4 items (Shigella dysenteriae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dnaK	Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family. (638 aa)
	envZ	Protein histidine kinase/phosphatase sensor for OmpR; Modulates expression of ompF and ompC; Code: T; COG: COG0642. (450 aa)
	ompR	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745. (239 aa)
	ompC	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family. (375 aa)

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
envZ	ompC	SDY_3672	SDY_0861	Protein histidine kinase/phosphatase sensor for OmpR; Modulates expression of ompF and ompC; Code: T; COG: COG0642.	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	0.731
envZ	ompR	SDY_3672	SDY_3671	Protein histidine kinase/phosphatase sensor for OmpR; Modulates expression of ompF and ompC; Code: T; COG: COG0642.	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	0.999
ompC	envZ	SDY_0861	SDY_3672	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	Protein histidine kinase/phosphatase sensor for OmpR; Modulates expression of ompF and ompC; Code: T; COG: COG0642.	0.731
ompC	ompR	SDY_0861	SDY_3671	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	0.736
ompR	envZ	SDY_3671	SDY_3672	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	Protein histidine kinase/phosphatase sensor for OmpR; Modulates expression of ompF and ompC; Code: T; COG: COG0642.	0.999
ompR	ompC	SDY_3671	SDY_0861	Response regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745.	Outer membrane protein 1b; Ib;c; Code: M; COG: COG3203; Belongs to the Gram-negative porin family.	0.736