(6 nodes) Mre11 complex network (Pundamilia nyererei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102215705	Checkpoint kinase 2. (476 aa)
	rad50	RAD50 homolog, double strand break repair protein. (1312 aa)
	mre11	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (689 aa)
	ENSPNYP00000006833	Uncharacterized protein. (255 aa)
	ENSPNYP00000027632	SAE2 domain-containing protein. (75 aa)
	atm	Non-specific serine/threonine protein kinase. (3051 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNYP00000006833	ENSPNYP00000027632	ENSPNYP00000006833	ENSPNYP00000027632	Uncharacterized protein.	SAE2 domain-containing protein.	0.974
ENSPNYP00000006833	LOC102215705	ENSPNYP00000006833	ENSPNYP00000018807	Uncharacterized protein.	Checkpoint kinase 2.	0.770
ENSPNYP00000006833	atm	ENSPNYP00000006833	ENSPNYP00000014790	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.984
ENSPNYP00000006833	mre11	ENSPNYP00000006833	ENSPNYP00000024222	Uncharacterized protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
ENSPNYP00000027632	ENSPNYP00000006833	ENSPNYP00000027632	ENSPNYP00000006833	SAE2 domain-containing protein.	Uncharacterized protein.	0.974
ENSPNYP00000027632	LOC102215705	ENSPNYP00000027632	ENSPNYP00000018807	SAE2 domain-containing protein.	Checkpoint kinase 2.	0.483
ENSPNYP00000027632	atm	ENSPNYP00000027632	ENSPNYP00000014790	SAE2 domain-containing protein.	Non-specific serine/threonine protein kinase.	0.936
ENSPNYP00000027632	mre11	ENSPNYP00000027632	ENSPNYP00000024222	SAE2 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.990
ENSPNYP00000027632	rad50	ENSPNYP00000027632	ENSPNYP00000020424	SAE2 domain-containing protein.	RAD50 homolog, double strand break repair protein.	0.975
LOC102215705	ENSPNYP00000006833	ENSPNYP00000018807	ENSPNYP00000006833	Checkpoint kinase 2.	Uncharacterized protein.	0.770
LOC102215705	ENSPNYP00000027632	ENSPNYP00000018807	ENSPNYP00000027632	Checkpoint kinase 2.	SAE2 domain-containing protein.	0.483
LOC102215705	atm	ENSPNYP00000018807	ENSPNYP00000014790	Checkpoint kinase 2.	Non-specific serine/threonine protein kinase.	0.990
LOC102215705	mre11	ENSPNYP00000018807	ENSPNYP00000024222	Checkpoint kinase 2.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.848
LOC102215705	rad50	ENSPNYP00000018807	ENSPNYP00000020424	Checkpoint kinase 2.	RAD50 homolog, double strand break repair protein.	0.770
atm	ENSPNYP00000006833	ENSPNYP00000014790	ENSPNYP00000006833	Non-specific serine/threonine protein kinase.	Uncharacterized protein.	0.984
atm	ENSPNYP00000027632	ENSPNYP00000014790	ENSPNYP00000027632	Non-specific serine/threonine protein kinase.	SAE2 domain-containing protein.	0.936
atm	LOC102215705	ENSPNYP00000014790	ENSPNYP00000018807	Non-specific serine/threonine protein kinase.	Checkpoint kinase 2.	0.990
atm	mre11	ENSPNYP00000014790	ENSPNYP00000024222	Non-specific serine/threonine protein kinase.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.995
atm	rad50	ENSPNYP00000014790	ENSPNYP00000020424	Non-specific serine/threonine protein kinase.	RAD50 homolog, double strand break repair protein.	0.984
mre11	ENSPNYP00000006833	ENSPNYP00000024222	ENSPNYP00000006833	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Uncharacterized protein.	0.998