STRINGSTRING
tp53bp1 tp53bp1 topbp1 topbp1 atr atr atm atm LOC102215705 LOC102215705 tp63 tp63 mdc1 mdc1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
tp53bp1Tumor protein p53 binding protein, 1. (1473 aa)
topbp1DNA topoisomerase II binding protein 1. (1425 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2444 aa)
atmNon-specific serine/threonine protein kinase. (3051 aa)
LOC102215705Checkpoint kinase 2. (476 aa)
tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (623 aa)
mdc1Uncharacterized protein. (1729 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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