32 items (Pundamilia nyererei) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	edem1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (636 aa)
	hspa5	Heat shock protein 5; Belongs to the heat shock protein 70 family. (633 aa)
	tram2	Translocating chain-associated membrane protein; Belongs to the TRAM family. (369 aa)
	sec61g	SEC61 translocon gamma subunit. (68 aa)
	LOC102213464	Translocating chain-associated membrane protein; Belongs to the TRAM family. (371 aa)
	ENSPNYP00000028210	Uncharacterized protein. (52 aa)
	sec61a1	Plug_translocon domain-containing protein. (476 aa)
	sec61b	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
	srp68	Signal recognition particle subunit SRP68; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP68 family. (591 aa)
	sec63	SEC63 homolog, protein translocation regulator. (710 aa)
	mfsd11	Major facilitator superfamily domain containing 11. (454 aa)
	srpra	SRP receptor subunit alpha. (647 aa)
	ssr3	Signal sequence receptor, gamma. (185 aa)
	srp9	Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (86 aa)
	spcs2	Signal peptidase complex subunit 2. (215 aa)
	srp54	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
	ENSPNYP00000012236	Uncharacterized protein. (133 aa)
	zfand2a	Zinc finger, AN1-type domain 2A. (145 aa)
	sgta	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. (330 aa)
	sgtb	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. (307 aa)
	srp14	Signal recognition particle 14. (110 aa)
	spcs3	Signal peptidase complex subunit 3. (133 aa)
	tram1	Translocating chain-associated membrane protein; Belongs to the TRAM family. (370 aa)
	srp72	Signal recognition particle subunit SRP72; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane; Belongs to the SRP72 family. (668 aa)
	ttc33	Tetratricopeptide repeat domain 33. (272 aa)
	LOC102214571	Uncharacterized protein. (446 aa)
	sec62	SEC62 homolog, preprotein translocation factor. (349 aa)
	ENSPNYP00000005359	Uncharacterized protein. (99 aa)
	get3	ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
	LOC102204132	Plug_translocon domain-containing protein. (476 aa)
	srprb	SRP receptor subunit beta. (276 aa)
	spcs1	Signal peptidase complex subunit 1. (102 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000005359	LOC102204132	ENSPNYP00000005359	ENSPNYP00000008001	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.698
ENSPNYP00000005359	edem1	ENSPNYP00000005359	ENSPNYP00000021474	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.499
ENSPNYP00000005359	sec61a1	ENSPNYP00000005359	ENSPNYP00000026797	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.698
ENSPNYP00000005359	sec61b	ENSPNYP00000005359	ENSPNYP00000023701	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.529
ENSPNYP00000005359	sec62	ENSPNYP00000005359	ENSPNYP00000011052	Uncharacterized protein.	SEC62 homolog, preprotein translocation factor.	0.494
ENSPNYP00000005359	sec63	ENSPNYP00000005359	ENSPNYP00000018039	Uncharacterized protein.	SEC63 homolog, protein translocation regulator.	0.947
ENSPNYP00000005359	sgta	ENSPNYP00000005359	ENSPNYP00000000842	Uncharacterized protein.	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.	0.497
ENSPNYP00000005359	sgtb	ENSPNYP00000005359	ENSPNYP00000000850	Uncharacterized protein.	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.	0.497
ENSPNYP00000005359	spcs2	ENSPNYP00000005359	ENSPNYP00000013506	Uncharacterized protein.	Signal peptidase complex subunit 2.	0.761
ENSPNYP00000005359	srp54	ENSPNYP00000005359	ENSPNYP00000012917	Uncharacterized protein.	Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily.	0.455
ENSPNYP00000005359	ttc33	ENSPNYP00000005359	ENSPNYP00000003920	Uncharacterized protein.	Tetratricopeptide repeat domain 33.	0.494
ENSPNYP00000012236	LOC102204132	ENSPNYP00000012236	ENSPNYP00000008001	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.698
ENSPNYP00000012236	edem1	ENSPNYP00000012236	ENSPNYP00000021474	Uncharacterized protein.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.499
ENSPNYP00000012236	sec61a1	ENSPNYP00000012236	ENSPNYP00000026797	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.698
ENSPNYP00000012236	sec61b	ENSPNYP00000012236	ENSPNYP00000023701	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.529
ENSPNYP00000012236	sec62	ENSPNYP00000012236	ENSPNYP00000011052	Uncharacterized protein.	SEC62 homolog, preprotein translocation factor.	0.494
ENSPNYP00000012236	sec63	ENSPNYP00000012236	ENSPNYP00000018039	Uncharacterized protein.	SEC63 homolog, protein translocation regulator.	0.947
ENSPNYP00000012236	sgta	ENSPNYP00000012236	ENSPNYP00000000842	Uncharacterized protein.	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha.	0.497
ENSPNYP00000012236	sgtb	ENSPNYP00000012236	ENSPNYP00000000850	Uncharacterized protein.	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta.	0.497
ENSPNYP00000012236	spcs2	ENSPNYP00000012236	ENSPNYP00000013506	Uncharacterized protein.	Signal peptidase complex subunit 2.	0.761