(26 nodes) Regulation of viral genome replication network (Pundamilia nyererei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	mphosph8	Chromo domain-containing protein. (1596 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (299 aa)
	znfx1	Zinc finger, NFX1-type containing 1. (1818 aa)
	tasor	Uncharacterized protein. (1429 aa)
	pde12	Phosphodiesterase 12. (592 aa)
	ENSPNYP00000018786	Uncharacterized protein; Belongs to the protein kinase superfamily. (484 aa)
	ENSPNYP00000018833	Uncharacterized protein. (661 aa)
	hmga2	Uncharacterized protein. (114 aa)
	morc2	MORC family CW-type zinc finger 2. (1010 aa)
	mavs	CARD_2 domain-containing protein. (555 aa)
	LOC102216068	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1511 aa)
	LOC102206926	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC102199243	BH4_2 domain-containing protein. (198 aa)
	LOC102204952	Nedd4 binding protein 1. (831 aa)
	top2b	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1603 aa)
	aicda	Activation-induced cytidine deaminase. (210 aa)
	ENSPNYP00000003876	Transcription activation suppressor b. (1653 aa)
	ifih1	Interferon induced with helicase C domain 1. (983 aa)
	fkbp6	Peptidylprolyl isomerase. (316 aa)
	adar	Adenosine deaminase RNA specific. (1359 aa)
	ENSPNYP00000006625	Poly [ADP-ribose] polymerase. (599 aa)
	ENSPNYP00000031662	Protein kinase domain-containing protein. (266 aa)
	LOC102203234	Damage-specific DNA binding protein 1. (573 aa)
	ppid	Peptidylprolyl isomerase D. (348 aa)
	LOC102208280	Damage-specific DNA binding protein 1. (562 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000003876	mphosph8	ENSPNYP00000003876	ENSPNYP00000009108	Transcription activation suppressor b.	Chromo domain-containing protein.	0.694
ENSPNYP00000018786	adar	ENSPNYP00000018786	ENSPNYP00000006302	Uncharacterized protein; Belongs to the protein kinase superfamily.	Adenosine deaminase RNA specific.	0.608
ENSPNYP00000018786	ifih1	ENSPNYP00000018786	ENSPNYP00000003897	Uncharacterized protein; Belongs to the protein kinase superfamily.	Interferon induced with helicase C domain 1.	0.826
ENSPNYP00000018786	mavs	ENSPNYP00000018786	ENSPNYP00000024020	Uncharacterized protein; Belongs to the protein kinase superfamily.	CARD_2 domain-containing protein.	0.517
ENSPNYP00000018833	adar	ENSPNYP00000018833	ENSPNYP00000006302	Uncharacterized protein.	Adenosine deaminase RNA specific.	0.608
ENSPNYP00000018833	ifih1	ENSPNYP00000018833	ENSPNYP00000003897	Uncharacterized protein.	Interferon induced with helicase C domain 1.	0.826
ENSPNYP00000018833	mavs	ENSPNYP00000018833	ENSPNYP00000024020	Uncharacterized protein.	CARD_2 domain-containing protein.	0.517
ENSPNYP00000031662	adar	ENSPNYP00000031662	ENSPNYP00000006302	Protein kinase domain-containing protein.	Adenosine deaminase RNA specific.	0.608
ENSPNYP00000031662	ifih1	ENSPNYP00000031662	ENSPNYP00000003897	Protein kinase domain-containing protein.	Interferon induced with helicase C domain 1.	0.826
ENSPNYP00000031662	mavs	ENSPNYP00000031662	ENSPNYP00000024020	Protein kinase domain-containing protein.	CARD_2 domain-containing protein.	0.517
LOC102199243	LOC102206926	ENSPNYP00000029059	ENSPNYP00000024693	BH4_2 domain-containing protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.470
LOC102199243	ppid	ENSPNYP00000029059	ENSPNYP00000028482	BH4_2 domain-containing protein.	Peptidylprolyl isomerase D.	0.744
LOC102203234	LOC102208280	ENSPNYP00000032109	ENSPNYP00000013871	Damage-specific DNA binding protein 1.	Damage-specific DNA binding protein 1.	0.946
LOC102203234	mphosph8	ENSPNYP00000032109	ENSPNYP00000009108	Damage-specific DNA binding protein 1.	Chromo domain-containing protein.	0.440
LOC102206926	LOC102199243	ENSPNYP00000024693	ENSPNYP00000029059	Tumor necrosis factor b (TNF superfamily, member 2).	BH4_2 domain-containing protein.	0.470
LOC102206926	bcl2	ENSPNYP00000024693	ENSPNYP00000016323	Tumor necrosis factor b (TNF superfamily, member 2).	BCL2 apoptosis regulator b.	0.470
LOC102206926	mphosph8	ENSPNYP00000024693	ENSPNYP00000009108	Tumor necrosis factor b (TNF superfamily, member 2).	Chromo domain-containing protein.	0.552
LOC102208280	LOC102203234	ENSPNYP00000013871	ENSPNYP00000032109	Damage-specific DNA binding protein 1.	Damage-specific DNA binding protein 1.	0.946
LOC102208280	mphosph8	ENSPNYP00000013871	ENSPNYP00000009108	Damage-specific DNA binding protein 1.	Chromo domain-containing protein.	0.440
adar	ENSPNYP00000018786	ENSPNYP00000006302	ENSPNYP00000018786	Adenosine deaminase RNA specific.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.608