(20 nodes) Response to zinc ion network (Pundamilia nyererei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	slc30a8	Solute carrier family 30 member 8. (371 aa)
	LOC102204520	Glycine receptor, alpha 4b; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (467 aa)
	LOC102204691	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (60 aa)
	slc30a3	Solute carrier family 30 member 2. (365 aa)
	LOC102211999	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
	slc39a10	Uncharacterized protein. (841 aa)
	mtf1	Metal-regulatory transcription factor 1. (796 aa)
	khk	Ketohexokinase. (333 aa)
	slc39a6	Solute carrier family 39 member 6. (619 aa)
	slc30a5	Solute carrier family 30 member 5. (773 aa)
	p2rx5	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (459 aa)
	glra2	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (402 aa)
	hvcn1	Hydrogen voltage-gated channel 1. (226 aa)
	slc30a1	Solute carrier family 30 member 1a. (488 aa)
	ENSPNYP00000001661	Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (424 aa)
	glra1	Glycine receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (461 aa)
	pam	Peptidylglycine alpha-amidating monooxygenase. (829 aa)
	p2rx7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (580 aa)
	slc30a4	Solute carrier family 30 member 4. (438 aa)
	LOC102200790	Glycine receptor, alpha 4a; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (419 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000001661	glra2	ENSPNYP00000001661	ENSPNYP00000015667	Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.813
LOC102204691	slc30a1	ENSPNYP00000025438	ENSPNYP00000030697	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	Solute carrier family 30 member 1a.	0.457
LOC102211999	p2rx7	ENSPNYP00000017609	ENSPNYP00000009993	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.879
glra1	glra2	ENSPNYP00000004048	ENSPNYP00000015667	Glycine receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.811
glra2	ENSPNYP00000001661	ENSPNYP00000015667	ENSPNYP00000001661	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Glycine receptor, alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.813
glra2	glra1	ENSPNYP00000015667	ENSPNYP00000004048	Glycine receptor, alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	Glycine receptor, alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family.	0.811
mtf1	slc30a1	ENSPNYP00000018401	ENSPNYP00000030697	Metal-regulatory transcription factor 1.	Solute carrier family 30 member 1a.	0.416
mtf1	slc30a3	ENSPNYP00000018401	ENSPNYP00000001189	Metal-regulatory transcription factor 1.	Solute carrier family 30 member 2.	0.407
p2rx5	p2rx7	ENSPNYP00000023171	ENSPNYP00000009993	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.879
p2rx7	LOC102211999	ENSPNYP00000009993	ENSPNYP00000017609	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.879
p2rx7	p2rx5	ENSPNYP00000009993	ENSPNYP00000023171	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.879
slc30a1	LOC102204691	ENSPNYP00000030697	ENSPNYP00000025438	Solute carrier family 30 member 1a.	Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals.	0.457
slc30a1	mtf1	ENSPNYP00000030697	ENSPNYP00000018401	Solute carrier family 30 member 1a.	Metal-regulatory transcription factor 1.	0.416
slc30a1	slc30a3	ENSPNYP00000030697	ENSPNYP00000001189	Solute carrier family 30 member 1a.	Solute carrier family 30 member 2.	0.442
slc30a1	slc30a4	ENSPNYP00000030697	ENSPNYP00000011222	Solute carrier family 30 member 1a.	Solute carrier family 30 member 4.	0.455
slc30a1	slc30a5	ENSPNYP00000030697	ENSPNYP00000022476	Solute carrier family 30 member 1a.	Solute carrier family 30 member 5.	0.478
slc30a1	slc30a8	ENSPNYP00000030697	ENSPNYP00000023259	Solute carrier family 30 member 1a.	Solute carrier family 30 member 8.	0.447
slc30a1	slc39a10	ENSPNYP00000030697	ENSPNYP00000017931	Solute carrier family 30 member 1a.	Uncharacterized protein.	0.571
slc30a1	slc39a6	ENSPNYP00000030697	ENSPNYP00000021932	Solute carrier family 30 member 1a.	Solute carrier family 39 member 6.	0.571
slc30a3	mtf1	ENSPNYP00000001189	ENSPNYP00000018401	Solute carrier family 30 member 2.	Metal-regulatory transcription factor 1.	0.407