STRINGSTRING
ext2 ext2 syvn1 syvn1 mmgt1 mmgt1 faf2 faf2 LOC102196877 LOC102196877 stt3a stt3a spcs3 spcs3 map3k5 map3k5 LOC102211267 LOC102211267 hyou1 hyou1 emc7 emc7 LOC102208025 LOC102208025 pigh pigh dpm2 dpm2 pigu pigu selenos selenos sel1l sel1l ENSPNYP00000005359 ENSPNYP00000005359 LOC102198640 LOC102198640 pigk pigk rpn2 rpn2 LOC102210183 LOC102210183 krtcap2 krtcap2 spcs1 spcs1 emc2 emc2 hm13 hm13 LOC102196030 LOC102196030 LOC102205272 LOC102205272 derl2 derl2 srprb srprb LOC102204132 LOC102204132 get3 get3 LOC102206697 LOC102206697 ENSPNYP00000008416 ENSPNYP00000008416 fam167a fam167a ENSPNYP00000008814 ENSPNYP00000008814 ENSPNYP00000008867 ENSPNYP00000008867 insig1 insig1 sptssb sptssb LOC102193076 LOC102193076 aup1 aup1 ufd1 ufd1 pigt pigt pigc pigc zw10 zw10 alg14 alg14 ENSPNYP00000012236 ENSPNYP00000012236 ppib ppib pigq pigq spcs2 spcs2 pdia3 pdia3 emc1 emc1 ubxn7 ubxn7 pigm pigm fam8a1 fam8a1 LOC102200540 LOC102200540 ormdl1 ormdl1 camlg camlg srpra srpra ddost ddost STT3B STT3B tap1 tap1 derl1 derl1 LOC102204013 LOC102204013 sec63 sec63 nbas nbas sptssa sptssa gpaa1 gpaa1 LOC102196306 LOC102196306 tmem258 tmem258 rint1 rint1 ganab ganab emc10 emc10 emc8 emc8 LOC102210746 LOC102210746 emc6 emc6 sec61b sec61b ern1 ern1 vcp vcp tusc3 tusc3 amfr amfr piga piga ENSPNYP00000025296 ENSPNYP00000025296 LOC102215894 LOC102215894 dad1 dad1 sec61a1 sec61a1 rpn1 rpn1 pigs pigs emc4 emc4 ENSPNYP00000028210 ENSPNYP00000028210 faf1 faf1 emc9 emc9 ost4 ost4 pdia4 pdia4 insig2 insig2 sptlc1 sptlc1 ENSPNYP00000031531 ENSPNYP00000031531 ostc ostc LOC102197578 LOC102197578 hspa5 hspa5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ext2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
syvn1Synovial apoptosis inhibitor 1, synoviolin. (562 aa)
mmgt1Membrane magnesium transporter 1. (130 aa)
faf2Fas associated factor family member 2. (445 aa)
LOC102196877Transporter associated with antigen processing, subunit type t, teleost specific. (751 aa)
stt3aSTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
spcs3Signal peptidase complex subunit 3. (133 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1373 aa)
LOC102211267ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
hyou1Hypoxia up-regulated 1. (978 aa)
emc7ER membrane protein complex subunit 7. (240 aa)
LOC102208025ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
pighPhosphatidylinositol glycan anchor biosynthesis, class H. (181 aa)
dpm2Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (83 aa)
piguPhosphatidylinositol glycan anchor biosynthesis, class U. (435 aa)
selenosSelenoprotein S. (189 aa)
sel1lSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (805 aa)
ENSPNYP00000005359Uncharacterized protein. (99 aa)
LOC102198640Zgc:136908; Belongs to the AAA ATPase family. (806 aa)
pigkGPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (356 aa)
rpn2Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (663 aa)
LOC102210183ER membrane protein complex subunit 3; Belongs to the EMC3 family. (260 aa)
krtcap2Keratinocyte associated protein 2. (136 aa)
spcs1Signal peptidase complex subunit 1. (102 aa)
emc2ER membrane protein complex subunit 2. (297 aa)
hm13Histocompatibility (minor) 13. (392 aa)
LOC102196030Magnesium transporter 1. (398 aa)
LOC102205272STT3 oligosaccharyltransferase complex catalytic subunit B. (811 aa)
derl2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
srprbSRP receptor subunit beta. (276 aa)
LOC102204132Plug_translocon domain-containing protein. (476 aa)
get3ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] (341 aa)
LOC102206697ER membrane protein complex subunit 3; Belongs to the EMC3 family. (261 aa)
ENSPNYP00000008416Uncharacterized protein. (223 aa)
fam167aFamily with sequence similarity 167 member Ab. (202 aa)
ENSPNYP00000008814Protein kinase domain-containing protein. (268 aa)
ENSPNYP00000008867Protein kinase domain-containing protein. (193 aa)
insig1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. (276 aa)
sptssbSerine palmitoyltransferase, small subunit B. (80 aa)
LOC102193076Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
aup1AUP1 lipid droplet regulating VLDL assembly factor. (411 aa)
ufd1Ubiquitin recognition factor in ER associated degradation 1. (310 aa)
pigtPhosphatidylinositol glycan anchor biosynthesis, class T. (643 aa)
pigcPhosphatidylinositol glycan anchor biosynthesis, class C. (294 aa)
zw10Zw10 kinetochore protein. (766 aa)
alg14ALG14 UDP-N-acetylglucosaminyltransferase subunit. (213 aa)
ENSPNYP00000012236Uncharacterized protein. (133 aa)
ppibPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
pigqPhosphatidylinositol glycan anchor biosynthesis, class Q. (575 aa)
spcs2Signal peptidase complex subunit 2. (215 aa)
pdia3Protein disulfide-isomerase. (492 aa)
emc1ER membrane protein complex subunit 1. (965 aa)
ubxn7UBX domain protein 7. (540 aa)
pigmGPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. (409 aa)
fam8a1Family with sequence similarity 8 member A1a. (303 aa)
LOC102200540Transporter associated with antigen processing, subunit type a. (720 aa)
ormdl1ORM1-like protein; Negative regulator of sphingolipid synthesis. (153 aa)
camlgCalcium modulating ligand. (283 aa)
srpraSRP receptor subunit alpha. (647 aa)
ddostDolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] (466 aa)
STT3BSTT3 oligosaccharyltransferase complex catalytic subunit B. (804 aa)
tap1Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (738 aa)
derl1Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (252 aa)
LOC102204013Si:ch211-1i11.3. (1326 aa)
sec63SEC63 homolog, protein translocation regulator. (710 aa)
nbasNeuroblastoma amplified sequence. (2166 aa)
sptssaSerine palmitoyltransferase, small subunit A. (68 aa)
gpaa1Glycosylphosphatidylinositol anchor attachment 1. (615 aa)
LOC102196306Endoplasmic reticulum to nucleus signaling 2. (979 aa)
tmem258Transmembrane protein 258. (79 aa)
rint1RAD50 interactor 1. (784 aa)
ganabGlucosidase, alpha; neutral AB; Belongs to the glycosyl hydrolase 31 family. (907 aa)
emc10ER membrane protein complex subunit 10. (255 aa)
emc8ER membrane protein complex subunit 8. (204 aa)
LOC102210746Family with sequence similarity 8 member A1b. (331 aa)
emc6ER membrane protein complex subunit 6. (110 aa)
sec61bProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (97 aa)
ern1Endoplasmic reticulum to nucleus signaling 1. (1088 aa)
vcpValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
tusc3Tumor suppressor candidate 3. (332 aa)
amfrAutocrine motility factor receptor b. (623 aa)
pigaPhosphatidylinositol glycan anchor biosynthesis, class A. (477 aa)
ENSPNYP00000025296Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (118 aa)
LOC102215894TAP binding protein (tapasin), tandem duplicate 2. (433 aa)
dad1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (113 aa)
sec61a1Plug_translocon domain-containing protein. (476 aa)
rpn1Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (600 aa)
pigsPhosphatidylinositol glycan anchor biosynthesis, class S. (562 aa)
emc4ER membrane protein complex subunit 4; Belongs to the EMC4 family. (189 aa)
ENSPNYP00000028210Uncharacterized protein. (52 aa)
faf1Fas (TNFRSF6) associated factor 1. (676 aa)
emc9ER membrane protein complex subunit 9. (205 aa)
ost4Oligosaccharyltransferase complex subunit 4 (non-catalytic). (37 aa)
pdia4Protein disulfide-isomerase A4; Belongs to the protein disulfide isomerase family. (639 aa)
insig2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (241 aa)
sptlc1Serine palmitoyltransferase, long chain base subunit 1. (509 aa)
ENSPNYP00000031531Protein kinase domain-containing protein. (274 aa)
ostcOligosaccharyltransferase complex subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All s [...] (149 aa)
LOC102197578Ring finger protein 139. (550 aa)
hspa5Heat shock protein 5; Belongs to the heat shock protein 70 family. (633 aa)
Your Current Organism:
Pundamilia nyererei
NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei
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