37 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sf3a3	Splicing factor 3a, subunit 3. (501 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (892 aa)
	sf3b5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast). (507 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (123 aa)
	snrnp70	Small nuclear ribonucleoprotein 70 (U1). (475 aa)
	snrpa1	Small nuclear ribonucleoprotein polypeptide A. (243 aa)
	sf3b3	Splicing factor 3b, subunit 3. (1217 aa)
	prpf3	PRP3 pre-mRNA processing factor 3 homolog (yeast). (723 aa)
	phf5a	PHD finger protein 5A. (110 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (134 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (280 aa)
	sf3a2	Splicing factor 3a, subunit 2. (294 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (510 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (959 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (971 aa)
	sf3b4	Splicing factor 3b, subunit 4. (401 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	SART1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (769 aa)
	snrpb	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	sf3b1	Splicing factor 3b, subunit 1. (1311 aa)
	snrpb2	Small nuclear ribonucleoprotein polypeptide B2. (247 aa)
	prpf8	Pre-mRNA processing factor 8. (2333 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2063 aa)
	sf3a1	Splicing factor 3a, subunit 1. (784 aa)
	lsm2	Smx5. (140 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (832 aa)
	ENSPNYP00000028858	Small nuclear ribonucleoprotein polypeptide F. (85 aa)
	sf3b6	Splicing factor 3b, subunit 6. (125 aa)
	sf3b2	Splicing factor 3b, subunit 2. (740 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000028858	LSM10	ENSPNYP00000028858	ENSPNYP00000004039	Small nuclear ribonucleoprotein polypeptide F.	LSM10, U7 small nuclear RNA associated.	0.999
ENSPNYP00000028858	SART1	ENSPNYP00000028858	ENSPNYP00000019537	Small nuclear ribonucleoprotein polypeptide F.	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.993
ENSPNYP00000028858	SNRPC	ENSPNYP00000028858	ENSPNYP00000006382	Small nuclear ribonucleoprotein polypeptide F.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.996
ENSPNYP00000028858	ddx23	ENSPNYP00000028858	ENSPNYP00000027966	Small nuclear ribonucleoprotein polypeptide F.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.983
ENSPNYP00000028858	ddx46	ENSPNYP00000028858	ENSPNYP00000016329	Small nuclear ribonucleoprotein polypeptide F.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	0.980
ENSPNYP00000028858	eftud2	ENSPNYP00000028858	ENSPNYP00000016503	Small nuclear ribonucleoprotein polypeptide F.	Elongation factor Tu GTP binding domain containing 2.	0.999
ENSPNYP00000028858	lsm2	ENSPNYP00000028858	ENSPNYP00000025572	Small nuclear ribonucleoprotein polypeptide F.	Smx5.	0.998
ENSPNYP00000028858	lsm3	ENSPNYP00000028858	ENSPNYP00000012583	Small nuclear ribonucleoprotein polypeptide F.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.989
ENSPNYP00000028858	lsm8	ENSPNYP00000028858	ENSPNYP00000015100	Small nuclear ribonucleoprotein polypeptide F.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.993
ENSPNYP00000028858	phf5a	ENSPNYP00000028858	ENSPNYP00000005658	Small nuclear ribonucleoprotein polypeptide F.	PHD finger protein 5A.	0.997
ENSPNYP00000028858	prpf3	ENSPNYP00000028858	ENSPNYP00000005580	Small nuclear ribonucleoprotein polypeptide F.	PRP3 pre-mRNA processing factor 3 homolog (yeast).	0.975
ENSPNYP00000028858	prpf31	ENSPNYP00000028858	ENSPNYP00000002881	Small nuclear ribonucleoprotein polypeptide F.	PRP31 pre-mRNA processing factor 31 homolog (yeast).	0.985
ENSPNYP00000028858	prpf4	ENSPNYP00000028858	ENSPNYP00000010584	Small nuclear ribonucleoprotein polypeptide F.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.981
ENSPNYP00000028858	prpf6	ENSPNYP00000028858	ENSPNYP00000002511	Small nuclear ribonucleoprotein polypeptide F.	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).	0.996
ENSPNYP00000028858	prpf8	ENSPNYP00000028858	ENSPNYP00000021743	Small nuclear ribonucleoprotein polypeptide F.	Pre-mRNA processing factor 8.	0.998
ENSPNYP00000028858	sf3a1	ENSPNYP00000028858	ENSPNYP00000024807	Small nuclear ribonucleoprotein polypeptide F.	Splicing factor 3a, subunit 1.	0.980
ENSPNYP00000028858	sf3a2	ENSPNYP00000028858	ENSPNYP00000009103	Small nuclear ribonucleoprotein polypeptide F.	Splicing factor 3a, subunit 2.	0.978
ENSPNYP00000028858	sf3a3	ENSPNYP00000028858	ENSPNYP00000000980	Small nuclear ribonucleoprotein polypeptide F.	Splicing factor 3a, subunit 3.	0.987
ENSPNYP00000028858	sf3b1	ENSPNYP00000028858	ENSPNYP00000019804	Small nuclear ribonucleoprotein polypeptide F.	Splicing factor 3b, subunit 1.	0.991
ENSPNYP00000028858	sf3b2	ENSPNYP00000028858	ENSPNYP00000031295	Small nuclear ribonucleoprotein polypeptide F.	Splicing factor 3b, subunit 2.	0.982