STRINGSTRING
gspK gspK gspM gspM tolC tolC gntR gntR ompR ompR talC talC hfq hfq gspE gspE csrA csrA phoQ phoQ phoP phoP phoB phoB lon lon gspC gspC gspF gspF gspG gspG gspI gspI gspJ gspJ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gspKPutative type II secretion protein; Code: U; COG: COG3156. (325 aa)
gspMPutative secretion pathway protein; Code: U; COG: COG3149. (140 aa)
tolCOuter membrane channel; Specific tolerance to colicin E1; segregation of daughter chromosomes; Code: MU; COG: COG1538. (495 aa)
gntRRegulator of gnt operon; Code: K; COG: COG1609. (312 aa)
ompRResponse regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745. (239 aa)
talCPutative transaldolase; Catalyzes the reversible formation of fructose 6-phosphate from dihydroxyacetone and D-glyceraldehyde 3-phosphate via an aldolization reaction; Belongs to the transaldolase family. Type 3A subfamily. (220 aa)
hfqHost factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (102 aa)
gspEPutative type II secretion protein; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins. (497 aa)
csrACarbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (61 aa)
phoQSensor protein PhoQ; Code: T; COG: COG0642. (486 aa)
phoPTranscriptional regulatory protein; Code: TK; COG: COG0745. (223 aa)
phoBPositive response regulator for pho regulon; Sensor is PhoR (or CreC); Code: TK; COG: COG0745. (229 aa)
lonDNA-binding, ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. Endogenous substrates include the regulatory proteins RcsA and SulA, the transcriptional activator SoxS, and UmuD. Its overpr [...] (812 aa)
gspCPutative general secretion protein GspC; Code: U; COG: COG3031. (276 aa)
gspFPutative type II secretion protein; Code: NU; COG: COG1459. (399 aa)
gspGPutative type II secretion protein; Code: NU; COG: COG2165. (151 aa)
gspIPutative type II secretion protein; Code: NU; COG: COG2165. (123 aa)
gspJPutative type II secretion protein; Code: U; COG: COG4795. (189 aa)
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
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