative porin family. (362 aa)
fadLFadL; Transport of long-chain fatty acids; sensitivity to phage T2; Code: I; COG: COG2067. (448 aa)
rncRNase III, ds RNA; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (226 aa)
rpoSRNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (330 aa)
relA(p)ppGpp synthetase I; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (744 aa)
pnpPolynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (734 aa)
crpCyclic AMP receptor protein; Code: T; COG: COG0664. (210 aa)
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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