(54 nodes) ATPase, AAA-type, core network (Pundamilia nyererei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	atad2b	ATPase family AAA domain containing 2B. (1452 aa)
	LOC102210483	N-ethylmaleimide-sensitive factor b. (746 aa)
	SPATA5	Spermatogenesis associated 5. (828 aa)
	LOC102192144	YME1-like 1b. (717 aa)
	atad5	AAA domain-containing protein. (746 aa)
	fign	Fidgetin; Belongs to the AAA ATPase family. (742 aa)
	yme1l1	YME1-like 1a. (725 aa)
	lonp2	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (842 aa)
	LOC102192388	AAA domain-containing protein; Belongs to the AAA ATPase family. (314 aa)
	LOC102192704	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family. (381 aa)
	lonp1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. (1002 aa)
	afg3l2	AFG3-like AAA ATPase 2. (800 aa)
	LOC102198640	Zgc:136908; Belongs to the AAA ATPase family. (806 aa)
	fignl1	Fidgetin-like 1; Belongs to the AAA ATPase family. (637 aa)
	rfc2	Replication factor C (activator 1) 2. (356 aa)
	spg7	SPG7 matrix AAA peptidase subunit, paraplegin. (808 aa)
	orc1	Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (783 aa)
	LOC102212188	Zgc:153738. (738 aa)
	pex6	Peroxisomal biogenesis factor 6. (1049 aa)
	nvl	Nuclear VCP like. (858 aa)
	rfc5	Replication factor C (activator 1) 5. (342 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (436 aa)
	spata5l1	Spermatogenesis associated 5-like 1. (734 aa)
	ATAD3A	ATPase family AAA domain containing 3A. (665 aa)
	pex1	Peroxisomal biogenesis factor 1. (1247 aa)
	LOC102215641	Uncharacterized protein; Belongs to the AAA ATPase family. (435 aa)
	ENSPNYP00000013039	Katanin p60 subunit A-like 2. (341 aa)
	katna1	Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (488 aa)
	psmc5	Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (407 aa)
	rfc4	Replication factor C (activator 1) 4. (357 aa)
	LOC102206386	BC1 (ubiquinol-cytochrome c reductase) synthesis-like; Belongs to the AAA ATPase family. (420 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (396 aa)
	KATNAL1	Katanin catalytic subunit A1 like 1; Belongs to the AAA ATPase family. (317 aa)
	CLPB	ClpB homolog, mitochondrial AAA ATPase chaperonin. (312 aa)
	atad2	ATPase family AAA domain containing 2. (1466 aa)
	wrnip1	WRN helicase interacting protein 1. (614 aa)
	chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (911 aa)
	psmc6	Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (389 aa)
	trip13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (429 aa)
	LOC102214314	AAA domain-containing protein; Belongs to the AAA ATPase family. (686 aa)
	psmc3	Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (427 aa)
	atad1	ATPase family AAA domain containing 1b; Belongs to the AAA ATPase family. (364 aa)
	vcp	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	psmc2	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
	ENSPNYP00000024602	AAA domain-containing protein. (756 aa)
	LOC102194505	N-ethylmaleimide-sensitive factor a; Belongs to the AAA ATPase family. (689 aa)
	clpx	Caseinolytic mitochondrial matrix peptidase chaperone subunit b. (624 aa)
	LOC102199323	Si:ch1073-174d20.2; Belongs to the AAA ATPase family. (666 aa)
	FIGNL2	Fidgetin like 2. (690 aa)
	psmc1	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (440 aa)
	psmc4	Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
	ENSPNYP00000030068	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family. (357 aa)
	rfc1	Replication factor C subunit 1. (1153 aa)
	nav3	Neuron navigator 3. (2272 aa)

Your Current Organism:

Pundamilia nyererei

NCBI taxonomy Id: 303518
Other names: Haplochromis nyererei, P. nyererei

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLPB	ENSPNYP00000013039	ENSPNYP00000017468	ENSPNYP00000013039	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Katanin p60 subunit A-like 2.	0.565
CLPB	LOC102192144	ENSPNYP00000017468	ENSPNYP00000002377	ClpB homolog, mitochondrial AAA ATPase chaperonin.	YME1-like 1b.	0.499
CLPB	LOC102199323	ENSPNYP00000017468	ENSPNYP00000026620	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Si:ch1073-174d20.2; Belongs to the AAA ATPase family.	0.465
CLPB	LOC102206386	ENSPNYP00000017468	ENSPNYP00000016356	ClpB homolog, mitochondrial AAA ATPase chaperonin.	BC1 (ubiquinol-cytochrome c reductase) synthesis-like; Belongs to the AAA ATPase family.	0.465
CLPB	LOC102214314	ENSPNYP00000017468	ENSPNYP00000021566	ClpB homolog, mitochondrial AAA ATPase chaperonin.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.465
CLPB	afg3l2	ENSPNYP00000017468	ENSPNYP00000005468	ClpB homolog, mitochondrial AAA ATPase chaperonin.	AFG3-like AAA ATPase 2.	0.465
CLPB	clpx	ENSPNYP00000017468	ENSPNYP00000026464	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Caseinolytic mitochondrial matrix peptidase chaperone subunit b.	0.743
CLPB	lonp1	ENSPNYP00000017468	ENSPNYP00000005356	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.	0.917
CLPB	lonp2	ENSPNYP00000017468	ENSPNYP00000004768	ClpB homolog, mitochondrial AAA ATPase chaperonin.	Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-.	0.917
CLPB	spg7	ENSPNYP00000017468	ENSPNYP00000006385	ClpB homolog, mitochondrial AAA ATPase chaperonin.	SPG7 matrix AAA peptidase subunit, paraplegin.	0.465
CLPB	yme1l1	ENSPNYP00000017468	ENSPNYP00000004358	ClpB homolog, mitochondrial AAA ATPase chaperonin.	YME1-like 1a.	0.499
ENSPNYP00000013039	CLPB	ENSPNYP00000013039	ENSPNYP00000017468	Katanin p60 subunit A-like 2.	ClpB homolog, mitochondrial AAA ATPase chaperonin.	0.565
ENSPNYP00000013039	ENSPNYP00000024602	ENSPNYP00000013039	ENSPNYP00000024602	Katanin p60 subunit A-like 2.	AAA domain-containing protein.	0.481
ENSPNYP00000013039	ENSPNYP00000030068	ENSPNYP00000013039	ENSPNYP00000030068	Katanin p60 subunit A-like 2.	ATPase_AAA_core domain-containing protein; Belongs to the AAA ATPase family.	0.607
ENSPNYP00000013039	FIGNL2	ENSPNYP00000013039	ENSPNYP00000028896	Katanin p60 subunit A-like 2.	Fidgetin like 2.	0.481
ENSPNYP00000013039	KATNAL1	ENSPNYP00000013039	ENSPNYP00000017088	Katanin p60 subunit A-like 2.	Katanin catalytic subunit A1 like 1; Belongs to the AAA ATPase family.	0.537
ENSPNYP00000013039	LOC102192388	ENSPNYP00000013039	ENSPNYP00000004954	Katanin p60 subunit A-like 2.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.570
ENSPNYP00000013039	LOC102192704	ENSPNYP00000013039	ENSPNYP00000005060	Katanin p60 subunit A-like 2.	ATPase family AAA domain containing 1a; Belongs to the AAA ATPase family.	0.567
ENSPNYP00000013039	LOC102194505	ENSPNYP00000013039	ENSPNYP00000025602	Katanin p60 subunit A-like 2.	N-ethylmaleimide-sensitive factor a; Belongs to the AAA ATPase family.	0.480
ENSPNYP00000013039	LOC102198640	ENSPNYP00000013039	ENSPNYP00000005469	Katanin p60 subunit A-like 2.	Zgc:136908; Belongs to the AAA ATPase family.	0.584