81 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sqstm1	Sequestosome 1. (428 aa)
	aup1	AUP1 lipid droplet regulating VLDL assembly factor. (411 aa)
	faf2	Fas associated factor family member 2. (445 aa)
	ubxn2a	UBX domain protein 2A. (249 aa)
	marchf7	Membrane-associated ring finger (C3HC4) 7. (783 aa)
	vps36	Vacuolar protein sorting 36 homolog. (382 aa)
	tp53inp2	Uncharacterized protein. (181 aa)
	bub3	BUB3 mitotic checkpoint protein. (326 aa)
	tnfaip3	Tumor necrosis factor, alpha-induced protein 3. (818 aa)
	nbr1	NBR1 autophagy cargo receptor a. (1070 aa)
	LOC102215228	NBR1 autophagy cargo receptor b. (693 aa)
	tollip	Toll interacting protein. (275 aa)
	LOC102196725	Uncharacterized protein. (471 aa)
	ubap1	Ubiquitin associated protein 1. (469 aa)
	ubr5	Ubiquitin protein ligase E3 component n-recognin 5. (2433 aa)
	ENSPNYP00000005864	UEV domain-containing protein. (497 aa)
	LOC102193458	Inflammation and lipid regulator with UBA-like and NBR1-like domains. (280 aa)
	ubxn11	UBX domain protein 11. (394 aa)
	ascc2	Activating signal cointegrator 1 complex subunit 2. (773 aa)
	usp13	Ubiquitinyl hydrolase 1. (865 aa)
	LOC102200670	Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (662 aa)
	tab3	TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (612 aa)
	LOC102207417	Uncharacterized protein; Belongs to the TOM1 family. (499 aa)
	LOC102211337	Uncharacterized protein. (611 aa)
	ENSPNYP00000010639	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (94 aa)
	ENSPNYP00000011207	Ubiquitin-like domain-containing protein. (128 aa)
	wdr92	WD repeat domain 92. (354 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (773 aa)
	trim32	Tripartite motif containing 32. (693 aa)
	prkn	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (425 aa)
	nsfl1c	NSFL1 (p97) cofactor (p47). (374 aa)
	smarcad1	Uncharacterized protein. (823 aa)
	usp16	Ubiquitin carboxyl-terminal hydrolase. (800 aa)
	tab2	TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (738 aa)
	LOC102209955	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (89 aa)
	vps28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (222 aa)
	ubxn7	UBX domain protein 7. (540 aa)
	cuedc2	CUE domain containing 2. (283 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (517 aa)
	uchl3	Ubiquitin carboxyl-terminal hydrolase. (227 aa)
	LOC102196988	UBA domain-containing protein. (335 aa)
	rbck1	RanBP-type and C3HC4-type zinc finger containing 1. (516 aa)
	LOC102215638	RPN13_C domain-containing protein. (416 aa)
	LOC102193127	Uncharacterized protein. (460 aa)
	uchl1	Ubiquitin carboxyl-terminal hydrolase. (220 aa)
	sharpin	SHANK-associated RH domain interacting protein. (436 aa)
	ENSPNYP00000019510	VHS domain-containing protein. (117 aa)
	LOC102193970	Zgc:123278. (107 aa)
	tsg101	Tumor susceptibility 101a. (390 aa)
	rad23a	RAD23 homolog A, nucleotide excision repair protein a. (396 aa)
	ENSPNYP00000020357	Uncharacterized protein. (62 aa)
	LOC102212437	UEV and lactate/malate dehyrogenase domains. (432 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (521 aa)
	LOC102211984	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (757 aa)
	TOM1L2	Target of myb1 like 2 membrane trafficking protein. (199 aa)
	wdr48	WD repeat domain 48b. (677 aa)
	mdm2	MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (457 aa)
	ILRUN	Inflammation and lipid regulator with UBA-like and NBR1-like domains. (288 aa)
	otub1	Ubiquitin thioesterase. (279 aa)
	tepsin	TEPSIN adaptor related protein complex 4 accessory protein. (519 aa)
	rae1	Ribonucleic acid export 1. (369 aa)
	LOC102199849	Uncharacterized protein. (660 aa)
	cuedc1	CUE domain containing 1b. (396 aa)
	LOC102214540	Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (522 aa)
	armc9	Armadillo repeat containing 9. (659 aa)
	ubxn10	UBX domain protein 10. (215 aa)
	ENSPNYP00000028304	VHS domain-containing protein. (129 aa)
	faf1	Fas (TNFRSF6) associated factor 1. (676 aa)
	plaa	Phospholipase A2-activating protein. (797 aa)
	sprtn	SprT-like N-terminal domain. (621 aa)
	rnf31	Uncharacterized protein. (1109 aa)
	LOC102210430	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (76 aa)
	LOC102204727	Sharpin and rbck1 related. (711 aa)
	fbxo7	F-box protein 7. (469 aa)
	OTUB2	OTU domain-containing protein. (224 aa)
	usp5	Ubiquitin carboxyl-terminal hydrolase. (829 aa)
	LOC102192570	Uncharacterized protein. (352 aa)
	rnf168	Ring finger protein 168. (404 aa)
	rnf8	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (467 aa)
	LOC102204952	Nedd4 binding protein 1. (831 aa)
	adrm1	Adhesion regulating molecule 1. (410 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000005864	ENSPNYP00000011207	ENSPNYP00000005864	ENSPNYP00000011207	UEV domain-containing protein.	Ubiquitin-like domain-containing protein.	0.517
ENSPNYP00000005864	LOC102192570	ENSPNYP00000005864	ENSPNYP00000030542	UEV domain-containing protein.	Uncharacterized protein.	0.877
ENSPNYP00000005864	LOC102196725	ENSPNYP00000005864	ENSPNYP00000004778	UEV domain-containing protein.	Uncharacterized protein.	0.517
ENSPNYP00000005864	LOC102204727	ENSPNYP00000005864	ENSPNYP00000029967	UEV domain-containing protein.	Sharpin and rbck1 related.	0.983
ENSPNYP00000005864	rad23a	ENSPNYP00000005864	ENSPNYP00000020166	UEV domain-containing protein.	RAD23 homolog A, nucleotide excision repair protein a.	0.517
ENSPNYP00000005864	rbck1	ENSPNYP00000005864	ENSPNYP00000016789	UEV domain-containing protein.	RanBP-type and C3HC4-type zinc finger containing 1.	0.983
ENSPNYP00000005864	rnf31	ENSPNYP00000005864	ENSPNYP00000029465	UEV domain-containing protein.	Uncharacterized protein.	0.877
ENSPNYP00000005864	sharpin	ENSPNYP00000005864	ENSPNYP00000018979	UEV domain-containing protein.	SHANK-associated RH domain interacting protein.	0.986
ENSPNYP00000005864	tab2	ENSPNYP00000005864	ENSPNYP00000014086	UEV domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 2.	0.454
ENSPNYP00000005864	tab3	ENSPNYP00000005864	ENSPNYP00000007908	UEV domain-containing protein.	TGF-beta activated kinase 1 (MAP3K7) binding protein 3.	0.616
ENSPNYP00000005864	tnfaip3	ENSPNYP00000005864	ENSPNYP00000001774	UEV domain-containing protein.	Tumor necrosis factor, alpha-induced protein 3.	0.790
ENSPNYP00000010639	ENSPNYP00000011207	ENSPNYP00000010639	ENSPNYP00000011207	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Ubiquitin-like domain-containing protein.	0.504
ENSPNYP00000010639	LOC102196725	ENSPNYP00000010639	ENSPNYP00000004778	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	Uncharacterized protein.	0.504
ENSPNYP00000010639	rad23a	ENSPNYP00000010639	ENSPNYP00000020166	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	RAD23 homolog A, nucleotide excision repair protein a.	0.504
ENSPNYP00000011207	ENSPNYP00000005864	ENSPNYP00000011207	ENSPNYP00000005864	Ubiquitin-like domain-containing protein.	UEV domain-containing protein.	0.517
ENSPNYP00000011207	ENSPNYP00000010639	ENSPNYP00000011207	ENSPNYP00000010639	Ubiquitin-like domain-containing protein.	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.	0.504
ENSPNYP00000011207	LOC102192570	ENSPNYP00000011207	ENSPNYP00000030542	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.517
ENSPNYP00000011207	LOC102193127	ENSPNYP00000011207	ENSPNYP00000018447	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.740
ENSPNYP00000011207	LOC102193970	ENSPNYP00000011207	ENSPNYP00000019998	Ubiquitin-like domain-containing protein.	Zgc:123278.	0.583
ENSPNYP00000011207	LOC102196725	ENSPNYP00000011207	ENSPNYP00000004778	Ubiquitin-like domain-containing protein.	Uncharacterized protein.	0.818