18 items (Shigella dysenteriae) - STRING interaction network

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	dapA	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
	deoD	Purine-nucleoside phosphorylase; Code: F; COG: COG0813. (239 aa)
	nrdG	Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)
	dnaA	DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (467 aa)
	glpK	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (502 aa)
	glpD	Sn-glycerol-3-phosphate dehydrogenase (aerobic); Code: C; COG: COG0578; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (501 aa)
	ftsE	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division. (222 aa)
	ftsX	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (352 aa)
	hflB	HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (644 aa)
	glpA	Sn-glycerol-3-phosphate dehydrogenase (anaerobic), large subunit; Code: C; COG: COG0578; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (542 aa)
	ptsI	PEP-protein phosphotransferase system enzyme I; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
	gnd	Gluconate-6-phosphate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
	adhP	Alcohol dehydrogenase; Code: R; COG: COG1064. (375 aa)
	adhE	Aldehyde-alcohol dehydrogenase; Code: C; COG: COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa)
	galE	UDP-galactose-4-epimerase; Code: M; COG: COG1087; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
	mrcB	Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (844 aa)
	ftsZ	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (383 aa)
	ftsA	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (420 aa)

Your Current Organism:

Shigella dysenteriae

NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
adhE	adhP	SDY_1295	SDY_1608	Aldehyde-alcohol dehydrogenase; Code: C; COG: COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Alcohol dehydrogenase; Code: R; COG: COG1064.	0.968
adhE	glpK	SDY_1295	SDY_3818	Aldehyde-alcohol dehydrogenase; Code: C; COG: COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.	0.440
adhP	adhE	SDY_1608	SDY_1295	Alcohol dehydrogenase; Code: R; COG: COG1064.	Aldehyde-alcohol dehydrogenase; Code: C; COG: COG1454; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.	0.968
ftsA	ftsE	SDY_0124	SDY_3614	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	0.637
ftsA	ftsX	SDY_0124	SDY_3613	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	0.618
ftsA	ftsZ	SDY_0124	SDY_0125	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	0.999
ftsA	mrcB	SDY_0124	SDY_0165	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.522
ftsE	ftsA	SDY_3614	SDY_0124	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	0.637
ftsE	ftsX	SDY_3614	SDY_3613	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	0.998
ftsE	ftsZ	SDY_3614	SDY_0125	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	0.692
ftsE	mrcB	SDY_3614	SDY_0165	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.418
ftsX	ftsA	SDY_3613	SDY_0124	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	0.618
ftsX	ftsE	SDY_3613	SDY_3614	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	0.998
ftsX	ftsZ	SDY_3613	SDY_0125	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	0.449
ftsX	mrcB	SDY_3613	SDY_0165	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.544
ftsZ	ftsA	SDY_0125	SDY_0124	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	ATP-binding cell division protein; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	0.999
ftsZ	ftsE	SDY_0125	SDY_3614	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	ATP-binding component of a membrane-associated complex involved in cell division; Part of the ABC transporter FtsEX involved in cellular division.	0.692
ftsZ	ftsX	SDY_0125	SDY_3613	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	Cell division membrane protein; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.	0.449
ftsZ	hflB	SDY_0125	SDY_3359	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.421
ftsZ	mrcB	SDY_0125	SDY_0165	Tubulin-like GTP-binding protein and GTPase; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	Peptidoglycan synthetase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.660