(35 nodes) Chromosome Maintenance network (Anopheles stephensi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A182YMY0	BPL/LPL catalytic domain-containing protein. (541 aa)
	A0A182YHK5	Uncharacterized protein. (1417 aa)
	A0A182YGE9	PHD-type domain-containing protein. (2558 aa)
	A0A182YFY1	Uncharacterized protein. (506 aa)
	A0A182YAG9	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (229 aa)
	A0A182YAF2	3'-5' exonuclease domain-containing protein. (799 aa)
	A0A182YAD0	Uncharacterized protein. (1495 aa)
	A0A182YAC9	Uncharacterized protein. (688 aa)
	A0A182Y9V5	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
	A0A182Y947	AAA domain-containing protein. (1006 aa)
	A0A182Y5E8	Uncharacterized protein. (2068 aa)
	A0A182Y582	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (619 aa)
	A0A182Y4B1	Serine/threonine-protein phosphatase. (304 aa)
	A0A182Y398	Uncharacterized protein. (562 aa)
	A0A182Y341	TM2 domain-containing protein. (254 aa)
	A0A182Y2V0	Uncharacterized protein. (1631 aa)
	A0A182Y210	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (156 aa)
	A0A182Y0N6	RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (473 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (673 aa)
	A0A182XYW1	AAA domain-containing protein. (359 aa)
	A0A182XVN7	AAA domain-containing protein. (360 aa)
	A0A182YMV0	Rep_fac_C domain-containing protein. (358 aa)
	A0A182YL30	PHD-type domain-containing protein. (1355 aa)
	A0A182YKY9	SHQ1 domain-containing protein. (427 aa)
	A0A182YKA2	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (984 aa)
	A0A182YJU9	WD_REPEATS_REGION domain-containing protein. (442 aa)
	A0A182YTJ7	Uncharacterized protein. (123 aa)
	A0A182YT73	Uncharacterized protein. (142 aa)
	A0A182YT17	SLIDE domain-containing protein. (149 aa)
	A0A182YRV5	Uncharacterized protein. (419 aa)
	A0A182YQY4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A182YQF3	Nucleoplasmin domain-containing protein. (179 aa)
	A0A182YNQ6	AAA domain-containing protein. (327 aa)
	A0A182YNQ1	Uncharacterized protein. (64 aa)
	A0A182YNE8	Uncharacterized protein. (2221 aa)

Your Current Organism:

Anopheles stephensi

NCBI taxonomy Id: 30069
Other names: A. stephensi, Anopheles mysorensis, Anopheles stephensi mysorensis, Anopheles stephensi var. mysorensis, Asian malaria mosquito

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A182XVN7	A0A182XYW1	A0A182XVN7	A0A182XYW1	AAA domain-containing protein.	AAA domain-containing protein.	0.999
A0A182XVN7	A0A182Y2V0	A0A182XVN7	A0A182Y2V0	AAA domain-containing protein.	Uncharacterized protein.	0.805
A0A182XVN7	A0A182Y398	A0A182XVN7	A0A182Y398	AAA domain-containing protein.	Uncharacterized protein.	0.692
A0A182XVN7	A0A182Y582	A0A182XVN7	A0A182Y582	AAA domain-containing protein.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.910
A0A182XVN7	A0A182Y947	A0A182XVN7	A0A182Y947	AAA domain-containing protein.	AAA domain-containing protein.	0.988
A0A182XVN7	A0A182Y9V5	A0A182XVN7	A0A182Y9V5	AAA domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.461
A0A182XVN7	A0A182YAC9	A0A182XVN7	A0A182YAC9	AAA domain-containing protein.	Uncharacterized protein.	0.421
A0A182XVN7	A0A182YAD0	A0A182XVN7	A0A182YAD0	AAA domain-containing protein.	Uncharacterized protein.	0.421
A0A182XVN7	A0A182YAF2	A0A182XVN7	A0A182YAF2	AAA domain-containing protein.	3'-5' exonuclease domain-containing protein.	0.562
A0A182XVN7	A0A182YKA2	A0A182XVN7	A0A182YKA2	AAA domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.974
A0A182XVN7	A0A182YMV0	A0A182XVN7	A0A182YMV0	AAA domain-containing protein.	Rep_fac_C domain-containing protein.	0.999
A0A182XVN7	A0A182YMY0	A0A182XVN7	A0A182YMY0	AAA domain-containing protein.	BPL/LPL catalytic domain-containing protein.	0.562
A0A182XVN7	A0A182YNQ6	A0A182XVN7	A0A182YNQ6	AAA domain-containing protein.	AAA domain-containing protein.	0.999
A0A182XVN7	A0A182YQY4	A0A182XVN7	A0A182YQY4	AAA domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.461
A0A182XVN7	A0A182YRV5	A0A182XVN7	A0A182YRV5	AAA domain-containing protein.	Uncharacterized protein.	0.969
A0A182XVN7	A0A182YT17	A0A182XVN7	A0A182YT17	AAA domain-containing protein.	SLIDE domain-containing protein.	0.421
A0A182XVN7	A0A182YT73	A0A182XVN7	A0A182YT73	AAA domain-containing protein.	Uncharacterized protein.	0.929
A0A182XVN7	A0A182YTJ7	A0A182XVN7	A0A182YTJ7	AAA domain-containing protein.	Uncharacterized protein.	0.929
A0A182XYW1	A0A182XVN7	A0A182XYW1	A0A182XVN7	AAA domain-containing protein.	AAA domain-containing protein.	0.999
A0A182XYW1	A0A182Y2V0	A0A182XYW1	A0A182Y2V0	AAA domain-containing protein.	Uncharacterized protein.	0.791

page 1 of 19

Server load: low (28%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About