STRINGSTRING
creB creB evgS evgS evgA evgA yjdG yjdG uhpA uhpA SDY_4134 SDY_4134 SDY_4127 SDY_4127 glnG glnG cpxR cpxR hydG hydG ompR ompR arcB arcB ygiX ygiX barA barA yfhA yfhA baeR baeR yehT yehT phoP phoP rstA rstA hnr hnr narL narL uvrY uvrY yedW yedW torR torR narP narP rcsB rcsB phoB phoB SDY_0506 SDY_0506 kdpE kdpE rcsC rcsC arcA arcA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
creBCatabolic regulation response regulator; Code: TK; COG: COG0745. (229 aa)
evgSPutative sensor for regulator EvgA; Code: ET; COG: COG0834. (1197 aa)
evgAPutative positive transcription regulator; Sensor EvgS; Code: TK; COG: COG2197. (204 aa)
yjdGPutative 2-component transcriptional regulator; Code: KT; COG: COG4565. (239 aa)
uhpAResponse regulator, positive activator of uhpT transcription; Sensor, uhpB; Code: TK; COG: COG2197. (196 aa)
SDY_4134Putative transcriptional regulator; Code: TK; COG: COG0745. (241 aa)
SDY_4127Putative histidine kinase; Code: T; COG: COG0642. (754 aa)
glnGResponse regulator for gln; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
cpxRTranscriptional regulator in 2-component system; Code: TK; COG: COG0745. (232 aa)
hydGSensor HydH response regulator of hydrogenase 3 activity; Code: T; COG: COG2204. (441 aa)
ompRResponse regulator affecting transcription of ompC and ompF; Sensor, EnvZ; outer membrane protein synthesis; Code: TK; COG: COG0745. (239 aa)
arcBAerobic respiration sensor-response protein; Histidine protein kinase/phosphatase, sensor for arcA; Code: T; COG: COG0642. (778 aa)
ygiXPutative 2-component transcriptional regulator; Code: TK; COG: COG0745. (219 aa)
barASensor-regulator; Activates OmpR by phophorylation; Code: T; COG: COG0642. (918 aa)
yfhAPutative 2-component transcriptional regulator; Code: T; COG: COG2204. (444 aa)
baeRTranscriptional response regulatory protein; Sensor BaeS; Code: TK; COG: COG0745. (240 aa)
yehTConserved hypothetical protein; Code: KT; COG: COG3279; orf. (244 aa)
phoPTranscriptional regulatory protein; Code: TK; COG: COG0745. (223 aa)
rstAResponse transcriptional regulatory protein; RstB sensor; Code: TK; COG: COG0745. (238 aa)
hnrHnr protein; Regulates the turnover of the sigma S factor (RpoS) by promoting its proteolysis in exponentially growing cells. Acts by binding and delivering RpoS to the ClpXP protease. RssB is not co- degraded with RpoS, but is released from the complex and can initiate a new cycle of RpoS recognition and degradation. (337 aa)
narLNarL; Pleiotrophic regulation of anaerobic respiration: response regulator for nar, frd, dms and tor genes; Code: TK; COG: COG2197. (216 aa)
uvrYPutative 2-component transcriptional regulator; Code: TK; COG: COG2197. (218 aa)
yedWPutative 2-component transcriptional regulator; Code: TK; COG: COG0745. (232 aa)
torRResponse transcriptional regulator for torA; Sensor TorS; Code: TK; COG: COG0745. (230 aa)
narPNitrate/nitrite response regulator; Sensor NarQ; Code: TK; COG: COG2197. (215 aa)
rcsBPositive response regulator for colanic capsule biosynthesis; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa)
phoBPositive response regulator for pho regulon; Sensor is PhoR (or CreC); Code: TK; COG: COG0745. (229 aa)
SDY_0506Putative response regulator; Hexosephosphate transport; Code: TK; COG: COG2197. (209 aa)
kdpERegulator of kdp operon; Transcriptional effector; Code: TK; COG: COG0745. (225 aa)
rcsCSensor for ctr capsule biosynthesis; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (933 aa)
arcANegative response regulator of genes in aerobic pathways; Sensors, ArcB and CpxA; Code: TK; COG: COG0745. (238 aa)
Your Current Organism:
Shigella dysenteriae
NCBI taxonomy Id: 300267
Other names: S. dysenteriae Sd197, Shigella dysenteriae Sd197, Shigella dysenteriae str. Sd197, Shigella dysenteriae strain Sd197
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.