(71 nodes) Inositol phosphate metabolism network (Anopheles merus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182V4Y5	Myotubularin phosphatase domain-containing protein. (701 aa)
	Tpi	Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (206 aa)
	A0A3F2Z0E3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1431 aa)
	A0A3F2Z0D3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1425 aa)
	A0A3F2Z0C3	PI3K/PI4K domain-containing protein. (594 aa)
	A0A3F2Z0B8	PI3K/PI4K domain-containing protein. (566 aa)
	A0A2Y9D321	SAC domain-containing protein. (857 aa)
	A0A1Y9IRX2	Uncharacterized protein. (327 aa)
	A0A1I8JVH6	Kinase; Belongs to the inositol phosphokinase (IPK) family. (432 aa)
	A0A1I8JVE5	Kinase; Belongs to the inositol phosphokinase (IPK) family. (329 aa)
	A0A182VPA9	Uncharacterized protein. (298 aa)
	A0A182VP24	SH2 domain-containing protein. (786 aa)
	A0A182VNX0	Uncharacterized protein. (197 aa)
	A0A182VNS5	RRM domain-containing protein. (164 aa)
	A0A182VNQ2	Uncharacterized protein. (871 aa)
	A0A182VNI1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1099 aa)
	A0A182VM12	Uncharacterized protein. (336 aa)
	A0A182VLZ0	Homeobox domain-containing protein. (175 aa)
	A0A182VLE6	Inositol-1-monophosphatase. (274 aa)
	A0A182VL56	Uncharacterized protein. (715 aa)
	A0A182VKE3	Phosphoinositide phospholipase C. (2200 aa)
	A0A182VIN9	Uncharacterized protein. (904 aa)
	A0A182VIK2	PLCXc domain-containing protein. (329 aa)
	A0A182VH99	GFO_IDH_MocA domain-containing protein. (420 aa)
	A0A182VG99	Kinase; Belongs to the inositol phosphokinase (IPK) family. (328 aa)
	A0A182VG96	PIPK domain-containing protein. (1083 aa)
	A0A182VF99	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1224 aa)
	A0A182VF33	Inos-1-P_synth domain-containing protein. (557 aa)
	A0A182VED5	Uncharacterized protein. (306 aa)
	A0A182VDU3	Uncharacterized protein. (1982 aa)
	A0A182VCV1	IPPc domain-containing protein. (510 aa)
	A0A182VBA3	Myotubularin phosphatase domain-containing protein. (599 aa)
	A0A182VA95	Aldedh domain-containing protein. (521 aa)
	A0A182V9M1	Myotubularin phosphatase domain-containing protein. (876 aa)
	A0A182V996	Uncharacterized protein. (403 aa)
	A0A182V8M4	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (487 aa)
	A0A182V8I1	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (1780 aa)
	A0A182V8E4	IPPc domain-containing protein. (642 aa)
	A0A182V7C6	Uncharacterized protein. (1879 aa)
	A0A182V7A7	CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (227 aa)
	A0A182V5Y0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1035 aa)
	A0A182V5R9	SAM domain-containing protein. (139 aa)
	A0A182V420	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1989 aa)
	A0A182V2X5	Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (537 aa)
	A0A182V2T7	Uncharacterized protein. (354 aa)
	A0A182V2D1	Rho-GAP domain-containing protein. (884 aa)
	A0A182V287	Uncharacterized protein. (555 aa)
	A0A182V1P2	C2 NT-type domain-containing protein. (1131 aa)
	A0A182V1B6	Uncharacterized protein. (461 aa)
	A0A182V0X7	Uncharacterized protein. (1054 aa)
	A0A182V0R0	Uncharacterized protein; Belongs to the histidine acid phosphatase family. (295 aa)
	A0A182V029	Uncharacterized protein. (976 aa)
	A0A182UYM1	Uncharacterized protein. (644 aa)
	A0A182UXW4	Uncharacterized protein. (292 aa)
	A0A182UX43	Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
	A0A182UWT6	Uncharacterized protein. (205 aa)
	A0A182UVH5	Uncharacterized protein. (515 aa)
	A0A182UTV6	Uncharacterized protein. (797 aa)
	A0A182UTK0	Triosephosphate isomerase. (247 aa)
	A0A182UTG2	Homeobox domain-containing protein. (108 aa)
	A0A182USK0	Inositol-1-monophosphatase. (280 aa)
	A0A182UQN4	Uncharacterized protein. (1152 aa)
	A0A182UQI8	DUF1298 domain-containing protein. (444 aa)
	A0A182UQG3	PH domain-containing protein. (1403 aa)
	A0A182UQ89	Kinase; Belongs to the inositol phosphokinase (IPK) family. (675 aa)
	A0A182UPW4	TPR_REGION domain-containing protein. (217 aa)
	A0A182UP87	Uncharacterized protein. (755 aa)
	A0A182UP61	Uncharacterized protein. (578 aa)
	A0A182UNQ3	Uncharacterized protein. (70 aa)
	A0A182UM17	Uncharacterized protein. (2203 aa)
	A0A182UM08	SAC domain-containing protein. (596 aa)

Your Current Organism:

Anopheles merus

NCBI taxonomy Id: 30066
Other names: A. merus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182UM08	A0A182UNQ3	A0A182UM08	A0A182UNQ3	SAC domain-containing protein.	Uncharacterized protein.	0.645
A0A182UM08	A0A182UP61	A0A182UM08	A0A182UP61	SAC domain-containing protein.	Uncharacterized protein.	0.880
A0A182UM08	A0A182UP87	A0A182UM08	A0A182UP87	SAC domain-containing protein.	Uncharacterized protein.	0.949
A0A182UM08	A0A182UQI8	A0A182UM08	A0A182UQI8	SAC domain-containing protein.	DUF1298 domain-containing protein.	0.638
A0A182UM08	A0A182UVH5	A0A182UM08	A0A182UVH5	SAC domain-containing protein.	Uncharacterized protein.	0.684
A0A182UM08	A0A182UWT6	A0A182UM08	A0A182UWT6	SAC domain-containing protein.	Uncharacterized protein.	0.702
A0A182UM08	A0A182UX43	A0A182UM08	A0A182UX43	SAC domain-containing protein.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.940
A0A182UM08	A0A182V1P2	A0A182UM08	A0A182V1P2	SAC domain-containing protein.	C2 NT-type domain-containing protein.	0.752
A0A182UM08	A0A182V2D1	A0A182UM08	A0A182V2D1	SAC domain-containing protein.	Rho-GAP domain-containing protein.	0.952
A0A182UM08	A0A182V2T7	A0A182UM08	A0A182V2T7	SAC domain-containing protein.	Uncharacterized protein.	0.902
A0A182UM08	A0A182V4Y5	A0A182UM08	A0A182V4Y5	SAC domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.702
A0A182UM08	A0A182V5Y0	A0A182UM08	A0A182V5Y0	SAC domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.638
A0A182UM08	A0A182V7A7	A0A182UM08	A0A182V7A7	SAC domain-containing protein.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.930
A0A182UM08	A0A182V7C6	A0A182UM08	A0A182V7C6	SAC domain-containing protein.	Uncharacterized protein.	0.944
A0A182UM08	A0A182V8E4	A0A182UM08	A0A182V8E4	SAC domain-containing protein.	IPPc domain-containing protein.	0.956
A0A182UM08	A0A182V8I1	A0A182UM08	A0A182V8I1	SAC domain-containing protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.959
A0A182UM08	A0A182V9M1	A0A182UM08	A0A182V9M1	SAC domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.908
A0A182UM08	A0A182VBA3	A0A182UM08	A0A182VBA3	SAC domain-containing protein.	Myotubularin phosphatase domain-containing protein.	0.919
A0A182UM08	A0A182VCV1	A0A182UM08	A0A182VCV1	SAC domain-containing protein.	IPPc domain-containing protein.	0.965
A0A182UM08	A0A182VDU3	A0A182UM08	A0A182VDU3	SAC domain-containing protein.	Uncharacterized protein.	0.915