node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arcB | dnaK | SDY_3391 | SDY_0013 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.435 |
arcB | hpt | SDY_3391 | SDY_0034 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | Hypoxanthine phosphoribosyltransferase; Code: F; COG: COG0634; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.682 |
arcB | mopA | SDY_3391 | SDY_4449 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.453 |
arcB | phoB | SDY_3391 | SDY_0338 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | Positive response regulator for pho regulon; Sensor is PhoR (or CreC); Code: TK; COG: COG0745. | 0.976 |
arcB | phoP | SDY_3391 | SDY_2022 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | Transcriptional regulatory protein; Code: TK; COG: COG0745. | 0.972 |
arcB | phoQ | SDY_3391 | SDY_2023 | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | Sensor protein PhoQ; Code: T; COG: COG0642. | 0.936 |
clpP | dnaJ | SDY_0295 | SDY_0014 | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.695 |
clpP | dnaK | SDY_0295 | SDY_0013 | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.755 |
clpP | mopA | SDY_0295 | SDY_4449 | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.826 |
clpP | mopB | SDY_0295 | SDY_4448 | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.783 |
clpP | rpoH | SDY_0295 | SDY_3612 | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | RNA polymerase, sigma(32) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.523 |
dnaJ | clpP | SDY_0014 | SDY_0295 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.695 |
dnaJ | dnaK | SDY_0014 | SDY_0013 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
dnaJ | mopA | SDY_0014 | SDY_4449 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.934 |
dnaJ | mopB | SDY_0014 | SDY_4448 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.866 |
dnaJ | rpoH | SDY_0014 | SDY_3612 | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | RNA polymerase, sigma(32) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.760 |
dnaK | arcB | SDY_0013 | SDY_3391 | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Aerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. | 0.435 |
dnaK | clpP | SDY_0013 | SDY_0295 | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | ATP-dependent proteolytic subunit of clpA-clpP serine protease; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.755 |
dnaK | dnaJ | SDY_0013 | SDY_0014 | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | Heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...] | 0.999 |
dnaK | mopA | SDY_0013 | SDY_4449 | Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. | GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.984 |