STRINGSTRING
exosc7 exosc7 pin4 pin4 imp3 imp3 drosha drosha LOC102213344 LOC102213344 mrm1 mrm1 kri1 kri1 znhit2 znhit2 LOC102195968 LOC102195968 rpl7 rpl7 nop53 nop53 wdr17 wdr17 ddx10 ddx10 ENSPNYP00000002565 ENSPNYP00000002565 nsa2 nsa2 zcchc4 zcchc4 utp6 utp6 ENSPNYP00000003100 ENSPNYP00000003100 exosc3 exosc3 nsun4 nsun4 pop5 pop5 lyar lyar ENSPNYP00000003560 ENSPNYP00000003560 rsl1d1 rsl1d1 rrp8 rrp8 riok3 riok3 dcaf13 dcaf13 pdcd11 pdcd11 nsun3 nsun3 rpp38 rpp38 rpp40 rpp40 riok1 riok1 LOC102214041 LOC102214041 rbm34 rbm34 gnl3 gnl3 ftsj3 ftsj3 mphosph10 mphosph10 LOC102196563 LOC102196563 mak16 mak16 mettl15 mettl15 ENSPNYP00000007312 ENSPNYP00000007312 rpl35 rpl35 bud23 bud23 mphosph6 mphosph6 mtrex mtrex wdr3 wdr3 mrpl1 mrpl1 mettl5 mettl5 ERI2 ERI2 ddx54 ddx54 ENSPNYP00000009622 ENSPNYP00000009622 utp15 utp15 tfb1m tfb1m exosc2 exosc2 exosc10 exosc10 brix1 brix1 bysl bysl nvl nvl nop14 nop14 dhx37 dhx37 LOC102195041 LOC102195041 wdr74 wdr74 mrps11 mrps11 c1d c1d LOC102212750 LOC102212750 mrm2 mrm2 rrp15 rrp15 npm3 npm3 nsun5 nsun5 mrpl44 mrpl44 gemin4 gemin4 rrp12 rrp12 pwp1 pwp1 LOC102206698 LOC102206698 rpl7l1 rpl7l1 srfbp1 srfbp1 wdr46 wdr46 helq helq exosc6 exosc6 ENSPNYP00000014227 ENSPNYP00000014227 urb1 urb1 bop1 bop1 ENSPNYP00000014631 ENSPNYP00000014631 ENSPNYP00000014665 ENSPNYP00000014665 rrnad1 rrnad1 LOC102211940 LOC102211940 rps25 rps25 utp20 utp20 trmt2b trmt2b wdr36 wdr36 wdr75 wdr75 ybey ybey lsm6 lsm6 rcl1 rcl1 fdxacb1 fdxacb1 exosc8 exosc8 utp11 utp11 ngdn ngdn wdr18 wdr18 rexo4 rexo4 fbl fbl exosc4 exosc4 pih1d1 pih1d1 rrp9 rrp9 ddx27 ddx27 SART1 SART1 frg1 frg1 ddx21 ddx21 esf1 esf1 pih1d2 pih1d2 wdr43 wdr43 trmt61b trmt61b nop2 nop2 emg1 emg1 wdr55 wdr55 UTP25 UTP25 rpusd1 rpusd1 rpf1 rpf1 UTP14C UTP14C nhp2 nhp2 ercc2 ercc2 nat10 nat10 eri1 eri1 rpusd2 rpusd2 nol9 nol9 naf1 naf1 nop10 nop10 gar1 gar1 ddx52 ddx52 nol6 nol6 krr1 krr1 ddx47 ddx47 wbp11 wbp11 nol10 nol10 rrp7a rrp7a dkc1 dkc1 pop4 pop4 tsr2 tsr2 abt1 abt1 nop9 nop9 imp4 imp4 EIF6 EIF6 prkdc prkdc dimt1 dimt1 LOC102207990 LOC102207990 ddx56 ddx56 wdr12 wdr12 bms1 bms1 riok2 riok2 mrto4 mrto4 nob1 nob1 nol11 nol11 tex10 tex10 LOC102198987 LOC102198987 RRP36 RRP36 utp3 utp3 utp23 utp23 ENSPNYP00000023311 ENSPNYP00000023311 tfb2m tfb2m tsr3 tsr3 pelp1 pelp1 tbl3 tbl3 utp4 utp4 pes1 pes1 znhit3 znhit3 ebna1bp2 ebna1bp2 ENSPNYP00000022512 ENSPNYP00000022512 mrm3 mrm3 ZNHIT6 ZNHIT6 ddx49 ddx49 mettl16 mettl16 fam207a fam207a ddx18 ddx18 nifk nifk tsr1 tsr1 gtpbp4 gtpbp4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
exosc7Exosome component 7. (291 aa)
pin4Peptidyl-prolyl cis-trans isomerase. (127 aa)
imp3IMP U3 small nucleolar ribonucleoprotein 3. (183 aa)
droshaDrosha ribonuclease III. (1345 aa)
LOC102213344Uncharacterized protein. (680 aa)
mrm1Mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae). (293 aa)
kri1KRI1 homolog. (741 aa)
znhit2Zinc finger, HIT-type containing 2. (572 aa)
LOC102195968SpoU_sub_bind domain-containing protein. (433 aa)
rpl7Ribosomal protein L7. (245 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (464 aa)
wdr17WD repeat domain 17. (1263 aa)
ddx10RNA helicase. (850 aa)
ENSPNYP00000002565RRM domain-containing protein. (107 aa)
nsa2NSA2 ribosome biogenesis homolog (S. cerevisiae). (260 aa)
zcchc4Zinc finger, CCHC domain containing 4. (496 aa)
utp6UTP6 small subunit processome component. (595 aa)
ENSPNYP00000003100Uncharacterized protein. (79 aa)
exosc3Exosome component 3. (244 aa)
nsun4NOP2/Sun RNA methyltransferase 4; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (392 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (168 aa)
lyarLy1 antibody reactive homolog (mouse). (344 aa)
ENSPNYP00000003560Uncharacterized protein. (126 aa)
rsl1d1Ribosomal L1 domain containing 1. (364 aa)
rrp8Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (531 aa)
riok3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (508 aa)
dcaf13Ddb1 and cul4 associated factor 13. (445 aa)
pdcd11Programmed cell death 11. (1805 aa)
nsun3NOP2/Sun RNA methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (394 aa)
rpp38Ribonuclease P/MRP 38 subunit. (264 aa)
rpp40Ribonuclease P/MRP 40 subunit. (280 aa)
riok1RIO kinase 1 (yeast). (313 aa)
LOC102214041Uncharacterized protein. (106 aa)
rbm34RNA binding motif protein 34. (425 aa)
gnl3Guanine nucleotide binding protein-like 3 (nucleolar). (480 aa)
ftsj3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (734 aa)
mphosph10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (679 aa)
LOC102196563Peptidase_M24 domain-containing protein. (391 aa)
mak16Protein MAK16 homolog; Belongs to the MAK16 family. (275 aa)
mettl15Methyltransferase like 15. (388 aa)
ENSPNYP00000007312WD repeat domain 55. (353 aa)
rpl35Ribosomal protein L35. (123 aa)
bud23BUD23 rRNA methyltransferase and ribosome maturation factor. (282 aa)
mphosph6M-phase phosphoprotein 6. (158 aa)
mtrexMtr4 exosome RNA helicase. (1037 aa)
wdr3WD repeat domain 3. (911 aa)
mrpl1Mitochondrial ribosomal protein L1. (322 aa)
mettl5Methyltransferase like 5. (235 aa)
ERI2ERI1 exoribonuclease family member 2. (526 aa)
ddx54ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (468 aa)
ENSPNYP00000009622ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (89 aa)
utp15UTP15 small subunit processome component. (528 aa)
tfb1mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (360 aa)
exosc2Exosome component 2. (293 aa)
exosc10Exosome component 10. (890 aa)
brix1Brix domain containing 2. (342 aa)
byslBystin-like. (435 aa)
nvlNuclear VCP like. (858 aa)
nop14NOP14 nucleolar protein homolog (yeast). (862 aa)
dhx37DEAH (Asp-Glu-Ala-His) box polypeptide 37. (1098 aa)
LOC102195041PWP2 small subunit processome component. (723 aa)
wdr74WD repeat domain 74. (375 aa)
mrps11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (196 aa)
c1dC1D nuclear receptor corepressor. (152 aa)
LOC102212750Mitochondrial transcription termination factor 4. (334 aa)
mrm2Mitochondrial rRNA methyltransferase 2. (239 aa)
rrp15Ribosomal RNA processing 15 homolog. (241 aa)
npm3Nucleophosmin/nucleoplasmin, 3. (161 aa)
nsun5NOP2/Sun RNA methyltransferase 5; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (495 aa)
mrpl44Mitochondrial ribosomal protein L44. (332 aa)
gemin4Gem (nuclear organelle) associated protein 4. (1114 aa)
rrp12Ribosomal RNA processing 12 homolog. (1288 aa)
pwp1PWP1 homolog, endonuclein. (484 aa)
LOC102206698RNA pseudouridine synthase D4. (387 aa)
rpl7l1Ribosomal protein L7-like 1. (255 aa)
srfbp1BUD22 domain-containing protein. (536 aa)
wdr46WD repeat domain 46. (597 aa)
helqHelicase, POLQ like. (912 aa)
exosc6Exosome component 6. (274 aa)
ENSPNYP00000014227Uncharacterized protein. (59 aa)
urb1URB1 ribosome biogenesis homolog. (2138 aa)
bop1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (679 aa)
ENSPNYP00000014631U3snoRNP10 domain-containing protein. (326 aa)
ENSPNYP00000014665BP28CT domain-containing protein. (333 aa)
rrnad1Ribosomal RNA adenine dimethylase domain containing 1. (554 aa)
LOC102211940Ribonuclease P and MRP subunit p25, b. (235 aa)
rps2540S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (123 aa)
utp20UTP20 small subunit processome component. (2794 aa)
trmt2btRNA methyltransferase 2 homolog B; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (480 aa)
wdr36WD repeat domain 36. (889 aa)
wdr75WD repeat domain 75. (837 aa)
ybeyYbeY metalloendoribonuclease. (168 aa)
lsm6LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (81 aa)
rcl1RNA terminal phosphate cyclase-like 1. (372 aa)
fdxacb1Ferredoxin-fold anticodon binding domain containing 1. (639 aa)
exosc8Exosome component 8. (297 aa)
utp11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (254 aa)
ngdnNeuroguidin, EIF4E binding protein. (325 aa)
wdr18WD repeat domain 18. (431 aa)
rexo4REX4 homolog, 3'-5' exonuclease. (427 aa)
fblFibrillarin. (315 aa)
exosc4Exosome component 4. (278 aa)
pih1d1PIH1 domain containing 1. (287 aa)
rrp9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (482 aa)
ddx27DEAD (Asp-Glu-Ala-Asp) box polypeptide 27; Belongs to the DEAD box helicase family. (639 aa)
SART1Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (769 aa)
frg1FSHD region gene 1. (232 aa)
ddx21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (622 aa)
esf1ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae). (742 aa)
pih1d2PIH1 domain containing 2. (315 aa)
wdr43WD repeat domain 43. (650 aa)
trmt61btRNA methyltransferase 61B. (487 aa)
nop2NOP2 nucleolar protein homolog (yeast); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (706 aa)
emg1EMG1 N1-specific pseudouridine methyltransferase. (237 aa)
wdr55WD repeat domain 55. (174 aa)
UTP25UTP25 small subunit processor component. (592 aa)
rpusd1RNA pseudouridine synthase domain containing 1. (311 aa)
rpf1Ribosome production factor 1 homolog. (349 aa)
UTP14CUTP14C small subunit processome component. (775 aa)
nhp2Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (154 aa)
ercc2Excision repair cross-complementation group 2. (760 aa)
nat10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1035 aa)
eri1Exoribonuclease 1. (341 aa)
rpusd2Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (494 aa)
nol9Nucleolar protein 9. (699 aa)
naf1Uncharacterized protein. (387 aa)
nop10NOP10 ribonucleoprotein homolog (yeast). (64 aa)
gar1H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (240 aa)
ddx52DEAD (Asp-Glu-Ala-Asp) box polypeptide 52. (581 aa)
nol6Nucleolar protein 6. (1138 aa)
krr1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (386 aa)
ddx47DEAD (Asp-Glu-Ala-Asp) box polypeptide 47; Belongs to the DEAD box helicase family. (481 aa)
wbp11Uncharacterized protein. (737 aa)
nol10Nucleolar protein 10. (725 aa)
rrp7aRibosomal RNA processing 7 homolog A. (282 aa)
dkc1Dyskeratosis congenita 1, dyskerin. (502 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (221 aa)
tsr2TSR2 ribosome maturation factor. (219 aa)
abt1Activator of basal transcription 1. (324 aa)
nop9Uncharacterized protein. (613 aa)
imp4IMP U3 small nucleolar ribonucleoprotein 4. (291 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (222 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (3978 aa)
dimt1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (306 aa)
LOC102207990UTP25 small subunit processor component. (670 aa)
ddx56DEAD (Asp-Glu-Ala-Asp) box helicase 56. (560 aa)
wdr12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (421 aa)
bms1BMS1 ribosome biogenesis factor. (1208 aa)
riok2RIO kinase 2 (yeast). (525 aa)
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
nob1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (480 aa)
nol11Nucleolar protein 11. (719 aa)
tex10Testis expressed 10. (943 aa)
LOC102198987Proliferation-associated 2G4, b. (392 aa)
RRP36Ribosomal RNA processing 36. (322 aa)
utp3UTP3 small subunit processome component. (432 aa)
utp23UTP23 small subunit processome component. (254 aa)
ENSPNYP00000023311UTP18 small subunit processome component. (101 aa)
tfb2mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (453 aa)
tsr3Probable ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis. (295 aa)
pelp1Proline, glutamate and leucine rich protein 1. (1036 aa)
tbl3Transducin (beta)-like 3. (750 aa)
utp4UTP4 small subunit processome component. (684 aa)
pes1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (563 aa)
znhit3Zinc finger, HIT-type containing 3. (145 aa)
ebna1bp2EBNA1 binding protein 2. (314 aa)
ENSPNYP00000022512Uncharacterized protein. (281 aa)
mrm3Mitochondrial rRNA methyltransferase 3a. (448 aa)
ZNHIT6Zinc finger HIT-type containing 6. (350 aa)
ddx49DEAD (Asp-Glu-Ala-Asp) box polypeptide 49; Belongs to the DEAD box helicase family. (472 aa)
mettl16U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (521 aa)
fam207aFamily with sequence similarity 207 member A. (253 aa)
ddx18RNA helicase. (656 aa)
nifkNucleolar protein interacting with the FHA domain of MKI67. (275 aa)
tsr1TSR1 ribosome maturation factor. (828 aa)
gtpbp4GTP binding protein 4. (565 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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