(11 nodes) PIN-like domain superfamily network (Anopheles stephensi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	A0A182Y8T0	Uncharacterized protein. (820 aa)
	Fen1	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (408 aa)
	A0A182YLB4	Uncharacterized protein; Belongs to the RNR ribonuclease family. (961 aa)
	A0A182YRQ4	Uncharacterized protein. (743 aa)
	A0A182YM89	Uncharacterized protein. (582 aa)
	A0A182XVV7	PINc domain-containing protein. (470 aa)
	A0A182Y0E6	Uncharacterized protein. (1387 aa)
	A0A182Y3C6	Uncharacterized protein. (266 aa)
	A0A182Y4V2	PINc domain-containing protein. (370 aa)
	A0A182Y5K5	Uncharacterized protein. (884 aa)
	A0A182Y5V2	PINc domain-containing protein. (204 aa)

Your Current Organism:

Anopheles stephensi

NCBI taxonomy Id: 30069
Other names: A. stephensi, Anopheles mysorensis, Anopheles stephensi mysorensis, Anopheles stephensi var. mysorensis, Asian malaria mosquito

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182Y0E6	A0A182Y5K5	A0A182Y0E6	A0A182Y5K5	Uncharacterized protein.	Uncharacterized protein.	0.562
A0A182Y0E6	A0A182Y8T0	A0A182Y0E6	A0A182Y8T0	Uncharacterized protein.	Uncharacterized protein.	0.505
A0A182Y0E6	A0A182YM89	A0A182Y0E6	A0A182YM89	Uncharacterized protein.	Uncharacterized protein.	0.609
A0A182Y0E6	A0A182YRQ4	A0A182Y0E6	A0A182YRQ4	Uncharacterized protein.	Uncharacterized protein.	0.583
A0A182Y0E6	Fen1	A0A182Y0E6	A0A182YDD2	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.596
A0A182Y3C6	A0A182Y5V2	A0A182Y3C6	A0A182Y5V2	Uncharacterized protein.	PINc domain-containing protein.	0.897
A0A182Y5K5	A0A182Y0E6	A0A182Y5K5	A0A182Y0E6	Uncharacterized protein.	Uncharacterized protein.	0.562
A0A182Y5K5	A0A182Y8T0	A0A182Y5K5	A0A182Y8T0	Uncharacterized protein.	Uncharacterized protein.	0.646
A0A182Y5K5	A0A182YRQ4	A0A182Y5K5	A0A182YRQ4	Uncharacterized protein.	Uncharacterized protein.	0.608
A0A182Y5K5	Fen1	A0A182Y5K5	A0A182YDD2	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.608
A0A182Y5V2	A0A182Y3C6	A0A182Y5V2	A0A182Y3C6	PINc domain-containing protein.	Uncharacterized protein.	0.897
A0A182Y5V2	A0A182YLB4	A0A182Y5V2	A0A182YLB4	PINc domain-containing protein.	Uncharacterized protein; Belongs to the RNR ribonuclease family.	0.587
A0A182Y8T0	A0A182Y0E6	A0A182Y8T0	A0A182Y0E6	Uncharacterized protein.	Uncharacterized protein.	0.505
A0A182Y8T0	A0A182Y5K5	A0A182Y8T0	A0A182Y5K5	Uncharacterized protein.	Uncharacterized protein.	0.646
A0A182Y8T0	A0A182YM89	A0A182Y8T0	A0A182YM89	Uncharacterized protein.	Uncharacterized protein.	0.646
A0A182Y8T0	A0A182YRQ4	A0A182Y8T0	A0A182YRQ4	Uncharacterized protein.	Uncharacterized protein.	0.857
A0A182Y8T0	Fen1	A0A182Y8T0	A0A182YDD2	Uncharacterized protein.	Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]	0.913
A0A182YLB4	A0A182Y5V2	A0A182YLB4	A0A182Y5V2	Uncharacterized protein; Belongs to the RNR ribonuclease family.	PINc domain-containing protein.	0.587
A0A182YM89	A0A182Y0E6	A0A182YM89	A0A182Y0E6	Uncharacterized protein.	Uncharacterized protein.	0.609
A0A182YM89	A0A182Y8T0	A0A182YM89	A0A182Y8T0	Uncharacterized protein.	Uncharacterized protein.	0.646

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