7 items (Shigella dysenteriae) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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proteins of unknown 3D structure

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Your Input:
	csrA	Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa)
	slyA	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (146 aa)
	phoP	Transcriptional regulatory protein; Code: TK; COG: COG0745. (223 aa)
	phoQ	Sensor protein PhoQ; Code: T; COG: COG0642. (486 aa)
	argT	Lysine-, arginine-, ornithine-binding periplasmic protein; Code: ET; COG: COG0834; Belongs to the bacterial solute-binding protein 3 family. (260 aa)
	rpoS	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (330 aa)
	ompR	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745. (239 aa)

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
csrA	phoP	SDY_2892	SDY_2022	Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).	Transcriptional regulatory protein; Code: TK; COG: COG0745.	0.408
csrA	rpoS	SDY_2892	SDY_2940	Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.592
ompR	phoQ	SDY_3671	SDY_2023	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	Sensor protein PhoQ; Code: T; COG: COG0642.	0.858
ompR	rpoS	SDY_3671	SDY_2940	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.677
ompR	slyA	SDY_3671	SDY_1865	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	0.457
phoP	csrA	SDY_2022	SDY_2892	Transcriptional regulatory protein; Code: TK; COG: COG0745.	Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).	0.408
phoP	phoQ	SDY_2022	SDY_2023	Transcriptional regulatory protein; Code: TK; COG: COG0745.	Sensor protein PhoQ; Code: T; COG: COG0642.	0.999
phoP	rpoS	SDY_2022	SDY_2940	Transcriptional regulatory protein; Code: TK; COG: COG0745.	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.803
phoP	slyA	SDY_2022	SDY_1865	Transcriptional regulatory protein; Code: TK; COG: COG0745.	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	0.682
phoQ	ompR	SDY_2023	SDY_3671	Sensor protein PhoQ; Code: T; COG: COG0642.	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	0.858
phoQ	phoP	SDY_2023	SDY_2022	Sensor protein PhoQ; Code: T; COG: COG0642.	Transcriptional regulatory protein; Code: TK; COG: COG0745.	0.999
phoQ	rpoS	SDY_2023	SDY_2940	Sensor protein PhoQ; Code: T; COG: COG0642.	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	0.616
phoQ	slyA	SDY_2023	SDY_1865	Sensor protein PhoQ; Code: T; COG: COG0642.	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	0.492
rpoS	csrA	SDY_2940	SDY_2892	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).	0.592
rpoS	ompR	SDY_2940	SDY_3671	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	0.677
rpoS	phoP	SDY_2940	SDY_2022	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	Transcriptional regulatory protein; Code: TK; COG: COG0745.	0.803
rpoS	phoQ	SDY_2940	SDY_2023	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	Sensor protein PhoQ; Code: T; COG: COG0642.	0.616
rpoS	slyA	SDY_2940	SDY_1865	RNA polymerase, sigma S factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response.	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	0.514
slyA	ompR	SDY_1865	SDY_3671	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	0.457
slyA	phoP	SDY_1865	SDY_2022	Transcriptional regulator for cryptic hemolysin; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family.	Transcriptional regulatory protein; Code: TK; COG: COG0745.	0.682