(105 nodes) Protein phosphatase binding network (Pundamilia nyererei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nek2	NIMA-related kinase 2. (428 aa)
	ENSPNYP00000031399	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (349 aa)
	LOC102211657	Phosphatase and actin regulator. (496 aa)
	kifap3	Kinesin-associated protein 3b. (722 aa)
	LOC102193387	Protein phosphatase 1, regulatory subunit 16B. (520 aa)
	smg5	SMG5 nonsense mediated mRNA decay factor. (1129 aa)
	pdlim4	PDZ and LIM domain 4. (364 aa)
	strn3	Striatin, calmodulin binding protein 3. (706 aa)
	LOC102206613	Phosphatase and actin regulator. (586 aa)
	STRN	Striatin. (779 aa)
	LOC102194045	CTTNBP2 N-terminal like b. (570 aa)
	vrk3	VRK serine/threonine kinase 3. (515 aa)
	ENSPNYP00000019974	CBM21 domain-containing protein. (275 aa)
	skap2	Src kinase associated phosphoprotein 2. (333 aa)
	LOC102192550	Striatin, calmodulin binding protein. (741 aa)
	LOC102213257	PDZ domain-containing protein. (878 aa)
	cdc27	Cell division cycle 27. (833 aa)
	adcy8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa)
	ENSPNYP00000021619	Zgc:77112. (260 aa)
	ENSPNYP00000022138	Uncharacterized protein. (446 aa)
	map2k7	Mitogen-activated protein kinase kinase 7. (439 aa)
	LOC102196479	Protein phosphatase 1 regulatory subunit. (334 aa)
	MTMR4	Myotubularin related protein 4. (1200 aa)
	eif2ak3	Eukaryotic translation initiation factor 2-alpha kinase 3. (933 aa)
	stx17	Syntaxin 17; Belongs to the syntaxin family. (307 aa)
	ppp6r3	Protein phosphatase 6, regulatory subunit 3. (915 aa)
	ENSPNYP00000024676	CBM21 domain-containing protein. (285 aa)
	strn4	Striatin, calmodulin binding protein 4. (763 aa)
	ppp1r9a	Protein phosphatase 1, regulatory subunit 9A. (972 aa)
	LOC102212081	Protein phosphatase 6, regulatory subunit 2a. (810 aa)
	ARPP19	cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (112 aa)
	ppme1	Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. (377 aa)
	bad	BCL2 associated agonist of cell death b. (158 aa)
	LOC102214456	Galectin. (376 aa)
	LOC102210106	Si:ch211-74f19.2. (172 aa)
	LOC102199243	BH4_2 domain-containing protein. (198 aa)
	ENSPNYP00000029507	Ig-like domain-containing protein. (238 aa)
	LOC102203386	Protein phosphatase 1, regulatory subunit 16A. (224 aa)
	LOC102197926	Uncharacterized protein. (996 aa)
	LOC102216058	Uncharacterized protein. (844 aa)
	skap1	Src kinase associated phosphoprotein 1. (311 aa)
	ppp1r3c	Protein phosphatase 1 regulatory subunit. (345 aa)
	ENSPNYP00000001645	Galectin. (94 aa)
	hsp90b1	Heat shock protein 90, beta (grp94), member 1. (796 aa)
	arpp19	cAMP-regulated phosphoprotein 19b; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (116 aa)
	ambra1	Autophagy/beclin-1 regulator 1b. (1181 aa)
	anapc5	Anaphase promoting complex subunit 5. (721 aa)
	shoc2	SHOC2 leucine rich repeat scaffold protein. (570 aa)
	kcnq1	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (621 aa)
	LOC102214474	Uncharacterized protein. (711 aa)
	LOC102207241	Junction plakoglobin a. (728 aa)
	kcnn4	Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4. (486 aa)
	mastl	Microtubule associated serine/threonine kinase-like. (803 aa)
	ptpa	Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (324 aa)
	LOC102205956	Protein phosphatase 1, regulatory subunit 9Bb. (798 aa)
	ankle2	Ankyrin repeat and LEM domain containing 2. (971 aa)
	ENSPNYP00000006117	PDZ domain-containing protein. (100 aa)
	phactr3	Phosphatase and actin regulator. (526 aa)
	ENSPNYP00000006620	Protein phosphatase 1, regulatory subunit 3Db. (282 aa)
	LOC102206298	Zgc:154055. (524 aa)
	igbp1	Immunoglobulin (CD79A) binding protein 1. (360 aa)
	phactr4	Phosphatase and actin regulator. (756 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1108 aa)
	mtmr9	Myotubularin related protein 9. (549 aa)
	LOC102195781	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (780 aa)
	LOC102204844	Uncharacterized protein; Belongs to the potassium channel family. (643 aa)
	mtmr3	Myotubularin related protein 3. (1242 aa)
	LOC102210859	Protein phosphatase 1 regulatory subunit 9A-like A. (1433 aa)
	anapc7	Anaphase promoting complex subunit 7. (565 aa)
	smg7	SMG7 nonsense mediated mRNA decay factor. (1184 aa)
	ENSPNYP00000010339	Uncharacterized protein. (164 aa)
	ppp6r2	Protein phosphatase 6, regulatory subunit 2b. (928 aa)
	LOC102195941	Galectin. (242 aa)
	ENSPNYP00000010907	Protein phosphatase 1, regulatory subunit 3Da. (271 aa)
	ENSPNYP00000010945	Phosphatase and actin regulator. (376 aa)
	LOC102203802	Uncharacterized protein. (768 aa)
	LOC102197094	CBM21 domain-containing protein. (356 aa)
	AP3B2	AP-3 complex subunit beta. (1047 aa)
	fbxo41	F-box protein 41. (816 aa)
	ppp1r3g	Si:ch211-152c8.5. (266 aa)
	LOC102214200	Si:ch211-152c8.5. (227 aa)
	LOC102199476	Smoothelin, like. (556 aa)
	LOC102192308	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (971 aa)
	LOC102201344	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (255 aa)
	ENSPNYP00000013178	Adaptin_N domain-containing protein. (141 aa)
	LOC102194175	Phosphatase and actin regulator 4a. (1052 aa)
	fbxl2	F-box and leucine-rich repeat protein 2. (432 aa)
	styxl1	Serine/threonine/tyrosine interacting-like 1. (294 aa)
	ppp1r11	Protein phosphatase 1, regulatory (inhibitor) subunit 11. (123 aa)
	GRIN3A	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1079 aa)
	mfhas1	Malignant fibrous histiocytoma amplified sequence 1. (991 aa)
	LOC102214228	Protein phosphatase 1, regulatory subunit 15B. (564 aa)
	ENSPNYP00000014344	Protein phosphatase 1 regulatory subunit. (296 aa)
	LOC102211635	Calponin-homology (CH) domain-containing protein. (597 aa)
	LOC102212583	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (255 aa)
	akap11	A kinase (PRKA) anchor protein 11. (1878 aa)
	ppp1r10	Protein phosphatase 1, regulatory subunit 10. (790 aa)
	ctnnb1	Catenin (cadherin-associated protein), beta 1. (783 aa)
	LOC102216196	F-box and leucine-rich repeat protein 20. (436 aa)
	anapc4	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (780 aa)
	mvp	Major vault protein. (842 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC102199757	Endosulfine alpha a; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (116 aa)
	gtf2f1	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (542 aa)
	cttnbp2nl	CTTNBP2 N-terminal like a. (605 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B1	AP3B2	ENSPNYP00000008152	ENSPNYP00000012156	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	AP-3 complex subunit beta.	0.882
AP3B2	AP3B1	ENSPNYP00000012156	ENSPNYP00000008152	AP-3 complex subunit beta.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.882
AP3B2	ENSPNYP00000013178	ENSPNYP00000012156	ENSPNYP00000013178	AP-3 complex subunit beta.	Adaptin_N domain-containing protein.	0.822
ARPP19	mastl	ENSPNYP00000026935	ENSPNYP00000004285	cAMP regulated phosphoprotein 19; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family.	Microtubule associated serine/threonine kinase-like.	0.844
ENSPNYP00000010907	LOC102196479	ENSPNYP00000010907	ENSPNYP00000022292	Protein phosphatase 1, regulatory subunit 3Da.	Protein phosphatase 1 regulatory subunit.	0.546
ENSPNYP00000013178	AP3B2	ENSPNYP00000013178	ENSPNYP00000012156	Adaptin_N domain-containing protein.	AP-3 complex subunit beta.	0.822
ENSPNYP00000014344	LOC102196479	ENSPNYP00000014344	ENSPNYP00000022292	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1 regulatory subunit.	0.828
ENSPNYP00000014344	LOC102197094	ENSPNYP00000014344	ENSPNYP00000011912	Protein phosphatase 1 regulatory subunit.	CBM21 domain-containing protein.	0.818
ENSPNYP00000014344	ppp1r3c	ENSPNYP00000014344	ENSPNYP00000001032	Protein phosphatase 1 regulatory subunit.	Protein phosphatase 1 regulatory subunit.	0.818
ENSPNYP00000029507	skap1	ENSPNYP00000029507	ENSPNYP00000000831	Ig-like domain-containing protein.	Src kinase associated phosphoprotein 1.	0.630
ENSPNYP00000029507	skap2	ENSPNYP00000029507	ENSPNYP00000020245	Ig-like domain-containing protein.	Src kinase associated phosphoprotein 2.	0.630
ENSPNYP00000031399	hsp90b1	ENSPNYP00000031399	ENSPNYP00000001681	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Heat shock protein 90, beta (grp94), member 1.	0.403
GRIN3A	anapc4	ENSPNYP00000013913	ENSPNYP00000015490	Glutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.	Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.	0.680
LOC102192308	hsp90b1	ENSPNYP00000012756	ENSPNYP00000001681	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Heat shock protein 90, beta (grp94), member 1.	0.403
LOC102192550	LOC102194045	ENSPNYP00000020308	ENSPNYP00000019208	Striatin, calmodulin binding protein.	CTTNBP2 N-terminal like b.	0.754
LOC102192550	cttnbp2nl	ENSPNYP00000020308	ENSPNYP00000017175	Striatin, calmodulin binding protein.	CTTNBP2 N-terminal like a.	0.754
LOC102192550	map2k7	ENSPNYP00000020308	ENSPNYP00000022178	Striatin, calmodulin binding protein.	Mitogen-activated protein kinase kinase 7.	0.859
LOC102194045	LOC102192550	ENSPNYP00000019208	ENSPNYP00000020308	CTTNBP2 N-terminal like b.	Striatin, calmodulin binding protein.	0.754
LOC102194045	STRN	ENSPNYP00000019208	ENSPNYP00000019073	CTTNBP2 N-terminal like b.	Striatin.	0.754
LOC102194045	strn3	ENSPNYP00000019208	ENSPNYP00000018165	CTTNBP2 N-terminal like b.	Striatin, calmodulin binding protein 3.	0.754