(7 nodes) U1 snRNA binding network (Anopheles merus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182UXM8	MPN domain-containing protein. (2388 aa)
	A0A182UTB9	U1 small nuclear ribonucleoprotein A. (216 aa)
	A0A182V6W7	U1 small nuclear ribonucleoprotein 70K. (438 aa)
	A0A182VCP6	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family. (152 aa)
	A0A182VEK9	RRM domain-containing protein. (303 aa)
	A0A182VK45	Snurportin1 domain-containing protein. (380 aa)
	A0A182VLJ7	Importin N-terminal domain-containing protein. (983 aa)

Your Current Organism:

Anopheles merus

NCBI taxonomy Id: 30066
Other names: A. merus

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A182UTB9	A0A182UXM8	U1 small nuclear ribonucleoprotein A.	MPN domain-containing protein.	0.940
A0A182UTB9	A0A182V6W7	U1 small nuclear ribonucleoprotein A.	U1 small nuclear ribonucleoprotein 70K.	0.971
A0A182UTB9	A0A182VCP6	U1 small nuclear ribonucleoprotein A.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.993
A0A182UTB9	A0A182VK45	U1 small nuclear ribonucleoprotein A.	Snurportin1 domain-containing protein.	0.502
A0A182UXM8	A0A182UTB9	MPN domain-containing protein.	U1 small nuclear ribonucleoprotein A.	0.940
A0A182UXM8	A0A182V6W7	MPN domain-containing protein.	U1 small nuclear ribonucleoprotein 70K.	0.841
A0A182UXM8	A0A182VCP6	MPN domain-containing protein.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.828
A0A182V6W7	A0A182UTB9	U1 small nuclear ribonucleoprotein 70K.	U1 small nuclear ribonucleoprotein A.	0.971
A0A182V6W7	A0A182UXM8	U1 small nuclear ribonucleoprotein 70K.	MPN domain-containing protein.	0.841
A0A182V6W7	A0A182VCP6	U1 small nuclear ribonucleoprotein 70K.	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	0.974
A0A182V6W7	A0A182VEK9	U1 small nuclear ribonucleoprotein 70K.	RRM domain-containing protein.	0.602
A0A182VCP6	A0A182UTB9	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	U1 small nuclear ribonucleoprotein A.	0.993
A0A182VCP6	A0A182UXM8	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	MPN domain-containing protein.	0.828
A0A182VCP6	A0A182V6W7	U1 small nuclear ribonucleoprotein C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA; Belongs to the U1 small nuclear ribonucleoprotein C family.	U1 small nuclear ribonucleoprotein 70K.	0.974
A0A182VEK9	A0A182V6W7	RRM domain-containing protein.	U1 small nuclear ribonucleoprotein 70K.	0.602
A0A182VK45	A0A182UTB9	Snurportin1 domain-containing protein.	U1 small nuclear ribonucleoprotein A.	0.502